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Biomedical subjects

E Reinold

Publications and source records attributed to E Reinold.

At least 19 recordsLinked to original sources
PubMed1992

[Umbilical blood flow relations in different segments of the umbilical cord. Part 1. Physiologic index constellation].

Based on a collective of 500 women with normal singleton pregnancies we examined the indices of flow resistance along the umbilical cord. Measurements were taken at the foetal abdominal side of the Aa. umbilicales on the one hand and at the placental insertion of the vessels on the other. According to our results we were able to establish a physiological constellation of the indices for each week of gestation, and - subsequently - for the whole duration of pregnancy. These constellations could be considered physiological. They may serve as a basis for the definition of pathological conditions.

Blood Flow Velocity↗
PubMed1992

[Diagnosis of cephalothoracopagus--a case report].

Cephalothoracopagus twins were diagnosed at 22 weeks' gestation, hence this case was diagnosed early enough antenatally to allow vaginal pregnancy termination. This case underlines the need for exact ultrasound screening during early pregnancy.

Adult↗
PubMed1992

[Umbilical blood flow relations in patients with gestosis-- gestosis-specific Doppler phenomenon].

A collective of 48 pregnant women, whose pregnancies showed signs of a pregnancy-induced hypertension or gestotic tendencies was examined by Doppler ultrasound. The subject of interest was the resistance along the umbilical cord. Measurements were taken both ends of the umbilical cords. Usually, a decline of the indices is seen, which makes the difference between the two ends (Delta F) turn out positive. Pregnancies with any sign of a gestotic development, showed elevated resistances at the placental end of the cord. The indices of the foetal abdominal insertion were just about the same. Delta F changed significantly in our group of patients. Here, the values of both sides either did not differ from one another or the placental indices even exceeded the foetal ones. We called this special constellation of umbilical indices a Doppler phenomenon characterising gestotic pregnancies.

Blood Flow Velocity↗
PubMed1992

[Human papillomavirus (HPV) DNA infections of the uterine cervix].

411 women who had dysplasia, selected from an ambulatory group as well as 240 women from a random control group were examined, by using cervical smears, which were initially diagnosed as human papilloma viruses-DNA (HPV-DNA) of the type 6/11, or 16/18, or 31/33/35. This was achieved by the in-situ nucleic acid hybridisation technique. The results of the HPV-DNA typing were tabulated with the cytological diagnosis (Munich Papanicolaou (Pap.) group-classification). The control group corresponding to Pap.Gr. I, and was HPV-DNA positive in 6 (2.5%) of the 240 cases. The group of 180 patients with a Pap.Gr. II showed a HPV-DNA positive result for 75 cases (41.7%); 57 of 99 cases (57.6%) occurred in Pap.Gr. IIID; 42 of 54 cases 77.8% (L) were found in Pap.Gr. IV (a/b), and 72 of 78 cases (92.3%) appeared in Pap.Gr. V. The HPV-DNA mixed infections became evident as the cellular dysplasia increased. The results of the HPV-DNA positive diagnosis clearly indicate a close correlation with the Pap.Gr.-classification. The HPV-DNA type 16/18 was most frequent in cervical carcinomas (Pap.Gr. V). The cyto-histological control of the 57 HPV-DNA positive cases of the untreated Pap.Gr. IIID showed a regression in 31.6% of the 18 cases after a period of 3 to 6 months (post HPV-DNA typing). These were histologically normal. In 33 cases (57.9%), there was a persisting Pap.Gr. IIID (CIN I/II) and in 6 cases (10.5%) a progredient correlation in Pap.Gr. IV a/b. The Pap. group IV (a/b) was histologically a CIN grade III.

Adolescent↗
PubMed1992

[Vaginal ultrasound studies of cervix closure with special reference to parity].

