Biomedical subjects

E Stepanian

Publications and source records attributed to E Stepanian.

3 recordsLinked to original sources

PubMed1992

[Strabismus induced by peripheral vestibular lesions].

Little attention has been paid in the ophthalmological literature to strabismus resulting from lesions located in the peripheral vestibular system. However, this phenomenon is commonly encountered in clinical practice. As a rule, this kind of strabismus shows a prominent vertical component. It is generally combined with a change in perception of verticality, conjugate cyclotorsion of the eyes, and head tilt. This association is known as "ocular tilt reaction". It occurs in a number of clinical settings which are believed to be related with alteration in the otolithical and/or vertical semicircular canal pathways. Strabismus occurring as a feature of ocular tilt reaction might result from different mechanisms according to the location of the lesion, e.g. in the utricles, in the midbrain tegmentum, and in the dorso-lateral medulla oblongata. This phenomenon is illustrated here with the report of a patient suffering from Ménière disease, who underwent selective vestibular neurectomy. Methods of ophthalmological evaluation in such cases is described.

Aged↗

PubMed1992

[Phacoemulsification: technical initiation at what price?].

Phacoemulsification of the cataract is perhaps technically superior which is considered "classic". This technic consists however of a number of difficulties that may be mastered during an apprentiship. Considerable complications may arise during this initiation periods; imposing this surgical method on patients is thus an ethical problem. If the risks encountered during the apprentiship of phacoemulsification appear comparable to those during the classic extracapsular technique, phacoemulsification may be recommended with less reservation. We have compared 250 initial cases of classic extracapsular extraction with 250 "initial cases" of phacoemulsification, taking into account operative and post-operative complications and final functional results.

Adult↗

PubMed1991

[Immunolocalization of fodrin in the retina of vertebrates].

Fodrin, a member of the spectrin family, is abundantly found in brain and lens. Based on its often observed peripheral cellular distribution, it is generally believed that fodrin - like other spectrins - participates in the linkage of membrane components to cytoskeletal elements providing their anchorage to distinct, highly specialized membrane regions. To investigate the role of fodrin in the vertebrate (amphibian) retina, we have produced polyclonal antibodies in rabbits against fodrin purified from veal lens. The distribution of fodrin within the retina of Xenopus and Rana has been assessed by indirect immunofluorescence on cryostat sections and on isolated epithelial cells. In general, the staining pattern reflects the structural and functional polarity of the retinal layers. Fodrin is found in axons, dendrites and synapses of neurons, in the inner segment of photoreceptors, and as a peripheral ring of the epithelial cells. This study represents the first step of an investigation on the development and differentiation of specific, fodrin-containing membrane regions in the amphibian retina.

Animals↗