Solid phase synthesis of oligoribonucleotides.
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Biomedical subjects
Publications and source records attributed to E Stankevich.
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Five newly synthesized hydrazides: L-aspartic acid dihydrazide, DL-ureido-succinic acid dihydrazide, DL-dihydroorotic acid hydrazide, orotic acid hydrazide, and 2,2'-anhydro-1-(beta-D-arabinofuranosyl)-orotic acid hydrazide were tested for mutagenicity in the Ames test. All these hydrazides except DL-ureidosuccinic acid dihydrazide were found to be non-mutagenic. The mutagenic activities of the latter compound which causes base-pair substitution was decreased in the presence of metabolic activator.
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