[Torsion of the large intestine].
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Biomedical subjects
Publications and source records attributed to E Przybylska.
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By sulfuration of 4-methyl-1H-tetrahydro-1,5-benzodiazepinone-2 (1) its 2-thione 2 was synthesized. From this compound 2-hydrazone 3 and s-triazole derivatives 4 and 5 were obtained. Screening revealed that only compound 2 showed strong inhibitory activity in the spontaneous motility test, weak synergism with hexobarbital, weak antinflammatory activity in the carrageenin test and strong analgesic activity in the hot plate test.
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