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Biomedical subjects

E Shalev

Publications and source records attributed to E Shalev.

At least 37 records · Page 2Linked to original sources
PubMed1990

[Fetal ovarian cysts].

Neonatal ovarian cysts are not rare. Most are small follicular cysts less than 2 cm in diameter; larger cysts are less common. Such cysts are usually discovered when complications occur or when they are occasionally detected on systematic clinical examination. 2 cases are presented in infants in whom the diagnosis was made antenatally by ultrasonic scan. In both the cysts regressed spontaneously during the neonatal period. The perinatal management of ovarian cysts should be conservative as complications are very rare and hasty surgery is unwarranted.

Adult↗
PubMed1990

[Cordocentesis].

Explore the source record for details and available documents.

Female↗
PubMed1990

[Cordocentesis for prenatal diagnosis].

Cordocentesis for prenatal diagnosis was being performed in the seventies during the process of fetoscopy. Since then the technique has been used as a diagnostic tool for intrauterine infection, hematological and metabolic disorders and metabolic status of the fetus; and for rapid cytogenic analysis. We report our first 207 cordocenteses performed since December 1985. First puncture was successful in half the cases. The procedure resulted in termination of pregnancy in only 0.96% of cases. Though a new technique, cordocentesis is playing a major role in modern perinatology. The possibility of a direct route to fetal blood vessels early in pregnancy would lead to earlier diagnosis and treatment.

Blood Specimen Collection↗
PubMed1990

Transvaginal sonographic measurement of fetal kidneys in the first trimester of pregnancy.

Fetal renal size late in the first trimester of pregnancy was evaluated by transvaginal ultrasonography in 50 patients not at risk for congenital kidney disease and whose pregnancies resulted in a normal outcome. Both kidneys were reliably identified in all patients scanned at 12 weeks, 13 weeks, and 14 weeks, menstrual age. Kidney diameter measurements obtained in this study are presented for reference in evaluating patients in late first trimester whose fetuses are at risk for kidney abnormalities.

Adolescent↗
PubMed1990

Pregnancy and complicated familial Mediterranean fever.

Familial Mediterranean Fever (FMF) is an inherited disease, closely following the pattern of autosomal recessive inheritance. Amyloidosis is the most severe complication of the disease. The prevalence of pregnancy loss in women with FMF is considered to be high. There is no information to support the possibility of increase risk of late pregnancy complications or change in the natural course of the disease. Two cases are presented with complicated FMF. One case with proved amyloidosis and the second patient with ascites. Pregnancy and neonatal outcome were uneventful in both. No further deterioration in the systemic disease occurred.

Adult↗
PubMed1990

Human fetal behavioral state at term.

The present study was designed to test the existence of behavioral states in the fetus at term using simplified techniques. For this purpose simultaneous recording of the fetal heart activity by means of phonocardiotocography and of fetal body movements by means of real-time ultrasound was performed by using a multichannel recorded. The fetal heart activity was analyzed for two parameters: (1) long-term variability and (2) baseline accelerations. The fetal body movements were classified into three types. 880 min of recording time from 50 fetuses at 37-41 weeks of gestation were analyzed. Each segment of 1 and 3 min was classified into four distinct states, according to the combination of the above parameters. The segments that failed to fit into one of these states were labeled as 'no state'. The frequency of each parameter was also independently calculated. The results were statistically analyzed by using a computer. The significance of the difference between the observed frequencies of the various states and their expected frequencies (obtained by the frequencies of the individual parameters) was calculated by the chi 2 test. Behavioral states of a duration of 3 min were observed in 45.6% of the total periods recorded which is significantly higher (p less than 0.001) than the 4.1% expected.

Female↗
PubMed1990

Fetal habituation to sound stimulus in various behavioral states.

The correlation between arousal state and fetal habituation was tested. Four behavioral states were determined according to fetal heart activity and movement pattern in 52 fetuses. Repeated wide low-frequency sound was used as external stimulus. Ceasing of response to 5 consecutive stimuli indicated habituation. The time from response to habituation was defined as habituation time. Although fetuses in a lower arousal state habituate more rapidly, the difference is not statistically significant.

Acoustic Stimulation↗
PubMed1990

Breast stimulation in late pregnancy. Effect on prostaglandin secretion.

The effect of breast stimulation on the prostaglandin secretion was tested in 13 patients at 38-40 weeks of gestation. Uterine contractions following breast stimulation were documented in all cases. There was an increase in prostaglandin metabolite levels 10 min after breast stimulation.

Breast↗
PubMed1990

Aortic valve replacement during pregnancy. A case report and review of the literature.

