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Biomedical subjects

E S Mach

Publications and source records attributed to E S Mach.

At least 37 records · Page 2Linked to original sources

[Place of hemocarboperfusion and hyperbaric oxygenation in the treatment of patients with rheumatoid arthritis with systemic symptoms].

Altogether 12 patients were treated by the hemocarboperfusion method and 20 patients with systemic symptoms by the hyperbaric oxygenation (HBO) method. Positive results were obtained and it made it possible to recommend the above methods for multimodality therapy of patients with rheumatoid arthritis with systemic symptoms. A severe, rapidly progressive course of rheumatoid arthritis with the development of various systemic symptoms, a high titer of the rheumatoid factor should serve as an indication for hemocarboperfusion. HBO is found appropriate in such systemic symptoms as ischemic polyneuropathy, digital arteritis, trophic ulcers and Raynaud's syndrome.

Adult

[Status of tissue microcirculation in psoriatic arthritis].

Microcirculation (the skin and skeletal muscle) was studied using a method of 133Xe clearance from the interstitial depot in 35 patients with psoriatic arthritis. It showed significant microcirculatory disorders expressed in a statistically significant decrease in the effective cutaneous blood flow in unaffected skin zones (mostly in women and in a high inflammatory activity of the process) and in the muscular microcirculation especially noted in the period of reactive hyperemia. The results obtained indicate the presence of generalized involvement of the microcirculatory bed vessels in psoriatic arthritis.

Adult

[Corinfar in the treatment of Raynaud's syndrome in systemic scleroderma (preliminary results)].

Twenty patients with systemic scleroderma (SSD) and Raynaud's syndrome (RS) received 30-80 mg of corinfar, a blocker of calcium channels, during 14 days. Seventeen patients responded to the treatment. The clinical effect was manifested by a decrease in the rate, duration and intensity of RS attacks. Side effects were recorded in 6 patients, but the drug was discontinued only in 2 patients because of the allergic reactions. During treatment, the patients showed an increase in tissue blood flow parameters. Corinfar may be regarded a drug of choice in the treatment of marked RS in SSD.

Adult