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Biomedical subjects

E Ring-Mrozik

Publications and source records attributed to E Ring-Mrozik.

16 recordsLinked to original sources

Tracheal stenosis by innominate artery compression in infants: surgical treatment in 35 cases.

This is a report on 35 cases of innominate artery compression of the trachea and its surgical correction by means of aortotruncopexy. Diagnostic procedures of choice were tracheoscopy and magnetic resonance imaging, which offers representative images of inspiration and expiration, shows the anatomical relations between aortic arch and trachea and reveals the extent of tracheal compression. Surgical treatment is indicated if narrowing of the tracheal lumen exceeds 70%. By fixation of the aortic arch and the proximal innominate artery to the back of the sternum, tracheal compression is relieved. There was no unsuccessful operation in the 35 children. One late death occurred from cardiac failure, unrelated to tracheal compression.

Aorta, Thoracic

Indication and results of thoracic surgical procedures in premature infants.

This analysis concerns three groups of malformations: Congenital diaphragmatic hernia, patent ductus arteriosus, and oesophageal atresia. We registered a total mortality rate for all congenital diaphragmatic hernias and defects of 28.5%; the rate in full-term neonates was 27.6% and in premature infants 33.6%. Of 65 infants with a patent ductus arteriosus and a birth weight less than 1500 g, 14 died (21.5%). In most cases death was caused by sepsis. Among the 159 patients with oesophageal atresia who were treated in our hospital, 58 were premature infants. During the last 20 years, the total mortality rate among our patients was 28.9%. We had a mortality rate of 44.8% in premature infants and of 19.8% in full-term neonates. An analysis of the last 10 years showed a survival rate of 97% in healthy infants (group A in Waterston's classification). In group C, the most disadvantageous group (premature infants, severe anomalies), the rate was 61%.

Ductus Arteriosus, Patent

Clinical findings in middle lobe syndrome and other processes of pulmonary shrinkage in children (atelectasis syndrome).

Processes of atelectasis and pulmonary shrinkage are not confined to the right middle lobe. This fact is illustrated by case reports of five of our nine such patients. All cases shared common clinical and morphologic similarities: congenital malformations of the bronchial skeleton, compression, and chronic inflammation produce comparable pulmonary morphology that always includes atelectasis. Atelectasic processes of longer duration require surgical resection; this led to cures in all the authors' patients.

Bronchiectasis

[Tracheal compression by the brachiocephalic trunk in infants--surgical treatment of 30 cases].

This is a report on 30 cases of innominate artery compression of the trachea and its operative correction by an aorto-truncopexy. Tracheoscopy is the most important examination for arriving at the diagnosis. Magnetic resonance imaging (MRI), which offers representative pictures of many moments of expiration and inspiration, shows the anatomic relationship between the innominate artery, the aortic arch and the trachea, also demonstrating the extent of the tracheal compression. Surgical treatment is indicated if narrowing of the lumen of the trachea is greater than 70%. By fixing the aortic arch and the proximal innominate artery at the back of the sternum the trachea is relieved of its compression. In 30 children there was no unsuccessful operation, and none of them died.

Aorta, Thoracic

The Dandy-Walker syndrome.

Ten cases of the Dandy-Walker syndrome are presented. The clinical manifestations are analyzed. Almost 80 percent of these children had associated anomalies. The characteristic findings are based on the magnetic resonance image scan. Satisfactory treatment of our patients had mostly consisted in shunting the lateral ventricular system to the peritoneum. The incidence of the complications was high.

Abnormalities, Multiple

[Intraoperative sonographic diagnosis of the ventricular position of shunt systems in infants with hydrocephalus].

Intraoperative ultrasound is performed in hydrocephalic newborn who were undergoing placement of a ventriculoperitoneal shunt. It is possible to show intraoperatively the tip of the ventriculoperitoneal shunt tube. By this method the optimal positioning of shunt tube is assured and the postoperative complication rate may be reduced. The use of this method is demonstrated by case reports.

Cerebral Ventricles

[Experimental studies of the small intestine mucosa].

The problems pertaining to the surgical therapy of the short bowel syndrome have not yet been solved despite numerous methods for the retardation of stool passage and the enlargement of the absorbent small intestinal surface. We therefore developed a model for the cultivation of neomucosa of endogenous origin on the perietal peritoneum of Wistar rats. In 191 young Wistar rats of each sex with a body weight of 200 to 500 grams, a loop of the small intestine was largely blocked off from the intestine with the help of Braun's anastomosis, opened up and thus sewed onto the parietal peritoneum of the laboratory animal. This led to the formation of a tube with two-thirds of the circumference consisting of small intestine and one-third of peritoneum. After the peritoneal part had been over-grown by neomucosa, the original jejunal part was removed and a tube consisting of perietal peritoneum with a muscular portion was formed around the neomucosal island. After another 4-5 months, a mucosal tube with complete neomucosal lining had formed. It was demonstrated by histological, enzyme histochemical and electron microscopy methods that the neomucosa is indeed a functioning small intestinal mucosa. Intragastric administration of a prostaglandin E2 analogue resulted in accelerated neomucosal growth as well as an increase in the height of the villi and the depth of the cryptae and a decrease in the thickness of the granular tissue. Measurements of the accumulation of 14C glucose and its inhibition by ouabain confirmed the active transport of the 14C glucose in the cell of the small intestinal neomucosa. The cultivation of functioning small intestinal mucosa on the perietal peritoneum of rats was thus accomplished.

