PubMed Health⌕ Search

Biomedical subjects

E Stankevich

Publications and source records attributed to E Stankevich.

6 recordsLinked to original sources

Mutagenicity of hydrazides of pyrimidine-nucleotide-precursors in the Salmonella-oxygenase test.

Five newly synthesized hydrazides: L-aspartic acid dihydrazide, DL-ureido-succinic acid dihydrazide, DL-dihydroorotic acid hydrazide, orotic acid hydrazide, and 2,2'-anhydro-1-(beta-D-arabinofuranosyl)-orotic acid hydrazide were tested for mutagenicity in the Ames test. All these hydrazides except DL-ureidosuccinic acid dihydrazide were found to be non-mutagenic. The mutagenic activities of the latter compound which causes base-pair substitution was decreased in the presence of metabolic activator.

Animals↗