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Biomedical subjects

E S Vladimirova

Publications and source records attributed to E S Vladimirova.

At least 19 recordsLinked to original sources

[Traumatic hemobilia].

Authors describe experience of diagnosis and treatment of hemobilia at 10 of 743 patients with trauma of liver. At 7 patients hemobilia was due to closed trauma, and at 3--due to injuries. For diagnosis of hemobilia the USE, Doppler examination of hepatic vessels, esophagogastroduodenoscopy, selective angiography of liver were used. Selective embolization was effective at 7 of 8 patients. Hemobilia has been cured conservatively at 2 patients. Two patients died. It is concluded that complex examination including dopplerography of hepatic liver, esophagogastroduodenoscopy, selective angiography is necessary for diagnosis of traumatic hemobilia. Traumatic hemobilia must be suspected at patients with symptoms of gastrointestinal bleeding in postoperative (posttraumatic) period, and diagnosis of other sources of bleeding does not exclude hemobilia. Selective angiography and embolization of afferent arterial branch is the most effective and safe method of traumatic hemobilia treatment.

Adolescent↗

[Impact of blood loss on lipid peroxidation and on the antioxidative system in victims with isolated injury to the chest and abdomen].

The paper deals with the impact of the volume of blood loss on the time course of changes in the parameters of lipid peroxidation (LPO) and the antioxidative system (AOS) in the sera of 22 and 31 victims with isolated chest and abdominal injuries, respectively, on days 1, 3, 7, and 14 days after injury. All the victims were found to have enhanced LPO processes and altered AOS. The severity of disorders in the LPO-AOS system depends on the size of blood loss, the disorders manifest themselves to a greater extent with over 2-liter brisk bleeding and enhance on days 7 and 14 after injury. In mild blood loss equal to as low as 1.0 liters, there was a mobilization of AOS components, such as (-tocopherol and ceruloplasmin, to the blood bed in the victims with both isolated chest and abdominal injury. AOS failure remaining during all periods of the study was detected in victims with abdominal organs and over 2-liter blood loss. Disorders in the LPO-AOS system were pronounced in abdominal injury. Multimodality treatment in victims with isolated injury of the chest and abdomen does not normalize impaired LPO processes and AOS, which makes it necessary to include into antioxidative therapy for brisk bleeding.

Abdominal Injuries↗

[Ultrasound methods of examination in the determination of therapeutic strategy in patients with spleen injuries].

Based on experience of ultrasonic diagnosis of spleen damages in 86 patients it was established that specificity of the method is 99%, accuracy--97%, sensitivity--83%. Dynamic ultrasonic examinations identify to the group of patients with severe combined trauma and spleen damage who may be treated conservatively. This group consists of patients with small quantity of free fluid in left subdiaphragmatic space and stable changes in splenic parenchyma. Increase of hematoma, presence of blood flow in it, increase of spleen sizes are the indications for surgical treatment.

Hematoma↗

[Diagnosis and treatment of diaphragm ruptures].

72 cases of diaphragm's ruptures in patients with serious combined trauma illustrated basic methods of diagnosis in this condition including X-ray, ultrasonic methods, computed tomography and thoracoscopy. In 26.3% of the patients the diagnosis was made during laparotomy or thoracotomy for massive bleeding because of injury of other organs. In the absence of bleeding the diagnosis was based on signs of the abdominal organs dislocation into the pleural cavity. The differential diagnosis between right-sided coagulated hemothorax and diaphragm's right cupula ruptures was the most difficult.

Abdominal Injuries↗

[Surgical tactics in closed injuries of the liver].

The results of treatment of 116 patients with closed liver injuries are available. 6 types of liver injuries have been determined, depending on location, rupture and safety of certain intraliver structures. To evaluate the rate of seriousness of a liver injury and decrease the rate of blood loss methods of a temporary haemostasis were used; after that the location and depth of the ruptures were estimated; safety of the vessels, bile tracts and liver parenchyma was evaluated. Nonviable parts of the parenchyma were resected. Various methods of haemostasis were used: ligating, laser and plasma coagulation, use of synthetic films. The external liver compression with an elastic splint was used in case of ineffectiveness of the methods mentioned above. The ligating of the hepatic artery should be used in case of the afferent liver vessels injury.

