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Biomedical subjects

E S Malbran

Publications and source records attributed to E S Malbran.

At least 19 recordsLinked to original sources
PubMed1993

Closed-system phacoemulsification and posterior chamber implant combined with penetrating keratoplasty.

The main intraoperative difficulties of performing a procedure combining open-sky extracapsular cataract extraction, implantation of posterior chamber intraocular lens (PC-IOL), and penetrating keratoplasty ("triple procedure"), most frequently caused by the uncompensated posterior pressure created when the cornea is open, include incomplete capsulorhexis, incomplete aspiration-irrigation of the cortex, uncertain placing of the IOL, posterior capsule rupture, choroidal effusion, and even expulsive hemorrhage. We recommend a two-step procedure that eliminates these problems: The first step begins with removal of epithelium, half-thickness trephining of the cornea, and capsulorhexis; proceeds through phacoemulsification and aspiration-irrigation; and ends with implantation of the PC-IOL, using a pressurized system. The second step is penetrating keratoplasty. In the six cases undergoing this procedure, none of these complications developed or even tended to develop. Although the follow up in these six cases is very short (from 1 to 6 months), the advantage of the technique is that it effectively precludes the above mentioned intraoperative complications, which could affect late results.

Aged↗
PubMed1991

Vitreoretinal surgery performed through a 60-diopter lens.

For vitreoretinal surgery, we recommend using a 60-diopter lens for indirect ophthalmoscopy through the operating microscope without internal illumination. This device has undergone extensive clinical testing since 1986 with excellent results.

Humans↗
PubMed1989

Genetic spontaneous late subluxation of the lens. A study of two families.

Patients with genetic spontaneous late subluxation of the lens may present signs and symptoms other than lens displacement due to secondary anatomic alteration of the anterior segment. Two families are described, one of them with affected individuals in five successive generations. The vast majority of the patients sought consultation because of progressive myopia or intermittent acute intraocular hypertensive crisis which obscured the basic condition. Upon recognition of the disease, the affected patients underwent an uneventful intracapsular extraction. Histopathologic examination of the removed lenses suggested a dysplastic development of lens zonules.

Adult↗
PubMed1988

Clinically atypical granular corneal dystrophy with pathologic features of lattice-like amyloid deposits. A study of these families.

Four patients from families in Pennsylvania, Massachusetts, and Argentina were diagnosed clinically as having granular dystrophy. Results of pathologic examination of the corneal buttons from each patient after penetrating keratoplasty confirmed granular deposits in the anterior third of the stroma. Amyloid was demonstrated within some of these granular deposits by Congo red staining with birefringence and dichroism and by electron microscopy. In addition to the morphologically granular deposits, numerous fusiform deposits identified as amyloid by histochemistry and electron microscopy and morphologically identical to those seen in lattice corneal dystrophy were detected deep to the granular deposits. It was further shown that the histochemical pattern of staining of the granular material by a series of lectins was similar to that present in corneas with lattice dystrophy. Although a relationship between these patients cannot be definitively proven, each family traces its origins to the Italian province of Avellino.

Adult↗
PubMed1988

Atypical corneal dystrophy with stromal amyloid deposits.

Corneal dystrophies are distinctive clinically and histopathologically; however, variations do occur. We present two cases of stromal amyloidosis from one family masquerading other corneal dystrophy. The two cases are from a six-generation family with an autosomal dominant corneal dystrophy resembling Reis-Bucklers' dystrophy. In these cases, neither the propositus nor other family members showed typical lattice lines. Light and electron microscopy of the obtained corneal buttons disclosed amyloid stromal deposits. The clinicopathologic correlation of these cases suggests that this family represents a variant of stromal amyloid dystrophies.

Adult↗
PubMed1986

Lens guide suture for transport and fixation in secondary IOL implantation after intracapsular extraction.

The authors, after analyzing the different clinical situations where a secondary IOL implantation is indicated, describe 3 surgical techniques based on a common premise relying on the use of lens guide sutures for transportation or transportation and permanent fixation of the IOL's loops. The transportation sutures makes secondary implantation easier in anterior chamber lenses in technique I. The double purpose of transportation and permanent fixation at the angle permits a safe procedure with anterior chamber lenses in cases with no iris support in technique II and the possibility of sulcus or ciliary body fixation of a J type posterior chamber lens after ICCE in technique III.

Cataract Extraction↗
PubMed1986

Inflamed eye in Marfan's syndrome with posteriorly luxated lens.

A 34-year-old man with Marfan's syndrome complained of redness and pain in the left eye. The right eye had been blind because of untractable retinal detachment. The left eye had had three surgical procedures for retinal detachment, and the lens had been luxated in the vitreous for more than 14 years. Ultrasonography demonstrated the spontaneously luxated lens as the possible cause of the inflammatory reaction. The diagnosis of lens-induced endophthalmitis was confirmed by histopathologic examination of the excised lens.

Adult↗
PubMed1986

Superficial involvement in lattice corneal dystrophy.

Twenty-one corneas with lattice dystrophy were studied histologically to evaluate the magnitude of superficial lesions. The compromise included epithelium disarray and atrophy, degenerative pannus, disruption and absence of Bowman's layers, amyloid deposits, and elastotic deposits. These changes were progressive according to patients' age at time of keratoplasty. Oxytalan fibers, an elastic component, were found in affected corneas. The relation of these fibers to elastotic deposition and abnormal fibrillogenesis in lattice corneal dystrophy is discussed.

Adolescent↗
PubMed1984

Cavitary melanocytoma of the ciliary body.

The clinical and pathologic findings of a patient with an unusual cavitary melanocytoma of the ciliary body are presented. Clinically and with ultrasonography the lesion appeared to have a cystic component. Differential diagnoses included a malignant melanoma or a cyst, and the lesion was excised by iridocyclectomy.

Ciliary Body↗
PubMed1983

Retinoblastoma masquerading as ocular inflammation.

The clinical and pathologic findings of a 9-year-old girl with retinoblastoma masqueraded as atypical intraocular inflammation are presented. Histopathologic study revealed a diffuse infiltrating retinoblastoma with seeding of tumor cells into the vitreous cavity and anterior chamber. In tumors with this growth pattern, ultrasonography is of little value. Cytologic examination of aqueous and vitreous aspirates may be misinterpreted and should be evaluated carefully. Because of the seeding of tumor cells, lactate dehydrogenase assay is of diagnostic value prior to considering definitive therapy.

Child↗
PubMed1982

Unusual ciliary body tumor. Mesectodermal leiomyoma.

A 23-year-old white woman presented with a pigmented ciliary body mass in the left eye. The tumor appeared to transilluminate when observed with indirect illumination. Clinically the tumor was considered to represent either a malignant melanoma or a cyst and was excised by iridocyclectomy. Electron microscopic examination established the smooth muscle nature of the tumor. The literature on this unusual tumor is reviewed. Furthermore, this report serves to emphasize the value of iridocyclectomy in the diagnosis and treatment of ciliary body tumors.

Adult↗