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Biomedical subjects

E Schoofs

Publications and source records attributed to E Schoofs.

At least 19 recordsLinked to original sources

Hyperfunctioning metastatic follicular thyroid carcinoma in Pendred's syndrome.

A 66-year-old woman with Pendred's syndrome underwent a partial thyroidectomy when she was 17 years old. At the age of 52 years, she had a second thyroid operation because of hyperthyroidism due to a toxic multinodular goiter with a mediastinal extension consisting of several separate nodules. Five years later a hyperfunctioning metastatic follicular carcinoma was diagnosed histologically. After treatment with radioactive iodine, the patient was well. To the authors' knowledge, this is the first description of a metastatic follicular thyroid carcinoma in Pendred's syndrome and the first report of hyperthyroidism occurring after malignant degeneration of a dyshormonogenetic goiter.

Adenocarcinoma↗

Fracture of the body of the hamate bone. Case report.

A patient with a fracture of the body of the hamate bone associated with a proximal and dorsal subluxation of the fifth metacarpal is reported. Treatment consisted of closed reduction and Kirschner wire fixation. A short discussion on fractures of the hamate bone is given.

Adult↗

Mediastinal thymic cyst.

A symptomatic anterior mediastinal mass in a 44-year-old woman was found to be a benign thymic cyst. Complete excision was made by anterolateral thoracotomy. Congenital cysts are benign but differentiation from malignant cystic degeneration should be made.

Adult↗

Peliosis hepatis associated with liver and retroperitoneal abscesses.

A 33-year-old woman was admitted because of coma and severe shock. CT-scan of the abdomen showed the presence of multiple liver abscesses associated with a retroperitoneal abscess which were drained percutaneously. A liver biopsy showed diffuse peliosis. After resolution of the abscesses the patient's general condition improved and she could be discharged from hospital. Peliosis hepatis is an uncommon disorder characterized by dilated sinusoids with formation of blood lakes. Many pathogenetic mechanisms and causal agents have been proposed. Liver biopsy is necessary to establish diagnosis. By withdrawing the offending drug or treatment of the underlying disorder, regression may be observed.

Abscess↗

Evaluation of magnesium before and after jejuno-ileal versus gastric bypass surgery for morbid obesity.

Jejuno-ileal bypass surgery for morbid obesity can cause metabolic and electrolyte imbalances. Another case of severe, symptomatic magnesium deficiency after jejuno-ileal bypass surgery is described. This complication was not encountered in a prospective evaluation of the magnesium status after gastric restrictive bypass surgery. Significant (p less than 0.005) body weight decrease was not accompanied by any (serum, erythrocyte or urinary) evidence of magnesium loss for 12 months after surgery.

Adult↗

Malignant fibrous histiocytoma of the pulmonary artery.

A patient is reported whose symptoms and clinical features were interpreted as pulmonary embolism. However, the ultimate diagnosis was malignant fibrous histiocytoma of the pulmonary artery, which was made evident at operation. Although extremely rare in the early medical literature, primary sarcoma of the pulmonary artery has been reported more frequently during the last decade. This patient may provide further insight into the clinical, diagnostic, and therapeutic features of primary sarcomas of the pulmonary artery.

Aged↗

Pseudotumor formation in polytetrafluoroethylene-dialysis fistulae.

We report two patients with formation of pseudotumors along a polytetrafluoroethylene (PTFE) graft used for dialysis access in chronic fistulae. We postulate a relationship with seroma formation, a known complication of PTFE vascular grafts used for dialysis purposes, possibly through lipolysis of the surrounding fat by a protein-rich exudate.

Aged↗

[Primary choledocholithiasis. Apropos of a case, with review of the literature].

A case study of recurrent bile duct stones, with history of six operations on the bile ducts, is mentioned for his documentary value. The authors give current definitions of recurrent bile stones and give some considerations on surgical and non surgical procedures to treat primary bile stones. Finally, they discuss operative bile duct lesions.

Adult↗