Perforation of a peptic ulcer in an hiatus hernia into the left ventricle.
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Aged↗
Biomedical subjects
E Sheffield
Publications and source records attributed to E Sheffield.
Bronchial casts associated with hilar lymphatic and pulmonary lymphoid abnormalities.
A patient who has expectorated bronchial casts for 23 years is reported. The casts contained mucus, fibrin, and lymphocytes, and the resected middle lobe showed dilated lymphatics with thickened walls at the hilum and lymphoid aggregates in the terminal bronchioles.
Adult↗
Vasculitis complicating cystic fibrosis.
Twelve patients with skin vasculitis complicating cystic fibrosis are described. Seven of these were proven histologically and of these two had systemic vascultitis. Staining of vasculitic tissue by the avidin-biotin immunoperoxidase technique using both monoclonal and polyclonal antisera directed against Haemophilus influenzae, staphylococcus aureus and Pseudomonas aeruginosa did not consistently reveal any bacterial antigens in these tissues. In one patient the vasculitis appeared secondary to ranitidine. There was no evidence of autoimmune disease in any of the patients. Antineutrophil cytoplasmic antibodies were detected in the serum of 40 per cent of the patients with vasculitis complicating cystic fibrosis but in none of 61 controls with cystic fibrosis (but without vasculitis) matched for age and sex and with similar bacteriological flora of sputum.
Adult↗
Anomalous origin of single coronary artery in association with pulmonary atresia.
We report a case of pulmonary atresia with intact septum associated with single coronary artery which originated from the pulmonary trunk. The combination of stenotic pulmonary trunk with presence of right ventricular to coronary artery fistulous connections probably impaired myocardial perfusion after birth.
Coronary Vessel Anomalies↗
Relapsing polychondritis and Weber-Christian disease.
A patient with classical relapsing polychondritis in whom abdominal pain was a prominent symptom is described. Histological examination of skin and mesenteric biopsies confirmed the diagnosis of Weber-Christian disease (systemic panniculitis) suggested by clinical features. The prognostic and therapeutic implications of this unusual disease association are discussed.
Adult↗
Primary B cell malignant lymphoma of the trachea.
A case of primary B cell lymphoma of the trachea is reported. It is suggested that it is an example of a tumour of mucosa associated lymphoid tissue, or "maltoma."
B-Lymphocytes↗
Ultrastructural aspects of sporogenesis in the apogamous fern Dryopteris borreri.
The events that accompany sporogenesis in the apogamous fern Dryopteris borreri parallel those seen in sexually reproducing ferns. Organelles dedifferentiate and redifferentiate, and form a discrete band across the equator of dyads; nuclear vacuoles and lipid spherosomes appear during prophase, and the major part of the ribosome population is removed and subsequently replaced during meiosis. Similar events have been found to occur during sporogenesis in mosses, gymnosperms and angiosperms, and therefore characteristic of the meiotic transition from sporophyte to gametophyte, even in the absence of a transition from diplophase to haplophase. The novel aspects of meiosis in D. borreri are largely those connected with the restitution event that precedes meiosis I and serves to maintain the sporophytic chromosome number throughout the life cycle of this fern. Pre-meiotic cells are regularly found to be cleaved by annular wall ingrowths, which traverse the cytoplasm but not the nuclei. The significance of these ingrowths in relation to theories concerning apogamy and plant cell division are discussed.
Endoplasmic Reticulum↗