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Biomedical subjects

E Roa

Publications and source records attributed to E Roa.

11 recordsLinked to original sources
PubMed1991

The effect of doxazosin on platelet aggregation in normotensive subjects and patients with hypertension: an in vitro study.

An in vitro assay was used to investigate the effects of doxazosin on the platelet aggregation induced by epinephrine, collagen, and adenosine diphosphate. Platelet-rich plasma from normotensive subjects and patients with hypertension was compared. Doxazosin produced a concentration-dependent inhibition of platelet aggregation in both groups, but significantly lower concentrations were required to inhibit platelet aggregation in plasma taken from patients with hypertension. The concentrations of doxazosin that inhibited platelet aggregation in vitro were similar to those that are used clinically to control blood pressure in patients with hypertension.

Adult↗
PubMed1991

[Colposuspension in the treatment of stress urinary incontinence: long-term yield].

Surgery in 227 cases of urinary stress incontinence (USI) associated to other abdominal and/or vaginal pathologies, by means Burch colposuspension, has given a success rate of 90.3% recovery of USI 6.6% improved urinary incontinence grade, an 98.3% recovery rate of the concomitant genital prolapse, in a follow-up period mean of 42 moths. Postoperative complication of the surgical procedure are analized.

Adult↗
PubMed1987

[Gynecomastia].

Explore the source record for details and available documents.

Adolescent↗
PubMedDate not supplied

[Interaction of cimetidine and metoclopramide on the lower esophageal sphincter in man].

The purpose of this study is to evaluate the effect of Cimetidine and Metoclopramide on human lower esophageal sphincter (LES) pressure. Intravenous Metoclopramide in a bolus injection (0.3 mg/Kg or a maximal dose of 20 mg) produced an increase of LES pressure from 20,8 +/- 3,1 mmHg to a peak response of 42,0 +/- 5,0 mmHg. Intravenous Cimetidine in a bolus injection of 300 mg failed to alter basal LES pressure and LES response to Metoclopramide. Cimetidine in continuous infusion (100 mg/h) also failed to alter basal LES pressure and LES response to intravenous Metoclopramide. These studies suggest that: (1) Human LES pressure increases in response to intravenous Metoclopramide; (2) H2-Antagonism with Cimetidine has no effect on the human LES basal pressure; and (3) The H-2 receptors have no apparent role in the human LES response to Metoclopramide.

Adult↗