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Biomedical subjects

E Skog

Publications and source records attributed to E Skog.

At least 19 recordsLinked to original sources
PubMed1991

The incidence of basal cell carcinoma in an area of Stockholm County during the period 1971-1980.

A study was made of the incidence of basal cell cancer among a population of residents within a limited catchment area in Stockholm during the period 1971-1980. The age-standardized incidence of basal cell cancer increased by an average of 11.9% per year (p less than 0.005) and the incidence rate more than doubled during the ten-year period. There was no statistically significant difference in the rate of increase for men and women. Nor was any such difference noted between face, head and neck and other skin areas.

Adolescent↗
PubMed1986

The histopathogenesis of the flame figure in Wells' syndrome based on five cases.

Characteristics of Wells' syndrome are recurrent episodes of edema and erythema of sudden onset, often covering large areas of the skin. Microscopy shows marked eosinophilia and the presence of so-called flame figures. The flame figures have been considered to be either secondary to aggregates of expelled eosinophilic granules and disintergrating eosinophils, or foci of necrobiotic collagen. Our study indicates that the flame figure is secondary to disintegration of eosinophils and consists of aggregates of eosinophilic granules and nuclear fragments and not of necrobiotic collagen. We consider Wells' syndrome to be a distinctive clinical and histological reaction, which can be triggered by many different, mostly unknown factors.

Adolescent↗
PubMed1983

A randomized trial comparing cadexomer iodine and standard treatment in the out-patient management of chronic venous ulcers.

Ninety-three patients with treatment-resistant venous ulcers were included in a multicentre randomized trial to compare cadexomer iodine and the standard treatment used in each centre combined with compression bandages, in healing venous ulcers. The mean duration of ulcers before the trial was more than 2 years. With standard treatment the mean ulcer size increased slightly during the 6-week trial whereas with cadexomer iodine the ulcer size was significantly reduced. Cadexomer iodine was more effective than standard treatment for reduction of pain, removal of pus and debris, removal of exudate, stimulation of granulation and reduction of surrounding erythema. Bacterial infection of ulcers increased or did not change during treatment with the standard therapy whereas cadexomer iodine significantly reduced infection with Staphylococcus aureus, Pseudomonas aeruginosa and other pathogenic organisms. A correlation was seen between the time taken to reduce or eliminate infection with Staphylococcus aureus and rate of ulcer healing. Four patients complained of transient pain in the ulcer after application of the cadexomer iodine. It is concluded that cadexomer iodine increased the rate of healing of infected chronic venous ulcers.

Administration, Topical↗
PubMed1983

Atopic hand dermatitis: a comparison with atopic dermatitis without hand involvement, especially with respect to influence of work and development of contact sensitization.

A group of 77 patients with atopic hand eczema were compared with 136 atopic dermatitis patients without hand manifestations. Age distribution was identical in the two groups, peaking at 25-39 years of age. Both groups were dominated by female patients. No differences existed between them with respect to atopic heredity, occurrence of other atopic manifestations, or distribution of serum IgE values. The fingers represented the predilection sites for hand involvement. Patients with hand lesions changed jobs more frequently (p less than 0.001) than those with unaffected hands, and change from a wet or unclean occupation was more common (p less than 0.001) than from a dry one. Change of work entailed improvement in the skin status of both groups. Prevalence of positive patch test reactions was high and statistically identical in both groups. Occurrence of positive responses did not explain the development of hand affliction; in only 3 patients did the test result correspond to exacerbation of the hand eczema. The number of positive reactions was high in patients with low serum IgE levels, while high levels were associated with fewer positive patch test reactions.

Adult↗
PubMed1980

Incidence of cosmetic dermatitis.

During 1973-1978, 41 cases of contact dermatitis due to cosmetics were recorded at a skin clinic in Stockholm serving a catchment population of about 250,000 people. Most of the cases were of allergic contact dermatitis and due to eye make-up and antiperspirants.

Adolescent↗
PubMed1978

Comparison between 24- and 48-hour exposure time in patch testing.

A pilot study was performed to compare the results obtained by leaving the test substances recommended by ICDRG on the backs of the patients for 24 and 48 h, respectively. The Pirilä chamber test method was used. We got different results between the two methods of application time as reported, and intend to continue the study.

Humans↗
PubMed1977

Immediate reactions to patch tests with balsam of Peru.

Closed patch tests with balsam of Peru gave rise to nine immediate reactions among 121 patients with different dermatoses and to 10 reactions among 57 patients with chronic urticaria. Among compounds of balsam of Peru, cinnamic aldehyde, cinnamic acid benzoic acid and benzaldehyde also gave the same reactions. The reactions could not passively be transferred with serum from patients. They were abolished by antihistamine given before testing, and by pretreatment with compound 48/80. Balsam of Peru and cinnamic aldehyde did not provoke new symptoms when given orally to patients.

Balsams↗
PubMed1976

Patch testing, tuberculin testing and sensitization with dinitrochlorobenzene and nitrosodimethylanilini of patients with atopic dermatitis.

Cell-mediated immunity was studied in patients with atopic dermatitis. 113 patients were patch tested with ten contact allergens. The frequency of positive reactions to patch testing with "common contact allergens" was found to be lower in patients with "high IgE values" than in those with IgE less than or equal to 1000 U/ml. A larger number of patients with severe dermatitis reacted negatively to PPD and were more difficult to sensitize with DNCB and NDMA as compared with the patients with mild dermatitis. The results of this investigation support the findings of earlier workers that patients with atopic dermatitis show disturbances in the cell-mediated immune system and these disturbances appear to be correlated to the degree of severity of the dermatitis.

Adolescent↗