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E Pretorius

Publications and source records attributed to E Pretorius.

25 records · Page 2Linked to original sources

Lymphocyte transformation rates of homosexual men in presence of seminal plasma.

The peripheral lymphocytes of eleven healthy homosexual men and six heterosexual males were used in microlymphocyte culture systems to compare their transformation rates in the presence of PHA-M. Two homosexual men were randomly selected from the group to investigate the influence of seminal plasma fractions on their lymphocytes. The seminal plasma fractions were obtained from heterosexual normozoospermic men. Seventy two percent of the homosexual T-cell responsiveness to PHA was inhibited compared with the lymphocytes of the heterosexual men. The lymphocytes of the homosexual male seem to be less sensitive for the inhibition components present in seminal plasma.

Adult

Sperm selection capacity of cervical mucus.

Seventeen couples who attended the Infertility Clinic for routine fertility investigations were used in the study. Complete morphological examinations were performed on the ejaculates and cervical mucus samples following coitus in order to determine the morphological selective capacity of the mucus. It was concluded that both the motility of the spermatozoa and ability of the cervical mucus to select morphological abnormal spermatozoa contributed to the high percentage of normal spermatozoa present in the cervical mucus during the post coital test.

Cervix Mucus

The immunobead technique: an indicator of disturbed sperm cervical mucus interaction.

A group of 20 couples with repeatedly poor post coital tests (PCT's) where no coital disorders or cervical mucus abnormalities were present, were included in the study. The results of the Direct Immunobead (IB) and Tray-agglutination tests were compared with the results of the sperm-cervical-mucus-contact (SCMC) and post coital tests (PCT's) of each couple in order to determine the sensitivity, specificity and predictive value of the Direct IBT as a screening test for sperm antibodies. The positive predictive value of the IBT was 80%. It was also clear that a strong positive SCMC-T result correlated with agglutinating antibodies in the semen or seminal plasma. In conclusion, the IBT is a sensitive, specific and predictable test for sperm antibodies.

Cervix Mucus

The predictive value of the postcoital test for auto- and isoimmunity to spermatozoa.

Twenty eight infertile couples with sperm antibodies were used in the study. The immunologic factors in the husbands and wives were compared with the results of the post coital test. The results of the study showed that the post coital test had a predictive value of 75% for male auto-immunity to sperm while only 37% of the females with sperm antibodies had a poor post coital test. It was concluded that the post-coital test is an important screening predictor of auto-immunity to spermatozoa.

Antibodies