Biomedical subjects

E Sepet

Publications and source records attributed to E Sepet.

6 recordsLinked to original sources

PubMed2001

Hyper-IgE syndrome: a case report.

The hyper-IgE syndrome (HIES) is a rare disorder characterized by pruritic dermatitis, recurrent Staphylococcus skin abscesses and extremely elevated levels of IgE in serum. In this report, an eleven-year-old-boy with hyper-IgE syndrome is presented. He had a coarse facial appearance, pruritic dermatitis, recurrent skin abscesses, pulmonary infection, a reduced rate of resorption of the roots of primary teeth and an elevated serum IgE concentration. The colonization of Candida albicans, Kiebsiella pneumoniae, Escherichia coli and Staphylococcus aureus were found as; (1x10(2) CFU), (2.2x10(4) CFU), (2.2x10(4) CFU) and (2.6x10(3) CFU) per ml saliva, respectively. Also the pulp of a deciduous molar was investigated with light and transmission electron microscope (TEM). As conclusion, treatment for this condition is lifelong administration of therapeutic doses of a penicillinase-resistant penicillin, with the addition of other antibiotics or anti-fungal agents as required for specific infections.

Child↗

PubMed2001

The effect of bone marrow transplantation on systemic and oral health in Fanconi's aplastic anemia.

Fanconi's anemia (FA) is an autosomal-recessive disorder characterized by a progressive pancytopenia, diverse congenital abnormalities and increased predisposition to malignancy. Sixteen children with FA, aged between 4 to 16 were divided into two groups according to treatments. Nine children had bone marrow transplantation and seven children were treated with steroid and/or anapolan. The changes in dental caries, caries-associated microflora, salivary status and periodontal health were investigated in children with FA. Data were analyzed by one-way ANOVA. A statistically significant difference was found in hematological findings between children who have received bone marrow transplantation (BMT+) and the others, who have not received (BMT-). There was no significant difference in dental caries experience, salivary flow rate, buffering capacity, mutans streptococci and Lactobacilli levels between the study groups. A statistically significant difference was found in gingival index, plaque index, bleeding on probing, probing depth scores between the patients with FA in BMT(+) and BMT(-) groups (p<.05). In conclusion, besides systemic control, additional preventive measures during their whole life to maintain oral health is necessary in these children.

Adolescent↗

PubMed1998

Acute lymphoblastic leukemia: dental health of children in maintenance therapy.

The dental health of 41 children aged 4-16 years who were in maintenance therapy from acute lymphoblastic leukemia (ALL) was examined in relation to the period of time in maintenance. There was no significant difference in dental experience and salivary flow rate between the control group and patients with leukemia. Performed treatment index (PTI) and required treatment index (RTI) scores reflected that children, who were in maintenance therapy had insufficient dental care and needed more dental treatments. A statistically significant difference in salivary pH was found between the children, who were in maintenance therapy for 12-24 months and less than 12 months and also the control group; but the pH scores of all groups were observed in normal limits.

Adolescent↗

PubMed1997

Surface texture and enamel-restoration interface of glass ionomer restorations.

The aim of this study was to investigate the surface texture and enamel-restoration interface of Class II glass ionomer restorations in primary molars. A traditional (Chemfil II), a cermet (Chelon-Silver) cement and two light cured glass ionomer cements (Vitremer and Dyract) were used to restore the Class II cavities of 20 primary molars. The surface changes and enamel-restoration interface of restorative materials were evaluated by SEM, after a 12 month period. Microcracks and pores in surface were observed in all of the four different glass ionomer materials. Although, there was no marginal gap formation for Chemfil II, Chelon-Silver and Dyract samples, in 2 samples of Vitremer group gap formation was found with an ion-exchange layer. Also, in Dyract samples wear of restorations was considerable.

Cermet Cements↗

PubMed1995

Artificially formed caries-like lesions around Class II glass ionomer restorations in primary molars.

The aim of this study was to investigate the microleakage around Class II glass ionomer restorations in primary molars. Two different glass ionomer cements and one amalgam control were assessed in vitro by acidified gel technique. Assessment of caries-like lesions was performed using polarized light microscopy. The traditional glass ionomer (Chemfil II) with dentin conditioner provided the highest protection against caries attack and the amalgam restorations provided the least.

Cariostatic Agents↗

PubMedDate not supplied

Factitial (self-induced) gingival disease: four case reports.

Bizarre-appearing gingival recessions that do not correspond to any known gingival disease or oral manifestation of any known systemic disease are called factitial (self-induced) gingival disease. Psychological factors are very important in their etiology. Generally, the lesions occur during the time the child is experiencing stress associated with the frustration of his or her dependency needs. Four cases of self-induced gingival recessions involving children aged 4 to 6 years are presented and investigated from the pedodontic, periodontologic, and psychiatric viewpoints.

Child↗