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Biomedical subjects

E Powell

Publications and source records attributed to E Powell.

47 records · Page 3Linked to original sources
PubMed1975

The incidence of Australia antigen in hospital staff members.

A survey of Sydney Hospital staff members for Au antigenaemia was performed during a six-month period in 1972. Nine hundred and forty-six staff members were tested by the immunoelectroosmophoresis (IEOP) method and two asymptomatic chronic carriers were detected. Subsequently, it has been hospital policy to test all new staff members. Eight hundred and ninety additional sera from staff members were obtained and 12 were found to be Au positive. Of these, only one had evidence of liver disease. The results show a slight increase in the incidence of Au positivity in hospital staff members as compared with that of the general Australian population. However, in our series the majority of chronic carriers were immigrants from countries with known high incidence of Au antigen positivity. We therefore postulate that this increase is due not to the hospital environment, but to the carrier's country of origin.

Australia↗
PubMed1974

Periurethral enterobacterial carriage in pathogenesis of recurrent urinary infection.

Periurethral carriage rates of enterobacteria have been studied in 20 normal women, 34 patients between episodes of bacteriuria, 34 patients with the "urethral syndrome," and 15 asymptomatic abacteriuric patients with a previous history of frequency and dysuria.Over a six-week period no difference in the Escherichia coli carriage rate was shown between these four groups. The carriage of all enterobacteria was slightly but significantly (P <0.05) lower in normal women compared with the patient groups but no difference was observed between the latter. There was no difference in the recovery rate and carriage of individual E. coli serotypes between the four groups.It is concluded that the presence of enterobacteria or E. coli on the periurethral area is not the principal determinant factor in the pathogenesis of recurrent urinary tract infection or the urethral syndrome and that definition of carriage status is of little practical value in management.

Adult↗
PubMedDate not supplied

Radioimmunoscintigraphy of squamous carcinomas of the head and neck.

A pilot study was carried out to assess the value of a radiolabeled antibody against epidermal growth factor receptor (EGFR1) in localizing tumors in patients with squamous carcinomas of the head and neck. Positive images of large tumours (greater than 3 cm diameter) were obtained in 8 of 11 patients after intravenous administration of 111indium-labeled EGFR1. Two patients gave equivocal results, while negative scans were obtained from the patient with the smallest tumor (1 cm diameter). There were no false-positive images. The success of this study in localizing relatively large squamous carcinomas indicates that the antibody should be evaluated in patients with smaller tumors to establish the limits of detection of the technique.

Adult↗
PubMedDate not supplied

Pediatric spine tumors with spinal cord compromise.

Twenty-nine pediatric spine tumor patients with neurologic deficit were reviewed retrospectively to evaluate tumor control, neurologic course, spinal deformity, and response to treatment. Diagnoses included 10 neuroblastomas, nine sarcomas, eight astrocytomas, and two lymphomas. Mean duration of symptoms at presentation was 8 weeks. Mean clinical follow-up was 7 years 4 months, with patient survival of 66% and a local recurrence rate of 34%. Twenty-four percent (seven of 29) of patients recovered minimal neurologic function with treatment, 76% (22 of 29) showed significant recovery, and two thirds (20 of 29) developed spinal deformity. The initial clinical response to chemotherapy appeared to be most pronounced in sarcoma patients (66% positive response).

Adolescent↗