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Biomedical subjects

E Stephan

Publications and source records attributed to E Stephan.

At least 37 records · Page 2Linked to original sources
PubMed1987

[Use of process and turning point in psychotherapy--significance of the theatrical aspect as a cooperative mode of behavior].

The paper presents observations respecting the contrast of playful and grim attitudes in the behavior of patients undergoing psychotherapeutic treatment. Playful correspondence to Erikson's Cooperative Stage of development and Freud's mature Genitality, while grim corresponds to Erikson's Autonomous and Assertive Stages and Freud's Anal and Phallic Stages. To be effective, theatrical performances have to be produced in a cooperative way; psychotherapy too must assist the patient to achieve a greater degree of cooperativeness and mature Genitality. Identifying with the therapist and adapting his style can enable the patient to acquire self-composure through playful behavior, and to overcome protracted grimnes. Play-matured Genitality Cooperative signifies that the patient incorporates his partner or opponent's intentions into his appreciation of events, enabling him to act more in accordance with the reality around him.

Adaptation, Psychological↗
PubMed1981

Further experience with the two-stage anatomic correction of simple transposition of the great arteries.

Between May 1976 and January 1981 a two-stage anatomic correction was performed in 25 patients with simple transposition of the great arteries, ranging in age from 41/2 to 46 1/2 months (mean 14.8). A first-stage operation, consisting of banding of the pulmonary artery to redevelop the left ventricle, including a Blalock-Taussig-anastomosis in 4 patients was performed prior to anatomic correction. Of 33 patients, who underwent first-stage correction there were 3 early deaths (9%). The interval between the first and second stages was 5 weeks to 9 months (mean 4.3 months). After the first-stage operation, the peak systolic left ventricular pressure rose from 34 +/- 11 mmHg to 80 +/- 16 mmHg with no significant change in enddiastolic pressure. After anatomic correction there were 5 early deaths (20%) of whom 4 were due to left heart failure. There was no correlation between death and the age of the patients at the time of anatomic correction. By our current criteria the ventricles were not adequately prepared for correction in these four patients. The coronary arteries, with different types of origin, could be reimplanted to the posterior vessels without kinking, tension or torsion in all cases. After correction, the ECG and vectorcardiogram rapidly changed toward normal. The arterial oxygen saturation was higher than 95% in all patients. Recatheterization performed in 11 patients, 3 weeks to 27 months after correction, showed normal left ventricular pressure at rest in all children, except in 2 recatheterized early after correction, who had moderately elevated left ventricular enddiastolic pressure. Right ventricular peak systolic pressure decreased to normal limits. The aortic and coronary anastomoses showed normal growth in cineangiography. Although the two-stage corrections of simple TGA may have its own problems, investigation suggests that results are encouraging.

Child, Preschool↗
PubMed1979

[The combination mass radiography--blood pressure measurement. Experiences and results in the Canton Bern].

The combination of mass radiophotography and blood pressure measurement was started in the Canton Berne (population approx. 1 million) in 1974. Experience with this method has been highly satisfactory: An average of 80% of personnel attented mass radiophotography on a voluntary basis and 97--i00% participated in the blood pressure measurement. The costs were low because a well-established service could be utilized. In this way, it has been possible to examine 90,000 persons within three years, or 45% of the population (age 30 to 65 years). The results for 1977 were analyzed using a general computer program. A total of 17,112 persons aged 30 years and more and belonging to the working population were examined: 14.6% of the screened population had hypertension of greater than or equal to 160 and/or greater than or equal to 95 mm Hg. Diastolic pressure was found to be greater than or equal to 100 mm Hg in 5.9% and greater than or equal to 110 mm Hg in 1.8%. 54.8% of the detected hypertensions were unknown to the examined persons and 17.8% were under treatment. Correlations with other findings, such as pathologic images of the heart in the X-ray and smoking, have been investigated. An interesting fact was the remarkable difference in the percentage of hypertension between population groups (10.7--20.7%) and occupations such as industry, trades and public utilities (3.0--29.8%). It has been shown that screening for hypertension is not only a propaganda move. A large number of undetected hypertensive subjects can be passed on for treatment.