Adult↗

[The surgical treatment of retroperitoneal phlegmons].

Based on the experience with treatment of 112 patients with retroperitoneal phlegmons of different etiology the authors distinguish and describe the diffuse and complicated forms of the disease. In treatment of phlegmons special importance is attached to the optimal surgical access. The article describes main principles of performing sanitation of the suppurative foci of the retroperitoneal space, variants of the aspiration-irrigation methods of treatment of the suppurative process. The authors believe that their original differentiated surgical method using different variants of the aspiration-irrigation drainage is effective in treatment of patients with retroperitoneal phlegmons. This method of treatment gave 23.2% lethality while after the traditional methods of treatment 90% of the patients died.

Cellulitis↗

[Diaphragmatic ruptures in combined injuries to the chest and abdomen].

An experience with diagnosing and surgical treatment of 16 patients with rupture of the diaphragms is described. Operations were performed on 13 patients, 10 of them by the laparotomy access, 3 patients by the transpleural access. In patients with an extensive rupture of the diaphragm continuous respiratory insufficiency was observed in the postoperative period which required the artificial ventilation of the lungs. Eight patients died, 3 of them without an operative treatment, 3--from pulmonary complications and 2--from a cerebro-cranial trauma.

Abdominal Injuries↗

[Injuries of blood vessels of the liver during hepatic trauma].

Radio-angiograms of 33 severe hepatic trauma casualties were analysed. Five types of injury to the liver were identified according to the anatomical disorders of the organ and their localization: 1) complete rupture of the organ; 2) central ruptures with extension of deep fissures from the caval porta along the hepatic vein and formation of intraparenchymal cavities; 3) multiple moderate and small ruptures of both hepatic lobes; 4) ruptures of the peripheral part of the liver; 5) subcapsular and intrahepatic hematomas, contusion of the liver. Injury to vessels of the first-second order were encountered in complete ruptures of the organ, in all other cases intactness of the vascular system was disturbed at the parenchymatous interlobular level.

Adolescent↗

[Characteristics of the diagnosis and surgical treatment of injuries of the duodenum].

Specific features of diagnostics and surgical treatment of injuries of the duodenum in 41 patients with open and closed traumas of the abdomen are described. A wide access by means of mobilization of the right colic flexure should be used for the revision of the duodenum. In cases with closed injuries of the duodenum, in addition to maintenance of its reliable decompression, it is necessary to exclude the intestine from the passage of the gastric content. In order to prevent postoperative pancreatitis cholecystostoma should be made.

Duodenum↗

[The role of microcirculatory disorders in the development of postoperative complications in thoracic and abdominal injuries].

Alterations in the system of microcirculation were found in the postoperative period in 30 patients with trauma of the chest and abdomen which depended upon the blood loss volume and are of plastic character. The main cause of these alterations in the early postoperative period is the change of the microvessels tone. In remote terms of the postoperative period changes of blood rheology play the leading role in alterations of microcirculation. The alterations of microcirculation as one of the mechanisms of the development of polyorganic insufficiency in trauma disease need permanent control and therapy, aimed at correction of tonic and vasomotor activity of resistant and capacitance microvessels, rheological components of blood and ratio of globular volume and plasma.

Abdominal Injuries↗

[Rheological properties of the blood in patients with chest and abdominal injuries in the postoperative period].

Examinations made in 30 patients with a trauma of the chest and abdomen have shown the alterations in blood rheology resulting from the trauma and blood loss to be persistent and often to make progress in the postoperative period. In purulent complications there appear secondary alterations of blood rheology which acquire a lingering character. The syndrome of decreased viscosity of blood is a dangerous disturbance of microcirculation since it is due to the activation of blood cell structures against the background of elevated utilization of hemostasis factors and requires a purposeful therapy.

Abdominal Injuries↗

[Effectiveness of drainage and lavage of the abdominal cavity with regard to morphological peritoneal changes in peritonitis].

The efficiency of intraoperative and postoperative lavage of the abdominal cavity in peritonitis is dependent on the degree of inflammatory and microcirculatory changes of the peritoneum. Lavage of the abdominal cavity by small volumes of liquid under conditions of forced evaculation is efficient in patients with mild disorders of the microcirculation and not very effective in patients with a bacterial shock.

Adolescent↗