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E Sanchotene

Publications and source records attributed to E Sanchotene.

4 recordsLinked to original sources

Significance of ureteral carcinoma in situ in specimens of cystectomy.

In a retrospective review of 242 cystectomy specimens performed for bladder carcinoma, ureteral carcinoma in situ was found in 14 patients (5.7%), unilateral in 12 and bilateral in 2. Pathology of the bladder specimen was pT4 (6 cases), pT3 (3 cases), pT2 (1 case), pT1 (3 cases), and pT0 (1 case). In the cystectomy specimen and in previous biopsies, they all had grade 3 tumor, and 85% had bladder CIS. Two patients were lost during follow-up. Seven patients (58.4%) died of metastatic disease without evidence of upper tract recurrence (UTR). Their average survival was 15.8 months (range 4-60). Five patients (41.6%) are alive after an average follow-up of 33.6 months (range 18-72 months). In one case an UTR appeared 53 months after cystectomy. In patients with ureteral CIS and long-term survival, a careful follow-up is advisable. The incidence of UTR is increased in this subgroup (8% global and 20% of survivors) but mortality is due to progressive bladder disease.

Carcinoma in Situ↗

[Clinical course in patients with BPH operated for acute urine retention].

Between 1980 and 1990, 5,949 cases of Benign Prostate Hyperplasia (BPH) were detected at the Puigvert Foundation. One thousand of them were randomized for analysis, and it was found that in 347 the indication for surgery was acute urine retention (AUR). During the initial visit the symptoms, their duration, creatinine values, correlation between creatinine and: 1) patients over 70 years, 2) relationship to prostate size, 3) distention of the upper urinary tract, 4) vesical lithiasis, 5) urinary infection, 6) complications, and 7) mortality were analyzed. Discussion of results, comparing these to other series and trying to find evolution differences between these patients and those operated by elective surgery. In our series, we only found statistically significant differences when correlating the high values of creatinine with the prostate size and the upper urinary tract distension.

Acute Disease↗

[From shock-waves even to ureterolithotomy: various practical cases].

The Puigvert Urology Centre in Barcelona reports the detailed results of five cases of ureteric stones all treated by first-line shock wave lithotripsy. Only one case obtained a positive result (after 4 sessions). In the other four cases, shock wave therapy had to be completed by ureteroscopy (1 case) or by open surgery (3 cases) to achieve cure.

Adult↗

[Cytogenetic characteristics and of primary culture in multiple renal tumors].

The incidence of multiple tumours in renal cancer ranges between 1 and 30%. In these cases, it becomes very difficult to differentiate between adenoma and carcinoma just by using conventional methods, particularly in borderline cases. We carried out primary cultures and subsequent cytogenetic studies in 2 patients with multiple renal cancer. Clonal numerical changes in the first case were: 3, 7, 16 and 17 trisomies, chromosome loss; and structural changes, del(1) (p34), del(2) (p16, p22). In the second case, clonal numerical changes were 7 trisomy and tetrasomy and loss of the Y chromosome. Both tumours were cytogenetically characterized as papillary renal tumours. The diagnostic approaches are discussed and the prognosis possibilities evaluated, using this method to evaluate them in multiple renal tumours.

Chromosome Aberrations↗