PubMed Health⌕ Search

Biomedical subjects

E Shuttleworth

Publications and source records attributed to E Shuttleworth.

18 recordsLinked to original sources

The launch of MCBEND 10.

MCBEND 10 is the latest release of the general radiation transport Monte Carlo code from the ANSWERS Software Service of Serco Assurance. MCBEND is developed within a Nuclear Code Development (NCD) partnership between Serco Assurance and BNFL. The ANSWERS vision is 'to provide easy-to-use software that meets the current and emerging needs of the user community'. In the case of MCBEND, this vision focuses on the key areas of accuracy, understanding of uncertainties, efficiency and user-friendliness. MCBEND 10 is a major launch of the code with many new and enhanced features. New developments in MCBEND 10 include automatic splitting mesh generation, point energy adjoint for neutrons, calculation of uncertainty in the results due to material cross section uncertainties and a unified source facility. Enhanced features include improved temperature treatment, extended scoring of sensitivity to geometry perturbations, geometry improvements, extensions to formulae and improved user guide image. The user-friendliness of the MCBEND code has been further enhanced by recent developments to the visualisation tools, VISAGE and VISTA-RAY. Developments have been made to the three-dimensional visualisation tool, VISTA-RAY, to simplify the detailed checking of a model, with the option to use a mouse-pointer to select regions of interest for further detail and to visually highlight incorrectly defined areas. A further development to VISTA-RAY is the inclusion of the capability to overlay a representation of a user-designated set of results from a MCBEND analysis on the model. Improvements have also been made to the graphical user interface LaunchPad for submitting and controlling calculation submission, with a common user-image across all the systems. Recent enhancements to LaunchPad include a job-scheduler to simplify processing multiple tasks. A selection of the new developments in MCBEND 10, VISTA-RAY and LaunchPad will be described in this paper.

Algorithms↗

A smoking reduction and cessation program with registered nurses: findings and implications for community health nursing.

A smoking reduction and cessation program was implemented with registered nurses in 3 Canadian provinces. Nurses (n = 117) participated in either an 8-week group or self-directed program using a resource specifically designed for nurses. Questionnaires were administered prior to and at the end of the 8-week interventions and at 6 and 12 months postintervention. Statistically significant changes at 8 weeks in nurses' smoking practices were found on the number of nurses continuing to smoke, mean number of cigarettes smoked, and movement in the stage of behavioral change. Attrition and variation in patterns of quitting over the 12-month study period made assessing participants' longer term outcomes difficult. This study highlights the complexity of assisting nurses to quit smoking and of implementing and evaluating a program based on accepted community health models of practice.

Adult↗

Bilateral gaze paralysis with positive computerized tomography findings. A clinicoanatomic correlation.

The subacute development of an almost isolated bilateral gaze paralysis in a patient with mycosis fungoides allowed a unique opportunity for in vivo clinicoanatomical correlation when enhanced computerized tomography (CT) scan revealed two extremely small lesions of the pontine tegmentum. The larger lesion involved the region occupied by the medial longitudinal fasciculus and the paramedian pontine reticular formation (PPRF) bilaterally, and was alone sufficient to account for the eye movement disorder.

Brain Neoplasms↗

CSF beta-glucuronidase assay in the diagnosis of neoplastic meningitis.

The clinical value of CSF beta-glucuronidase assay in the differential diagnosis of chronic meningitis had been investigated over the past 20 years. Significant (P < .001), often marked, elevation of the enzyme level was found in the first sample submitted in 29 of 30 cases of neoplastic meningitis, irrespective of treatment (mean, 324 units), and in 12 of 14 untreated cases with meningeal lymphoma (mean, 174 units). On the other hand, untreated patients with chronic meningitis of other etiologies had significantly lower of other etiologies had significantly lower levels of enzyme elevation, eg, leukemic meningitis (mean, 46 units), fungal meningitis (mean, 41 units), and tuberculous meningitis (mean, 79 units). In the few cases of chronic meningitis studied during appropriate therapy, a tendency toward a decrease in enzyme activity was noted, thus offering further diagnostic support. In our opinion, the finding of a marked elevation of beta-glucuronidase activity in a patient with chronic meningitis is presumptive evidence of neoplastic etiology.

Diagnosis, Differential↗

Light relief.

Explore the source record for details and available documents.

Aged↗