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Biomedical subjects

E Rossipal

Publications and source records attributed to E Rossipal.

At least 37 records · Page 2Linked to original sources
PubMed1980

The prognosis of idiopathic nephrotic syndrome: a comparative study between the index of selectivity of proteinuria and the findings in renal biopsies.

In 20 children with idiopathic nephrotic syndrome, the morphological changes in the glomeruli were compared with the index of selectivity of proteinuria. For the determination of the index of selectivity, the clearances of IgG and transferrin were used. A high correlation was found between the morphological changes and the index values. An index of selectivity of proteinuria of 0.20 proved to be the critical value for differentiating between a steroid sensitive and a steroid resistant INS.

Child↗
PubMed1979

[Loss of inhibitors of the blood coagulation system in protein-losing enteropathy (author's transl)].

The investigation of the haemostasis of a 11 6/12 years old boy with protein-losing enteropathy revealed signs of hypercoagulability of the coagulation system, due to a decreased plasma concentration of antithrombin III and alpha1-antitrypsin, that were lost with other proteins in great amounts into the intestinal tract. The loss of these two important inhibitors of the coagulation system can lead to thrombotic complications in patients with protein losing enteropathy.

Antithrombin III↗
PubMed1979

Immune disturbances after severe enteritis during the first six months of life.

Infants with severe enteritis and associated prolonged thymic atrophy during the first six months of life showed persistent cell-mediated immune deficiency between the ages of three and five years. Experimental investigations show that early intrauterine and extrauterine stress may lead to permanent cell-mediated immune deficiency and an imbalanced immune response. Trends in disease frequency among different population groups may be influenced in part by the immunity of the host.

Animals↗
PubMed1978

[Determination of faecal fat in infants and children with bacterial and viral infections (author's transl)].

In 100 infants and children with bacterial or viral infections determination of faecal fat was done. None of the patients showed signs of malabsorption prior to investigation. The faecal fat content is expressed as percent of the dry weight of the stool. A fat content of up to 14% of the dry weight of the stool can be regared as normal. A faecal fat content of 15 to 20% is indicative for an elevated fat excretion, and a fat content of more than 20% gives evidence for steatorrhoea. In 80% of the infants with bacterial and in 50% of the infants with viral infections steatorrhoea could be demonstrated. In children with bacterial infections 18% showed a normal, 69% an elevated fat excretion ain 13% there was a steatorrhoea. In children with viral infections 6% showed a normal fat excretion whereas 81% had an elevated excretion and 13% exhibited steatorrhoea. Thus viral infections compared with bacterial infections seem to cause disturbances of fat absorption more frequent. Whereas the degree of the disturbance seems ot be less intense in viral infections.

Bacterial Infections↗
PubMed1977

[Immunologic development disorders and disease incidence].

Interference with any organ system during development leads to permanent damage. Severe disease or starvation during the first four months of extrauterine life lead to a persistent deficiency of cell mediated immunity, which changes the life expectancy and later disease patterns in population groups. Severe intercurrent disease, starvation or trauma later in life lower cell mediated immunity only temporarily.

Allergy and Immunology↗
PubMed1976

Steatorrhea, a simple and rapid method of diagnosis.

A simple and rapid method for the diagnosis of steatorrhea is described. The method is based on the assessment of the difference of specific gravity and lipophilic property between a normal stool and that in steatorrhea, using a benzene-NaBr system. The stool samples are dried, pulverized, and then investigated. Steatorrhea is defined either as a fat or more in a 24-hour sample. Stool samples of 71 infants and children were examined. Among these were 23 healthy subjects, 10 with upper respiratory tract infections, and 6 with pneumonia. A further 31 children had celiac disease, 9 of them were on a gluten-free diet, and one child had cystic fibrosis. The procedure described renders single stool samples suitable for the assessment of steatorrhea. As a screening test the method proved to be rapid and accurate in the diagnosis of steatorrhea.

Adolescent↗
PubMed1976

Persistent cell mediated immune-deficiency following infantile stress during the first 6 months of life.

The cell mediated immunity as expressed by 2,4 DNCB skin sensitivity was measured in 50 healthy Iranian orphans of the age from 15 years. Complete records of the development of these children from birth were available. Children with severe gastroenteritis leading to marasmus and temporary thymic atrophy during the first 6 months of life showed a persistent atopy 1-5 years later. Less severe disease during this time lead to hyporesponsiveness. Similar stress after the 6th month of life did not lead to persistent changes in their cell mediated immunity. The implications of this for the epidemiology of neoplasia and infectious disease are discussed.

Age Factors↗
PubMed1976

[Human urinary fluoride excretion at various ages (author's transl)].

3 groups, each consisting of 5 subjects in the following age ranges (A 4 to 6 years, B 25 to 45 years, C 60 to 70 years) were given fluoride in the form of a single dose of 6 mg. Fluoride excretion in the urine was subsequently investigated over a period of 24 hours. In a second experiment a daily dose of 6 mg of F- was given to the 3 groups over a period of 10 days. The urinary excretion was determined in 24-hour urine samples. The results are presented in two figures. 1. A time drift in urinary fluoride excretion in the direction of delayed fluoride metabolism was seen in group C subjects. 2. A periodic increase in the urinary fluoride values was also seen in these elderly subjects, indicative of an altered regulatory mechanism.

Adolescent↗
PubMed1976

[Considerations regarding the influence of intrauterine and early postnatal diseases and nutritional deficiencies on immunity and disease epidemiology (author's transl)].

Malnutrition, infectious and toxic stress, hormonal and enzymatic deficiencies as well as graft versus host reactions during the last trimester of pregnancy and during the first six months of life lead to persistent depressions of cell mediated immunity. The subsequent imbalance between the cell mediated and humoral system of immunity leads to differences in disease prevalence in poor and rich populations. Particularly leprosy, tuberculosis, viral disease as for instance frequently fatal measles and diseases due to complexes between humoral antibody and bacterial components as for example acute rheumatic fever occur with increased frequency in B (+) T (-) populations. Desturbances of immune surveillance due to suppression of specific cell mediated immune function leads to an increased frequency of neoplasia, particularly B-cell lymphoma and gastrointestinal tumors. Populations in which the T-cell system can mature without interference show a trend towards diseases in which excessive T-cell response plays a major role, as for instance rheumatoid arthritis, Sjögren syndrome, terminal ileitis, autoimmune angiopathies, multiple sclerosis and possibly also disseminated lupus erythematodes.

Autoimmune Diseases↗
PubMed1975

[Incidence of coeliac disease in children in Austria (author's transl)].

The incidence of coeliac disease in infants and children was estimated by the number of children born between 1 January 1969 and 31 December 1972 and the number of patients with coeliac disease born during the same period in the area served by the Kinderklinik Graz. The drainage area of the Kinderklinik Graz comprises 10.5% of the population of Austria and 11.1% of the children born in Austria during the period mentioned. The diagnostic criteria for coeliac disease includes evidence of intestinal malabsorption, a subtotal atrophy of the duodenojejunal mucosa and the demonstration of clinical and biochemical response to gluten withdrawal. In all patients born in 1972 a second biopsy was done after a period on gluten free diet and a third biopsy after reintroduction of gluten. The incidence of coeliac disease showed to be 1 in 496. The incidence for girls proved to be 1 in 403 and that for boys 1 in 636. These figures are in good correlation to that reported for Ireland and Switzerland but much higher than those estimated for Britain.

Austria↗