In this study, the cervical length, thickness, the width of the internal os, the cervical canal and the external os of 62 primipara and 77 multipara were measured vaginosonographically. Only patients with normal pelvic scores were examined. The measurements were carried out approx. every fortnight between the 16th and 34th gestational week. In the primipara group, the average cervical length was 36.8 mm +/- 12.0 mm, the thickness 27.8 mm +/- 4.4, the width of the internal os 6.3 +/- 2.1 mm, the cervical canal 4.2 +/- 2.0 mm and the external os 5.4 +/- 2.2 mm. In the multipara group, an average cervical length of 40.1 mm +/- 7.4 mm, a thickness of 29.3 +/- 3.9 mm, an internal os of 5.1 +/- 2.6 mm, a cervical canal of 4.3 +/- 1.3 mm and an external os of 5.8 +/- 1.8 mm were found. Contrary to our expectations, there was no statistically significant difference between the two groups. Furthermore we did not find any correlation between the internal and the external os.

Cervix Uteri↗
PubMed1992

[Latent cervical virus infection as a possible cause of early abortion].

Cervical smears of 50 women who had an abortion were examined by dot-blot hybridization for human papillomavirus (HPV), herpes simplex virus (HSV) types 1 and 2, and cytomegalovirus (CMV) DNA. HPV DNA type 16 or 18 positivity was shown in 17.6% of the cases; in the aborted material, however, it amounted to 30.8%. IgM-positive titres were present in a few cases. In cervical smears of intact pregnancies, positivity for HPV DNA types 6 and 11 was detected in 9.5% and for the HSV DNA types 1 and 2 and CMV DNA in 48.0% of the cases. In this group of patients mostly positive IgM and IgG titers were present.

Abortion, Spontaneous↗
PubMed1992

[Effect of high performance sports on female menstrual cycle exemplified by windsurfing].

Questionnaires were sent to all female members (n = 60) of the Austrian Funboard Association (funboard = the most athletic windsurfing class). They included questions about the menstrual cycle, physical capacity, libido and performance dependent on the particular cycle phase. There was no significant libido or capacity peak, neither for the windsurfers nor for a normal collective (n = 100); on the other hand there was an evident low during menstruation. A mean length of the menstrual cycle of 26.5 +/- 2.8 days and a bleeding time of 4.4 +/- 1.2 days were found, while metrorrhaghia and dysmenorrhea were less frequent than in the normal collective. One reason for these findings could be that physical activity reduces dysmenorrhea.

Adult↗
PubMed1992

[C-erbB-2 oncogene amplification in breast cancer in correlation to steroid and epidermal growth factor receptor].

The amplification grade of oncogene c-erbB-2 was examined by the polymerase-chain-reaction-method in DNA's of 56 primary mammary carcinomas. 26 (46.4%) of these showed the amplified oncogene c-erbB-2. In the strongly amplified cases, the expression of the c-erbB-2 oncoprotein was verifiable immunohistochemically. Between the progesterone receptor status (PR) and the amplified c-erbB-2 oncogene there was a statistically proven dependency. No correlation was observed between the amplified c-erbB-2 oncogene and the epidermal growth-factor receptor (EGFR).

Biomarkers, Tumor↗
PubMed1991

[Vaginal sonographic imaging of the ovula Nabothi].

Twenty patients, showing retention cysts in vaginosonographic examination, were included in our study. We differentiated between superficial and deep located Nabothian cysts. Fourteen cases showed primarily visible superficial cysts, the other six could only be detected vaginosonographically. The Nabothian cysts varied in size from 4 to 26 mm, the average diameter was 13 mm. Only four cases showed solitary Nabothian cysts, the other sixteen cases were multiple. The clinical significance of Nabothian cysts in the field of sterility diagnostics, especially the deep located retention cysts, cannot be assessed at present.

Adolescent↗
PubMed1991

[Color Doppler flow measurements in uterine cancers].

