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E S Amin

Publications and source records attributed to E S Amin.

7 recordsLinked to original sources
PubMed1980

Comparative study of the effect of oral contraceptives containing 50 microgram of estrogen and those containing 20 microgram of estrogen on adrenal cortical function.

Because the adrenal cortex is an endocrine gland essential to life, its function was studied in women who were taking an oral contraceptive that contained either 50 microgram or 20 microgram of estrogen. Of 32 healthy women studied, 18 used an oral contraoceptive that contained 50 microgram of estrogen, and 14 used an oral contraceptive that contained 20 microgram of estrogen. With 50 microgram of estrogen, the total plasma cortisol level rose significantly, the level of urinary cortisol excretion did not change significantly, and the levels of 17-ketosteroids and 17-ketogenic steroids were significantly reduced. With 20 microgram of estrogen, there were no significant changes in the levels of total plasma cortisol, urinary cortisol excretion, and the excretion of 17-ketosteroids and 17-ketogenic steroids. Thus, adrenal cortical function was altered in women who used an oral contraceptive that contained 50 microgram of estrogen, but there was no significant effect with the use of an oral contraoceptive that contained only 20 microgram of estrogen. Our findings confirm previous ones in regard to the effects of 50 microgram of estrogen on adrenal cortical function, although no studies had been carried out previously on the effects of 20 microgram of estrogen.

17-Ketosteroids↗
PubMed1980

Effect of gelatin infusion on urinary excretion of water and electrolytes in rats.

The effect of gelatin infusion on water and electrolyte excretion in urine was studied by measuring the volume of excreted urine and the urinary excretion of Na+, K+, Ca++ and Mg++ in a group of male rats before and after receiving infusions of a 5% autoclaved gelatin solution containing 1% glycine (1 ml/100 g body). A similar group of rats received the diluent only (control group). The results obtained showed that the diluent had a diuretic and natriuretic effect but with a less marked degree than gelatin solution which caused marked diuresis, natriuresis and increased excretion of Ca++ and Mg++ in the urine. The K+ excretion was significantly decreased following gelatin infusion. All of these measurements returned to the base-line level after 72 h following gelatin infusion.

Animals↗
PubMed1977

The fate of intravenously infused gelatin.

The fate of i.v. infused gelatin was studied by measuring the rise in the level of total hydroxyproline (HP) in some organs of the rat following the infusion of a 5% autoclaved gelatin solution (1 ml/100 g body weight). The results obtained showed that HP levels were consequently increased in all of the organs studied, then the levels were generally normalised during the 3rd day post infusion. Small concentrations of HP were still retained by the kidneys and blood plasma, at the end of the first week after infusion. The rat ratio HP/creatinine (HP/C index), which increased from 0.33 to 3.78 during the first 24 h post infusion, declined gradually to the base-line level after 4 weeks, during which time 94% of the HP infused could be accounted for in the urine. Most of the HP was excreted in the bound form.

Animals↗
PubMed1975

Effect of human plasma lipase on smooth muscle.

In the presence of serum albumin, the enzyme human plasma lipase produces a slow contraction of smooth muscle. This effect was not antagonized by antazoline or by atropine, and was completely abolished by heating the enzyme prepartion for 1 min at 60 degrees C. Calcium ions were found to potentiate the effect of plasma lipase on smooth muscle.

Animals↗