The transplantation of bone marrow cells with a change of hemoglobin pattern induced by bleeding.
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Biomedical subjects
E Radikovská
Publications and source records attributed to E Radikovská.
Bone marrow cell separation on Ficoll gradient.
Cell fraction from rat and murine bone marrow were obtained by sedimentation at unit gravity. A linear gradient of polymerized sucrose (Ficoll) was used and some properties of individual cell fractions were studied. The 3rd cell fraction containing the lymphoblasts and lymphocytes contained also stem cells.
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Haemoglobin types in peripheral blood and bone marrow cells in rats after a single blood loss.
The authors studied quantitative changes in the synthesis of haemoglobin types in rat peripheral erythrocytes and in the cells of the bone marrow erythrocytic series after a single blood loss. They demonstrated that raised synthesis of given haemoglobin types could be found in the peripheral cells 5-7 days after blood loss. These changes could already be detected in the bone marrow cells 24 hours after blood loss. The question of the probable site and level of the origin of altered haemoglobin synthesis is discussed.
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