Aortic stenosis (AS) is an uncommon complication during pregnancy, but when it occurs it results in significant maternal and fetal morbidity and mortality. We present a gravida with severe AS in which aortic valve replacement was performed in the 3rd trimester of her pregnancy. She had severe AS with mild aortic regurgitation and severe congestive heart failure. Fetal heart rate and uterine activity were monitored and recorded during the operation. The pregnancy was carried uneventfully to term and the patient was delivered of a healthy baby. The literature is reviewed and recommendations are made for the management of AS during pregnancy.

Adult↗
PubMed1989

Exophthalmus--prenatal ultrasonic features for diagnosis of Crouzon syndrome.

Prenatal real-time ultrasonographic diagnosis of exophthalmus is presented. Diagnosis was made at the 35th week of gestation in a fetus of a patient affected with Crouzon syndrome (craniofacial dysotosis). Recognition of exophthalmus as a part of Crouzon syndrome and the easy visualization of the eye balls and palpebrae in the third trimester made the diagnosis possible.

Adult↗
PubMed1989

Selective reduction in multiple gestations: pregnancy outcome after transvaginal and transabdominal needle-guided procedures.

Selective fetal reduction was performed in the first trimester of pregnancy in 20 women with multifetal gestations after ovulation induction with human menopausal gonadotropin (hMG). In 10 women (group A) reduction was performed transabdominally, and in 10 women (group B) the transvaginal approach was used. The transvaginal technique achieved penetration of several gestational sacs without withdrawing the needle from the uterus. Fetal termination using either procedure occurred with intrafetal injection of potassium chloride. Six (60%, group A) and eight (80%, group B) patients delivered healthy newborns. One patient (group B) is at 30 weeks' gestation. Four (40%, group A) and one (10%, group B) aborted 1 day to 8 weeks after the procedure (1 septic abortion, each group). Our results suggest that transvaginal fetal reduction offers a better outcome, with minimal complications, to patients referred for selective continuation of pregnancy.

Abdomen↗
PubMed1989

Fetal motorical and heart response to sound stimulus in different behavioral states.

In 32 fetuses from 37 to 41 weeks' gestation, motorical and heart rate response time, as well as the influence of arousal state on that time were tested. Motorical response time was defined as the time from external stimulus to fetal movement. Heart rate response time was defined as the time from stimulus to the increase in baseline of 15 beats/min. Wide low frequent sound was used as external stimulus. No correlation could be found between motoric and heart rate response time (R = 0.26652). Among the various arousal states the lower arousal state had a significantly longer motorical and heart rate response time.

Acoustic Stimulation↗
PubMed1989

Prenatal diagnosis using sonographic guided cordocentesis.

Cordocentesis has been practiced as a diagnostical tool for prenatal diagnosis of intrauterine infections, hematological disorders, metabolic status of the fetus and rapid cytogenetic analysis. The performance of 198 cordocentesis is presented over 3 years of experience. A 21 gauge spinal needle is inserted via the optimal point on the maternal abdomen under real-time ultrasonic guidance into the insertion of the umbilical cord in the placenta. Successful cordocentesis were achieved in 98.5% of the cases. Termination of pregnancy was directly related to the procedure in only 1%. Hematoma surrounding the puncturing site was demonstrated in one case, but without damage to the fetus. In our series the main indication for performing cordocentesis was the need for rapid karyotyping. The use of fetal lymphocytes for chromosomal analysis offers a rapid and a reliable method for routine clinical demands. The availability of a rapid chromosomal analysis offers a considerable advantage in pregnancies of advanced gestational age. In those pregnancies it appears to be most important to have a rapid diagnosis where anatomical structural anomalies are associated with chromosomal malformations in up to 30%. The metabolic status of the fetus is considered in either acute distress or in cases of suspected sub-optimal metabolic hemostasis, where IUGR or oligohydramnios are demonstrated. Cordocentesis, even though is a new technique, turns to play a major role in modern perinatology. The possibility of a direct rout to fetal blood vessels early during the pregnancy bears the tremendous potential of early diagnosis and treatment.

Female↗
PubMed1989

Reliability of sonographic measurement of the fetal foot.

Reliability of sonographic measurement of the fetal foot was tested. Nineteen fetuses of 16 to 40 weeks gestational age were scanned by two physicians in two different planes of measurements. Repeatability of two measurements of each fetus by the same observer and agreement between the two planes was analyzed using the appropriate statistical method. Good agreement in repeated measurements for and between the two planes was found.

Embryonic and Fetal Development↗
PubMed1989

Fetal habituation to repeated sound stimulation.

Habituation is the progressive decrement of response with repeated stimulation. Neonatologists use this phenomenon to assess newborns for various pathological conditions of the CNS. The present study examined the time required for habituation of the startle response in 103 fetuses at various gestational ages (32 to 40 weeks). The external stimulus was produced by a door buzzer (80 to 90 db). Habituation time decreased as gestational age increased. About 85% of the fetuses showed habituation after less than 20 stimuli, and about 95% after less than 30 stimuli. In all cases habituation time never exceeded 50 stimuli.

Acoustic Stimulation↗