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Biomedical subjects

E Suarez

Publications and source records attributed to E Suarez.

51 records · Page 3Linked to original sources
PubMed1983

Treatment of liver hydatid disease with mebendazole: a prospective study of thirteen cases.

We have prospectively studied the evolution of 13 patients with liver hydatid cysts treated with mebendazole. Two patients also had peritoneal hydatid disease in addition to liver cysts. One of the two also had a retrovesical cyst. Liver cysts disappeared in three patients. In one, the liver cyst reappeared and in another a new cyst was observed after treatment was stopped. Therapy was most effective in young patients, in small cysts, in one case of peritoneal hydatid disease and in one case of a retrovesical cyst. Side effects warranted interruption of therapy in three cases, although we cannot be sure that they were due to mebendazole treatment. We recommend long-term patient follow-up once the cyst can no longer be identified by ultrasound.

Adolescent↗
PubMedDate not supplied

Peripheral corneal disorders.

The peripheral cornea is anatomically and physiologically distinct from its central counterpart. The major differences relate to the gradual transition of corneal tissues to those of the conjunctiva, episclera, and sclera; furthermore, the vascular structures, lymphatics, and inflammatory cells from these neighboring structures are intimately associated with the limbus and periphery of the cornea. The peripheral cornea is thereby predisposed to three main classes of disorders which do not normally involve the central cornea. First, local conditions affecting the sclera and conjunctiva may secondarily spread to involve the limbus and peripheral cornea. These include several infectious diseases, as well as hypersensitivity conditions, mass lesions, and degenerations. Second, due to the associated blood vessels and lymphatics, the peripheral cornea may be involved in a variety of systemic diseases, including vasculitides, autoimmune disorders, and abnormal metabolic conditions. Finally, there are several conditions, such as the noninflammatory peripheral degenerations, which primarily affect the peripheral cornea without associated ocular or systemic changes. In this review, we present a classification and discussion of the various disorders which may involve the peripheral cornea.

Aging↗
PubMedDate not supplied

A model for selecting a clinical laboratory information system. A four-phase process.

Laboratory information systems (LISs) have become an essential part of an efficient and effective laboratory. In the past, selecting an LIS was a relatively simple procedure because there were only a few candidates to select from. Now, however, selecting an LIS from the myriad available has become a time-consuming and complex process. This article presents a multi-attribute utility (MAU) method for selecting an LIS. This MAU method has four phases: identifying LIS vendors and disseminating requests for proposals (RFPs), analyzing RFP responses and selecting the top three vendors, validating responses of the top three vendors, and selecting a primary vendor and preparing a formal recommendation. By following this four-phase process, laboratories will simplify the complex LIS selection process and increase their chances of selecting the best LIS for their needs.

Clinical Laboratory Information Systems↗
PubMedDate not supplied

Influence of several surgical techniques in peptic ulcer disease on the oral kinetic of a basic drug.

The effect of gastric surgery on the absorption of a basic drug propranolol was studied in 11 patients. 80 mg of propranolol were administered orally before and after surgery. Irrespective of the surgical technique, there was only a significant decrease in the absorption constant Ka (1.10 +/- 0.14 vs 0.72 +/- 0.09) (p < 0.05), indicating a delay in the gastrointestinal absorption, which agreed with the delay in the urine excretion in the first six hours after surgery (6.8 +/- 0.8 vs 1.7 +/- 0.4) (p < 0.001). Patients with vagotomy but without gastric resection showed a significant increase in the time of attainment of peak concentration tmax (2.4 +/- 0.2 vs 3.2 +/- 0.3), and decrease in Ka (1.5 +/- 0.12 vs 0.73 +/- 0.17) (p < 0.05), indicating also a delay in the gastrointestinal absorption, that is not seen in patients with partial gastric resection. We conclude that vagotomy with gastric resection does not modify the absorption of propranolol, and vagotomy without resection delays its absorption but does not decrease it.

Administration, Oral↗