Paroxysmal word deafness secondary to focal epilepsy.
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Biomedical subjects
Publications and source records attributed to E R Somerville.
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A 29-year-old man experienced intractable partial seizures as the initial manifestation of neurosyphilis. The diagnosis was made after the onset of dementia 9 months later. Both the epilepsy and dementia resolved with penicillin therapy. Syphilis should be considered in patients with adult-onset focal epilepsy, particularly if there is associated dementia. Treatment may be successful even when the diagnosis is delayed.
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The electrographic features of sleep have been studied intensively using both routine electroencephalography and polysomnography. The two sections of this paper describe and illustrate the major characteristics of sleep physiology and associated clinical electroencephalography. In the first section, criteria for definition of sleep stages are presented and correlated with the phasic and tonic physiological events noted to occur as a function of sleep stage. The phylogeny and ontogeny of sleep are discussed as well as the neurophysiological mechanisms that may underlie sleep control. The second section presents a clinically oriented description of the patterns and events of the sleep electroencephalogram as seen in a normal adult and pediatric population.
A 17-year-old epileptic was admitted to the hospital in a confused state. Electroencephalography (EEG) with polygraphic recording revealed tonic status epilepticus. Therapy with phenytoin, phenobarbital, valproic acid, and methylphenidate was unsuccessful. Intravenous diazepam exacerbated the seizures. EEG with polygraphic recording may detect clinically inapparent tonic seizures in epileptics with unexplained confusion, and when generalized paroxysmal fast activity occurs during EEG recording.
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Orthostatic transient ischemic attacks (TIA) are very much rarer than orthostatic generalized cerebral ischemia (syncope). A case is described and previous reports reviewed. Orthostatic TIA appears to occur only with large vessel occlusion. In these patients, collateral blood supply is marginal and unable to support normal postural autoregulation.