Animals

[Correction of subtotal esophageal aplasias and extensive artificial esophageal defects by gastric transposition].

The successful treatment of subtotal oesphageal defects by means of gastric transposition in three children is reported. Two children had a subtotal oesophageal aplasia, one a complete destruction of more than half of the thoracic oesophagus. In two cases the stomach was transposed into the physiological oesophageal bed, in the third the stomach was pulled retrosternally to the cervical region via the anterior mediastinum. All three children developed normally following gastric transposition. Normal oesphageal passage was confirmed radiologically.

Child, Preschool

[Results of follow-up of operations in pediatric patients with indirect inguinal hernia].

This paper present the results of follow-up examinations of 2801 operated inguinal hernias. In comparison with the high excision of the hernial sac plus "crude suture", the standard Bassini technique produces poorer results as regards recurrence, testicular atrophy and secondary maldescent. The mortality of elective herniotomy was 0.016% in this series.

Atrophy

[Vesico-intestinal fissure with meningocystocele--attempt at clarifying an embryologic connection].

The treatment of a boy is reported, who suffered from a combination of vesico-intestinal fissure and meningocystocele. Because five of seven patients known to us since 1969 had a similar combination, it should be analysed whether there exists an etiological or embryological connection. Therefore the pertinent literature and clinical data of known patients was collected and evaluated. It can be shown that also in the literature a coincidence of 75% of vesico-intestinal fissure and meningomyelocele is reported and both are caused during the 4th week of embryological development. Vesico-intestinal fissure is a disturbance of mesodermal inflow into the lower abdominal wall. The cause for meningocystocele is an abnormal cell proliferation of the neural anlage. Despite a number of possible clues an etiological connection could not be proved.

Abnormalities, Multiple

[Therapy of postoperative complications following abdominoperineal or abdominosacroperineal pull-through surgery in anal atresia].

In 144 pull-through-operations performed for anorectal-atresia, following complications were observed: pneumonia 11%, sepsis 8.3%, peritonitis 5%, bowel obstruction 5%, osteomyelitis 1%, retraction of the pulled-through colon 4%, anal stenosis 16%, secondary megacolon 9%, fistula relapse 8%, mucosal prolapse 4%. Recto-urethral, recto-vesical- and recto-vaginal fistula relapses are managed by interposition of the gracile muscle. Anal stenoses and secondary megacolon are prevented by a sufficiently long postoperative bougienage.

Anus, Imperforate

Magnetic resonance imaging in children suffering from spina bifida.

22 children with myelomeningocele (MMC) were examined by magnetic resonance imaging (MRI). After operative closure a tethered cord was found in 78% of the patients. A primary tethered cord was detected in all patients where a lipomyelomeningocele had not been operated on yet. Additional malformations shown by MRI were hydromyelia and diastematomyelia. No correlation could be found between the degree of morphologic changes and the clinical course. In covered MMCs, MRI investigation is recommended as method of choice before operation. After operative closure a control-MRI should be performed after three months. If there are no pathological findings, further follow-up should be done by ultrasound investigation twice a year.

Adolescent

Historical aspects of hydrocephalus.

From early days on physicians took interest in hydrocephaly because of its grotesque appearance. Already Hippocrates recommended decompression-trepanation for the treatment of hydrocephalus. Only since anatomy and pathophysiology of hydrocephalus as well as production and absorption of the cerebrospinal fluid was clarified, more effective operative techniques could be developed. Conservative treatment was unsuccessful or was useful only as temporary or adjuvant therapy supporting surgical procedures. A great variety of operative methods was described since the middle of 19th century which yielded, however, unsatisfactory results in most instances. Results improved since the introduction of effective valve systems in combination with ventriculoatrial and ventriculoperitoneal shunts. Despite of improved results, the treatment of hydrocephalus remains problematic as is shown by the still high complication rate and the restless search for more effective ways of treatment.

Bibliographies as Topic

[The value of C-reative protein analysis for the differential diagnosis of non-acute appendicitis].

Appendicitis is one of the most common causes for laparatomy in children. Diagnosis can be very problematic, especially if appendicitis is combined with gastro-enteritis. Furthermore, difficulties can be encountered in diagnosis of diseases such as mucoviscidosis, leukosis, immunosuppressive or chemotherapy are present. In addition to the common clinical examination we have to look for other methods to complete the indication for appendectomy. Therefore in 1985 we added the CRP-determination to our diagnostics for patients with suspected appendicitis. In a retrospective study 269 patients who had signs of acute appendicitis were examined. We found that the determination of the CRP-level, in conjunction with the standard parameters of appendicitis, represents a valuable addition to the diagnostic armamentarium. However our data shows, that the CRP-level in itself cannot be regarded as a sole criteria for an unambiguous diagnosis of non-acute appendicitis, as it is the case with any other appendicitis parameter.

Acute Disease