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Biomedical subjects

E Sherman

Publications and source records attributed to E Sherman.

25 records · Page 2Linked to original sources

Unexplained in-hospital fever following cardiac surgery. Natural history, relationship to postpericardiotomy syndrome, and a prospective study of therapy with indomethacin versus placebo.

In Part I of this study, the in-hospital course of 219 patients who had undergone a cardiac operation is analyzed. Fever (greater than or equal to 37.8 degrees C, rectal) was present after postoperative day 6 in 159 patients (73%) and was of unexplained cause in 118. Fever decay in the population of unexplained fever patients was exponential. All patients with unexplained postoperative fever were afebrile by postoperative day 19. In-hospital pericardial rub and pleuritic chest pain, widening of the mediastinum on chest film, and pleural effusion were not specifically associated with unexplained postoperative fever. In Part II, 67 patients with unexplained postoperative fever were given indomethacin (100 mg per day) or placebo for 7 days by a randomized, double-blind protocol. Indomethacin resulted in a shorter duration of fever (2.4 vs 3.5 days, P is less than 0.01) and in a shorter duration of chest pain, malaise, and myalgias compared to placebo. Sixty-seven percent of the patients in Part I and all of the patients in Part II were contacted 2-8 months following hospital discharge. Five percent had experienced an illness that we considered to be acute pericarditis, but its occurrence was unrelated to whether the patient had had in-hospital unexplained postoperative fever, in-hospital rub or chest pain, or in-hospital administration of indomethacin.

Cardiac Surgical Procedures↗

Epidemiologic, clinical, laboratory, and therapeutic features of an urban outbreak of chancroid in North America.

An epidemic of 135 cases of chancroid occurred in Winnipeg, Manitoba, Canada, from July 1975 to September 1977. Probable contributing factors for development of chancroid lesions included male sex, lack of circumcision, and genital trauma. A previous history of venereal disease, sexual contact with a person from a bar or hotel in the core city area, unemployment, alcoholism, American Indian or Métis (mixed American Indian and Caucasian) race, and unstable domestic relationships were often accessory findings for infected patients. The tracing and treatment of lesion-free contacts of patients with chancroid may have contributed to the restriction of the outbreak to the core city area. Nineteen isolations of Hemophilus ducreyi were made, most by the use of a new selective medium. Treatment with a short course of penicillin antibiotics was ineffective for 10 of 16 patients, whereas an adequate course of sulfonamide or tetracycline antibiotics, combined when necessary with drainage of fluctuant inguinal abscesses, was effective therapy for most patients.

Adolescent↗

Social reconstruction variables and the morale of the aged.

Key variables from the Kuypers and Bengtson social reconstruction model were operationalized to investigate their relationship to selected measures of morale. They were incorporated in a questionnaire that was completed by 229 retired, noninstitutionalized men and women. Social reconstruction variables were found to have stronger correlations with morale measures than were demographic variables such as age and social class. Reconstruction variables were found to have significant relationships with measures of general happiness and self-esteem, but not with Form A of the Life Satisfaction Index. The interactive effect of social reconstruction variables with one another relative to morale was particularly indicative of the potential heuristic value of the model for both theory and practice.

Aged↗

The meaning of cherished personal possessions for the elderly.

An interview survey was conducted with ninety-four elderly persons, sixty-two in community senior service centers and thirty-two in a nursing home, to find out whether aged persons do identify certain possessions as cherished above all others and to see what meaning these possessions had for their later years. It was found that 81 per cent of the sample could quite readily identify a most cherished object. Different kinds of possessions tended to have different meanings and referents in the lives of the subjects. The lack of a cherished possession was associated with lower life satisfaction scores, which suggests that such a lack might be an indicator of poor adjustment to old age.

Adaptation, Psychological↗