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Biomedical subjects

E R Friedrich

Publications and source records attributed to E R Friedrich.

5 recordsLinked to original sources

[Ambulatory laparoscopy].

Based on experience with 3100 tubal sterilizations and other pelviscopic operations the following conclusions are drawn: 1. Most endoscopic gynecologic operations can be performed as outpatient procedures by experienced gynecological surgeons without increased risk for patients. But not in all cases these operations can be done on an outpatient level a priori as by many american health insurance companies expected. 2. Most short operations don't need to be performed in general anaesthesia. Risks and costs can be reduced using local analgesia or "volonelgesie". 3. Such short operations can mostly be done with a single puncture laparoscope, more punctures for additional instruments should only be made if it is necessary. 4. Patients with chronic pelvic pain are able to give support in searching and finding painful organs under "volonelgesia". The treatment of these organs can be performed by injection of a local anaesthetic or in general anaesthesia. That necessitates cooperation between gynecologists, anaesthesiologists, nurses and patients which should be part of educational and training programs.

Ambulatory Surgical Procedures↗

Postoperative hysterosalpingogram: radiographic-surgical correlation.

The hysterosalpingograms of 46 patients who underwent previous uterine or tubal surgery were reviewed. Surgical procedures performed included cesarean section, myomectomy, uterine septal repair, tubal reimplantation and reanastomosis, and fimbrioplasty/cuff salpingostomy. The procedures and their resulting hysterosalpingographic appearances are discussed.

Cesarean Section↗

Estrogen-progestin pharmacodynamics of the postmenopausal endometrium studied by thymidine labeling.

Five postmenopausal women were treated with conjugated equine estrogens, 1.25 mg tablets for 25 days, and medroxyprogesterone acetate, 10 mg tablets, in combination with the last 10 estrogen doses. Twenty-five endometrial biopsy specimens were incubated in vitro with tritiated thymidine and radioautographic slides were prepared. Within five days of estrogen treatment the thymidine labeling index (TLI) in both glands and stromal cells increased from a very low resting state to relatively high levels of DNA synthesis and cell proliferation. Within five days after addition of progestin, epithelial TLIs decreased to low levels and returned to minimal baseline levels four days after the last steroid dose. Analysis of variances indicated significant changes in epithelial cells (P less than 0.0001) confirming that the proliferative effect of estrogens was suppressed during the progestin phase. Stromal TLI changes were not significant (P = 0.46).

Autoradiography↗