Pulsed Doppler Flow Measurements in patients suffering from collum cancer using a coloured pulsed Doppler technique measurements of blood flow of the uterine artery were performed in a group of 35 patients suffering from an inoperable collum cancer (stage II and III according FIGO) and compared with a collective of 30 healthy women with normal anamnesis. The mean pulsatility index (PI) was significantly lower in the sick group (stage II 1.6 +/- 1.17, stage III 0.76 +/- 0.21) than in the healthy group (PI = 3.18 +/- 0.99) (p less than 0.01). In 14 subjects of the last group there was no significant difference in PI between the left and right uterine artery (left: PI 2.81 +/- 0.83), right: PI 2.78 +/- 0.76).

Adult↗
PubMed1991

[Comparative study of introital sonography and the urethrocystogram in women before and after surgery for stress incontinence].

In a prospective study of sonographic and radiographic methodologies we compared morphologic bladder data in 30 patients before and after stress incontinence surgery. 18 women were subject to colposuspension according to Burch due to recurrent stress incontinence, 12 women underwent anterior colporrhaphy. Visualisation of bladder, urethra and beta-angle was adequate with both methods. The good visualisation of the anatomical and functional situation of the vesico-urethral area is a major benefit of introital sonography.

Adult↗
PubMed1991

Ultrasonic Doppler flow studies of the uterine arteries in women with cervix cancer.

The main characteristic of malignant tumors is their capacity for local destructive spread as well as infiltration into the adjacent tissue. The present study was carried out to evaluate the hemodynamic alterations in patients with advanced cervix cancer. Data of 34 patients with cervix cancer are compared to 30 healthy women with normal history. The mean pulsatility index (PI) was significantly lower in cancer patients (PI = 1.75 +/- 1.27) than in controls (PI = 3.18 +/- 0.99). Use of noninvasive Doppler ultrasound study physiology of uterine hemodynamics in patients with cervix cancer is of great clinical relevance and paves the way for further investigations in screening programs for cervix cancer.

Arteries↗
PubMed1990

Early detection of ectopic pregnancy by transvaginal ultrasound.

Transvaginal (TVU; 19 patients) and transabdominal ultrasound (TAU; 24 patients) were compared in their ability to visualize an ectopic pregnancy. The direct visualization of ectopic pregnancy (EUP) was 25% with TAU and 94.7% with TVU. All women had a proven EUP in laparoscopy. TAU approach showed a significant inferiority (P less than 0.02) and TVU a superiority (P less than 0.08) in comparison to clinical examination. 83% of 43 women had spotting. Nonspecific signs for EUP like fluid in the pouch of Douglas was seen in 20.9%. Thin endometrium was seen in 6.9%, in 37.2% the thickness of endometrium was under 10 mm, in 55.8% more than 10 mm. An intrauterine pseudogestation sac was detected in 6.9%, corpus luteum formation in 37.2%.

Adult↗
PubMed1990

[Gynecologic Doppler ultrasonography].

The resistance of the vessel of the ovarian artery changes during the cycle. At the time of ovulation the resistance of the vessel of the ovarian artery decreases under the influence of steroid production in the ovary. The resistance decreases and the blood flow increases. In our study we could show that women with a normal cycle have low pulsatility indices in the ovarian arteries when oestradiol is rising. In women with PCO-Syndrome the blood flow in the ovarian artery is very low in spite of the fact that the patients got hormonal treatment. On the day of follicular puncture in our IVF-group and also on the day before, the pulsatility-index of the ovarian artery was very high in patients with PCO-Syndrome and it was significantly lower in patients with normal cycle. The women with PCO-Syndrome had also low oestradiol levels in the plasma. In the group with PCO-Syndrome no woman became pregnant, women with high oestradiol levels and low PI of the ovarian artery at the time of follicular puncture became pregnant in 19%.

Adult↗
PubMed1990

[Vaginal ultrasound study of the normal and incompetent cervix: attempting a mathematical assessment].

A group of 217 pregnant patients was examined by vaginosonography. The group could be divided into 62 patients with incompetent cervix and 155 patients with normal findings. We measured the width of the internal os, the length and the thickness of cervix of all patients in intervals of 14 days. We registered a dynamic process pattern of cervical, morphological changes in the group with preterm delivery. We tried to reduce these cervical changes to an arithmetic formula.

Adult↗