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Biomedical subjects

E Sitbon

Publications and source records attributed to E Sitbon.

15 recordsLinked to original sources

[Manufacturing of mammary implants: a manufacturing of high technology].

The manufacturing of mammary implants is studied at each step: origin of the silicon, manufacturing of the shells, silicon gels and saline implants. All the process of this manufacturing is now normalised with a tracability that offer today to the surgeon high and homogen quality implants.

Breast↗

Consistency analysis of similarity between multiple alignments: prediction of protein function and fold structure from analysis of local sequence motifs.

A new method to analyze the similarity between multiply aligned protein motifs (blocks) was developed. It identifies sets of consistently aligned blocks. These are found to be protein regions of similar function and structure that appear in different contexts. For example, the Rossmann fold ligand-binding region is found similar to TIM barrel and methylase regions, various protein families are predicted to have a TIM-barrel fold and the structural relation between the ClpP protease and crotonase folds is identified from their sequence. Besides identifying local structure features, sequence similarity across short sequence-regions (less than 20 amino acid regions) also predicts structure similarity of whole domains (folds) a few hundred amino acid residues long. Most of these relations could not be identified by other advanced sequence-to-sequence or sequence-to-multiple alignments comparisons. We describe the method (termed CYRCA), present examples of our findings, and discuss their implications.

Adenosine Triphosphatases↗

[The middle third of the face in facial lift: lipopexy of the premalar fatty pad].

UNLABELLED: The technique proposed tries to resolve an irritating problem which has been incompletely and illogically resolved until now: the restoration of the natural relief of the middle third of the face. An anatomical study shows that the malar region is an eminence composed of a double structure, bony and fatty. The ptosis of what the authors propose to call "the premalar fatty pad" is probably the earliest sign of ageing in the face. It give a skeletal appearance and fills the canine fossa which become a heavy fold and increases the apparent depth of the naso genio labial sulcus. The aim of this technique is to restore a normal appearance by restoration of the true anatomical structures. The technique consists of extensive undermining behind the ptotic fatty pad, in front of the malar bone and SMAS as fas as the orbital rim which allow displacement upwards and backwards. Resorbable sutures and an accurate skin tension ensure the new premalar position of the fatty pad. Posterior fibrosis, in the undermining, will be the essential means of late fixation. 70 such operations with sufficient follow up have been carried out. The result is stable in 58 of them and insufficient but appreciable in all of the others. Fatty faces give poor results due to the poor quality of the skin. CONCLUSIONS: it is a simple, logical and efficient procedure, more often performed in association with the treatment of frontal and cervicofacial level of the face. No complications related to this procedure have been observed.

Adipose Tissue↗