Adult↗
PubMed1979

[Reconstruction of the right ventricular outflow tract in tetralogy of Fallot with a Hancock valve containing ventriculo-pulmonary conduit (author's transl)].

Between June 1975 and August 1978, 22 cases of anatomically and functionally severe tetralogy of Fallot were corrected with a valve bearing ventriculo-pulmonary Hancock conduit. The indication for use of the Hancock conduit was atresia of the pulmonary valve ring and main pulmonary artery (classified according to Sommerville and Jefferson as types I and II respectively) in 5 patients, severe hypoplasia of the pulmonary valve ring, the right ventricular outflow tract (RVOT) and the main pulmonary artery in 10, 1 patient with an abnormal right coronary artery and an acquired obstruction of the infundibulum subsequent to Waterston-Cooley anastomosis in 4 patients. Hancock conduits (KHP) were also employed in two patients with severe pulmonary insufficiency after patch insertion across the pulmonary valve ring. Early mortality was 9%. Very good hemodynamic results were achieved in 15 patients (with pRV/pLV ratios less than 0.4 in 8 and between 0.4 and 0.5 in 5 patients). Good results (as indicated by pRV/pLV ratios between 0.5 and 0.7) were found in 7 patients, while only in 2 patients a ratio greater than 0.7 indicated an insufficient hemodynamic result. The valve bearing ventriculo-pulmonary Hancock conduit is the surgical method of choice for various types of atresia of the RVOT. As opposed to transanular reconstruction of the RVOT which, dependent on the extent of hypoplasia, consistently leads to some degree of pulmonary insufficiency, the use of the Hancock conduit can prevent pulmonary regurgitation.

Heart Valve Prosthesis↗
PubMed1978

Purification of placental alpha-1-foetoprotein.

Quantitation of placental alpha-1-foetoprotein was done by the radioimmunoassay technique and gave a mean value of 6060 +/- 22.2 ng/g fresh tissue. The purification process included three methods. (1) Protein precipitation was performed using ammonium sulphate at 50 and 70% saturation. Elution on a Concanavalin A-sepharose column was used to diminish the interference of albumin with alpha-foetoprotein. (2) A coupling immunoadsorption technique using CNBr-activated Sepharose 4-B, antialbumin and antitransferrin, was found to be more reproducible. (3) Counter-immunoelectrophoresis and discontinuous gel electrophoresis gave a 60% yield with a 400-fold purification.

Chromatography, Affinity↗
PubMed1978

[Radiography services: old and new tasks].

At the beginning of mass-radiophotography campaign the main interest was the fight against tuberculosis. Today the point of view has completely changed. The detection of all the diseases of the chest, the evaluation of risk groups and the combination with other screenings such as blood pressure measurement have largely improved the efficiency of the campaigns.

Animals↗
PubMed1977

Variation in serum immunoglobulin levels in acute trichinosis.

An early rise in serum IgE levels was observed in five of seven patients with acute primary trichinosis. Parallel increases in the total IgG, IgM, and Iga levels, as well as specific IgG and IgM antibody titres to Trichinella spiralis larval antigen, were detected in two. The elevated levels persisted long after the clinical recovery of the patients.

Female↗
PubMed1975

Serodiagnosis by fluorescent antibody staining of an outbreak of trichinosis in Lebanon.

The opportunity offered by a recent outbreak of trichinosis in Lebannon was utilized to evaluate the applicability of an indirect fluorescent antibody (IFA) test for early diagnosis. Freeze-dried T. spiralis sonicated larval antigen fragments were used, together with human test serum and monospecific anti-human IgG, IgM and IgA fluorescein conjugates. Diagnostic IgG levels of 1/100 and above were observed in serum obtained some time during the acute phase of illness from nine out of ten patients. Diagnosis was made in seven cases within 30 days after the onset of symptoms. IgM antibodies were demonstrated in occasional samples. No IgA antibodies were detected. IgG levels of 1/100 were present in only four out of ten samples obtained 150 days after the clinical onset. These observations suggest that freeze-dried larval antigens make the IFA test an easy and useful procedure in the diagnosis of acute trichinosis. In chronic cases the efficacy of the method appears to be poor.

Acute Disease↗