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Biomedical subjects

E Popkhristova

Publications and source records attributed to E Popkhristova.

At least 19 recordsLinked to original sources

[The pathomorphology of complicated colorectal cancer and the stages in the development of the tumor process].

A comprehensive pathomorphological assessment is done in 385 patients presenting complicated colorectal carcinoma, covering the period 1990 through 1995. The patients are distributed in 4 groups according to stage, with those in stage III being the most numerous--141 cases. The growth pattern of the neoplasm is as follows: exophytic growth--110 cases, ulcerous growth--57, cup-like growth--13, and endophytic growth--205 cases. On establishing metastatic lymph nodes within I and II lymph collectors, prophylactic postoperative chemo- and immunotherapy are undertaken. In case of lymph nodes present in III lymph collector, the operation is taken to be relatively radical, and for that reason chemo- and immunotherapy assume a therapeutic character.

Adenocarcinoma↗

[Dermatofibrosarcoma protuberans--a clinico-anatomical and immunohistochemical study].

This is a report on the clinical, anatomical and immunohistochemical study of thirty patients presenting dermatofibrosarcoma protuberans. Its incidence (4.8 percent), covering a 15-year period in a specialized oncological unit, wider age range and high rate of relapses (66.6 percent) are established as the result of clinical and anatomical revision. The latter findings necessitate radical removal of the neoplasm as early at its primary resection. The practical implications of the so-called "spoke-like" structures, pathognomonic for histological identification of the tumor, are discussed. The immunohistochemical study for S100 [correction of C100] protein and lysozyme is negative, while alpha 1-antitrypsin reaction is positive in single rounded histiocyte-like cells which is by no means a conclusive evidence of the phenotype characteristics of the cell population in dermatofibrosarcoma protuberans.

Adolescent↗

[Plasmacytomas of the upper respiratory tract].

Nine cases of plasmocytoma of the upper airways in the current biopsy material are studied over a three-year period (1991-1993). Initially, all nine cases are clinically diagnosed as neoplasms: hemangiofibroma--one, chondrosarcoma--one, suspected carcinoma--five, and unspecified diagnosis--two. "Plasmocytoma" diagnosis is made on the ground of histological investigation of the material, supported histochemically and electron-microscopically. Some diagnostic problems (differential diagnosis inclusive) are discussed, as well as issues relating to the clinical and morphological evolution of the disease, and predilected gender and age groups.

Adult↗

[Aggressive muscular-aponeurotic fibromatosis. Its clinical picture and morphological study].

The authors report 24 cases with aggressive muscle-aponeurotic fibromatosis for the period 1985-1990. Eleven cases with proved fibrosarcoma have been studied as well. From the total 35 cases the authors have observed 5 cases with localization on the front abdominal wall in women, and the remaining cases are as follows: 9 patients with thoracic girdle (c. membri superioris); 9 patients--in the head area; 5--in the chest area; 12--in the limbs; 2--in the lumbar area.

Adolescent↗

[The modern differential diagnostic possibilities in chordoma].

The authors report five cases with chordoma. The diagnosis has been determined histologically on the basis of the operative material. The chordomas have a slow growth and a tendency to infiltrate the adjacent tissues and organs. That makes their surgical treatment difficult. A characterizing feature for them is the tendency to make recidivations and the difficulty in setting the differential diagnosis in metastasis of light-cell carcinomas.

Aged↗

[A case of carcinoid tumor of the breast].

A rare tumor of the mammary gland, built up of argyrophilic cells, with numerous metastases in the axillary lymph nodes is reported. Histochemical and electron-microscopic studied unequivocally demonstrated that this tumor belonged to the APUD system. The possible histogenesis of carcinoid tumor of the mammary gland is briefly discussed.

Apudoma↗

[A case of epidermoid cysts in the spleen].

A rare case of epidermoid cysts of the spleen in a 16-year-old boy, presenting with early clinical symptoms, is reported. In view of the extreme rarity of primary cysts of the spleen, the authors contemplate on the possibilities for establishing the diagnosis.

Adolescent↗