The protein permeabilities of the blood-cerebrospinal-fluid barrier and the blood-urine barrier are compared. In both instances the permeation rates of proteins can be better correlated to hydrodynamic radii than to molecular weights. The decreasing clearance rates of ceruloplasmin, IgG, and IgA reflect the hydrodynamic heterogeneity of these proteins, which have similar weights. The IgM clearance rate appears too high, possibly owing to monomer IgM, other IgM fragments, selective transport, or active immunity, so its inclusion is not recommended in clearance studies.

Ceruloplasmin↗

PubMed1977

[Pathophysiology and clinical aspects of acute and chronic kidney insufficiency with special reference to operative field].

Explore the source record for details and available documents.

Acidosis↗

PubMed1976

[Sensory and chemical changes of dried foods under the influence of extreme storage conditions. 1. Method of sensory evaluation (author's transl)].

This paper described a method for the evaluation of sensory changes in the quality of dried foods, which have been stored under extreme conditions. The applied method is based on the 5 point DLG-scale, the structure of this scale has been adapted to the requirements of a methematical-statistical evaluation. In addition standard samples are provided as reference during the test.

Animals↗

PubMed1976

[Sensory and chemical changes of dried foods under the influence of extreme storage conditions. 2. Sensory changes (author's transl)].

The sensory quality of dried infant foods is decreasing steadily during the storage under extreme conditions. Odor and taste are influenced to a higher degree than colour and consistency. A package with a high permeability for oxygen and water vapor has an unfavourable effect on the storability. The composition of the investigated products has no influence on the sensory estimation, but a significant influence on the storage behavior.

Animals↗

PubMed1976

The different forms of glomerulonephritis morphological and clinical aspects, analyzed in 2500 patients.

Comparative morphological and clinical studies of 2,500 patients suffering from glomerulonephritis, enabled us to divide the different forms of diffuse glomerulonephritis into 3 distinct groups and to separate these groups from the focal glomerulonephritides. The different forms of diffuse glomerulonephritis in group I are: 1. endocapillary (acute) glomeruloenphritis (of the post-streptococcal type), 2. mesangioproliferative glomerulonephritis, 3. mesangioproliferative glomerulonephritis with focal crescents, 4. mesangioproliferative glomerulonephritis with focal scarring, 5. minimal proliferating intercapillary glomerulonephritis without nephrotic syndrome. It is emphasised that these forms can transform into one another, that they seldom occur with nephrotic syndrome, and with varying frequency with hypertension. Group II consists of: 1. minimal proliferating intercapillary glomerulonephritis with nephrotic syndrome, 2. focal sclerosing glomerulonephritis, 3. perimembranous glomerulonephritis, 4. membranoproliferative glomerulonephritis, 5. lobular glomerulonephritis. It is stressed that these glomerulonephritis forms usually do not develop out of group I type glomerulonephritis forms, and that in this group a nephrotic syndrome is the most prominent clinical syndrome. In the third group are 1. mesangioproliferative glomerulonephritis with diffuse crescents, 2. necrotising glomerulonephritis. It is shown that this form of glomerulonephritis does not usually develop from either group I of II forms. The fourth group of focal glomerulonephritis is uncommon. This disease is characterized by a necrotising and proliferative inflammatory lesion found segmentally and focally in the glomeruli. Most of the other glomeruli appearing normal. It is emphasised that in the literature the diagnosis focal glomerulonephritis is made far too often. This is because glomeruli in which the inflammatory process in a few lobules is of varying prominence, are included in the focal glomerulonephritis group. The classification of the different forms of glomerulonephritis into 3 groups here described, is thought of as a basic classification. It is compared with Ellis' classification (1942), with which it has much in common.

Basement Membrane↗

PubMed1976

[The evaluation of test panel members with the tetrade-test. Short notice to the contribution of Miller, Schmidt and Wildbrett (author's transl)].

For the application of the tetrade-test in the evaluation of sensory test panel members some principles are mentioned and some interpretations are given.

Food Inspection↗

PubMed1976

[Sensory and chemical changes of dried foods under the influence of extreme storage conditions. 3. Chemical changes (authors transl)].

The content of free amino acids and free fatty acids of dried infant foods is clearly decreasing during the storage under extreme conditions, whilst the percentage composition of the fatty acids in the triglycerides remains nearly unchanged. The content of hydroxymethylfurfural is connected with the sensory changes. For the single foods as well a high increase as a strong decrease of the HMF-content can be combined with distinct sensory changes. The vitamin C-content decreases during the storage, the permeability of the packing material for oxygen and water vapor has an unfavourable effect. Furthermore the pH-value of the investigated products is lowered during the storage period.

Amino Acids↗

PubMed1976

[Sensory and chemical changes of dried foods under the influence of extreme storage conditions. 4. Flavor compounds (authors transl)].

From dried infant foods stored under extreme conditions aroma compounds have been isolated analyzed by gas chromatography and mass spectrometry. The results has been, that during the storage long chain aliphatic aldehydes are newly formed.--It is scarcely possible to attach the investigated chemical parameters (content of ascorbic acid, free amino acids and free fatty acids, hydroxymethylfurfural, pH-value) for the investigated products to a sensory impression.

Amino Acids↗

PubMed1975

[Pre-renal failure due to villous adenoma of the colon].

A 68-year-old man with known villous adenoma of the rectum had recurrent severe episodes of dehydration and electrolyte loss, misinterpreted as being due to "chronic pyelonephritic". The dehydration proved, in fact, to be due to the adenoma and ceased after removal of the tumour.

Acute Kidney Injury↗

PubMed1975

Clinical value of the renal protein clearance determination.

The clinical applicability of the determiniation of selectivity in proteinuria in the traditional way is limited. The methodological apparatus has to be relatively completed to get predicative results. Simplified procedures, e.g. determination according to two proteins only, have not proven to be useful in our hands. Screening tests such as disc electrophoresis have to precede the determinations. In special clinical problems, e.g. the question of steroid sensitiveness in morphological forms of glomerulonephritis, which supposedly do not respond to steroids according to the results of prospective studies, or as a parameter in observing the follow up of a disease, protein clearances may be a valuable diagnostic help.

Adolescent↗