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Biomedical subjects

E Sada

Publications and source records attributed to E Sada.

71 records · Page 4Linked to original sources
PubMed1983

Central myelin in the shark Scyllium stellare (Elasmobranchii, Selachii).

The central myelin of the phylogenetically ancient shark Scyllium stellare (Elasmobranchii, Selachii) was examined at the electron microscope. The known different chemical compositions of the myelin in higher and lower vertebrates is not associated in the Scyllium with a lack of any basic structural myelin elements, but is probably linked to variations in the myelin compactness and periodicity. Several unusual myelin structures and irregular patterns of unknown origin have been observed. The relationship between myelin-forming cells and the most external layers of myelinated structures suggest the possibility that the cytoplasmic glial wrapping is not the only mechanism responsible for central myelination in this vertebrate.

Animals↗
PubMed1983

[Clinical use of the serum level of immuno-suppressive acidic protein (IAP) in gastroenterological surgery].

Between September, 1981 and August, 1982, the IAP serum levels were measured in 151 patients to evaluate the correlation between these levels and the clinical spectrum. Pre- and postoperative IAP levels were also compared with the hospital course. Abnormally high IAP levels (greater than 450 micrograms/ml) were observed in malignant diseases, especially in patients with cancer of the pancreas, choledochus, gall-bladder, and esophagus. Of 193 patients, 81 revealed abnormal levels; 28 of these (34.6%) died during this study. The average of their survival time was 2.7 months. Nine of 81 patients (11.1%) experienced severe complications, but recovered. On the other hand, 112 patients with normal IAP levels had a relatively good hospital course; 9 (8%) died. None of the 112 patients experienced any complications. These results suggest that the IAP level may be a good tool in predicting clinical features and prognoses.

Aged↗
PubMed1980

Asymmetry of the habenulae in the elasmobranch "Scyllium stellare". I. Light microscopy.

The habenular nuclei of the elasmobranch "Scyllium stellare" have been studied with conventional histological techniques for light microscopy. Their left-right asymmetry has been defined by the observation of serially cut sections. In addition, their cytoarchitectonic organization has been defined quantitatively. In all specimens observed, the left habenula was larger, longer and richer in myelin than the right. However, it appears that the right habenula is subdivided into more subnuclei than the left. We hypothesize that the morphologic asymmetry of the habenulae might reflect a functional specialization of the two sides of the epithalamus.

Animals↗
PubMedDate not supplied

[Pancreatic cystic fibrosis in Mexicans over 15 years of age].

A better knowledge of cystic fibrosis of the pancreas has contributed to raise the detection of cystic fibrosis in adults. We describe nine Mexican patients older than 15 years with cystic fibrosis. Respiratory symptoms were predominant and they were secondary to bronchiectasis. All patients were infected by mucoid Pseudomona aeruginosa and in some cases, the finding of this microorganism in sputum suggested the diagnosis. In Mexican population the cystyc fibrosis of the pancreas can be found in adult patients, and it should be considered in the differential diagnosis of chronic respiratory diseases in adults.

Adolescent↗
PubMedDate not supplied

Evaluation of enzyme linked immunosorbent-assay and western blot for diagnosis of histoplasmosis.

This study evaluates the use of a enzyme linked immunosorbent assay (ELISA) for the diagnosis of histoplasmosis and it compares it with a complement fixation test. The results showed a sensitivity of 86% in this diagnosis of acute pulmonary histoplasmosis and specificity of 91% using anti-human IgG. For antihuman IgM the sensitivity was 66% and the specificity 100%. There was a good correlation between the titer of complement fixation test and the optical density index by ELISA. Neither ELISA or complement fixation were useful for the diagnosis of disseminated histoplasmosis in immunocompromised patients. Using Western blot we identified antibodies against four different histoplasma antigens (91, 83, 70 and 38 kD) in sera from patients with histoplasmosis. These antigens were identified also in patients with disseminated histoplasmosis. We conclude that ELISA is a useful test for the diagnosis of histoplasmosis, and the Western blot could be useful for the diagnosis of disseminated histoplasmosis.

AIDS-Related Opportunistic Infections↗
PubMedDate not supplied

[AIDS and neoplasms in Mexico].

OBJECTIVE: To describe the epidemiological profile of AIDS and malignancies in Mexico. MATERIAL AND METHODS: The study population included a group of AIDS patients seen at four National Institutes of Health and one at a general hospital in Mexico City, from 1983 to 1992. Demographic, clinical and laboratory information was obtained. RESULTS: A total of 202 patients were studied; 199 men and three women. The mean age was of 34.5 years (range 18-67 years). Kaposi's sarcoma was the most frequent malignancy, with 166 cases, followed by non-Hodgkin's lymphoma, with 33 cases. The three women had non-Hodgkin's lymphoma, one of them associated with cervical carcinoma. Rectal cancer was present in three cases. DISCUSSION: The spectrum of AIDS-associated malignancies in Mexico is similar to that described in other populations. The early diagnosis of this complication is necessary, as well as the search for therapeutic actions to prevent severe immunosuppression and the consequent appearance of malignancies.

AIDS-Related Opportunistic Infections↗