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Biomedical subjects

E Softova

Publications and source records attributed to E Softova.

7 recordsLinked to original sources
PubMed1994

[The functional and morphological changes in the liver and kidneys of white rats treated with aluminum].

A total of 126 white male Wistar rats under subacute conditions were studied. Of them, 76 were perorally treated with AlCl3 in a dose of 3 mg/kg b.w. daily for 40 days. Activities of acid phosphatase (AP), succinate dehydrogenase (SDH), adenosine triphosphatase (ATP-ase) and the contents of glycogen, glucoproteins and RNA were dynamically followed-up in the liver and kidney. Serum activities of ASAT and ALAT were estimated by Borhringer's tests. Morphological changes were histochemically investigated. There was an initial elevation followed by reduction mostly manifested for SDH and ATP-ase and an increase of AP at the end of trial. Histochemical data argued for disorders of protein and carbohydrate metabolism. Morphological alterations more outlined in the liver became more severe until the end of the experiment.

Administration, Oral↗
PubMed1981

[Biochemical and histochemical studies of the alkaline phosphatase and adenosine triphosphatase levels in the lymph nodes of experimental animals after noise exposure].

The authors examined biochemically and histochemically the activity of alkaline phosphatase and adenosinetriphosphatase in lymph nodules of experimental animals, living under the conditions of continuous noise action (3 and 5 months) at a level of 95 decibels A for 3 hours daily in the morning. There were phase changes in the activity of the examined enzymes, which revealed considerable stability even after stopping the contact of the organism with noise factor. The manifested inhibition of the activity of alkaline phosphatase and partly of adenosinetriphosphatase suggested that the cells of lymph tissue revealed disturbances in the metabolic processes, which caused exhaustion of their protective function.

Adenosine Triphosphatases↗
PubMed1977

[Acromegalic cardiopathy].

A patient with acromegaly is described with a relatively small eosinophilic adenoma of the hypophysis, the cardiopathy standing out on the foreground of the clinical pictrire, due to which it has for a long time been interpreted as a primary cardiac ailment. The cardiac disorder proceeds with cardiomegaly, conductivity disturbances and left, quickly progressing into complete and resistant to treatment cardiac insufficiency. The problem of the origination of the so called primary cardiac insufficiency is discussed, resulting from the direct effect of STH upon myocardium.

Acromegaly↗