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E T Bainbridge

Publications and source records attributed to E T Bainbridge.

10 recordsLinked to original sources
PubMed1984

Gastro-oesophageal reflux in pregnancy. Altered function of the barrier to reflux in asymptomatic women during early pregnancy.

The object of this study was to investigate the effect of early pregnancy on the competence of the barrier to gastro-oesophageal reflux (GOR). Oesophageal manometry and prolonged intra-oesophageal pH monitoring were carried out in 12 asymptomatic pregnant women and in 7 non-pregnant women. There was no significant difference in mean intragastric pressure between these two groups. However, both mean lower oesophageal sphincter (LOS) pressure and mean barrier pressure (LOS pressure minus intragastric pressure) were significantly lower in the pregnant subjects (16.9 +/- 0.79 mm Hg; 8.69 +/- 0.73 mm Hg) than in the controls (21.5 +/- 1.93 mm Hg; 14.1 +/- 1.22 mm Hg) (p less than 0.01 and less than 0.001, respectively). No significant difference could be demonstrated between the two groups with regard to degree of GOR, although the pregnant women did exhibit a tendency towards more marked reflux. The results indicate a diminution in the barrier to reflux in early pregnancy due to a reduction in LOS pressure, which may be the basis of symptomatic GOR in pregnancy.

Adult↗
PubMed1983

Some changing aspects of primary hyperparathyroidism.

Ninety eight patients who underwent cervical exploration for primary hyperparathyroidism are reviewed. The detection of this condition in increasing numbers of patients, particularly those with minimal or no symptoms is confirmed. Initial exploration was successful in 92 cases using visual localisation with immediate frozen section examination of any presumed parathyroid tissue. The high incidence of solitary adenomata (84%) and low rate of recurrent hypercalcaemia support a "conservative" surgical approach as opposed to routine sub-total parathyroidectomy. The most common complication of surgery was hypocalcaemia, which is preventable by avoiding routine exhaustive exploration for, and unnecessary biopsy of, normal glands.

Adenoma↗
PubMed1982

Primary hyperparathyroidism due to overactive intrathyroid parathyroid glands: a potential cause of failed exploration.

The variable location of the parathyroid glands is a significant factor in unsuccessful cervical exploration for hyperparathyroidism. Particular difficulty may be experienced when an overactive parathyroid is concealed within the substance of the thyroid. Currently available methods of localizing abnormal parathyroid tissue may well fail to indicate an intrathyroid location. The latter possibility should always be considered whenever thorough cervical exploration has failed to reveal a parathyroid tumour as such awareness may obviate re-exploration or an unnecessary sternotomy. This report details the clinical features and operative findings in 6 patients whose primary hyperparathyroidism was due to an overactive intrathyroid parathyroid gland. Successful parathyroid surgery demands a strict routine exploration of the possible sites of overactive glands, virtually all of which are easily accessible through a standard collar incision.

Adenoma↗
PubMed1980

Hypoxaemia after left thoracotomy for benign oesophageal disease.

Arterial blood gases were measured before and after operation in 14 patients undergoing conservative oesophageal surgery via a left thoracotomy. All the patients had a preoperative partial pressure of oxygen (PO2) of greater than 10 kPa, and none gave a history of chronic respiratory disease. All exhibited a fall in PO2 values after operation, the mean maximum reduction being 31%. The overall pattern of hhypoxaemia was similar to that previously reported after pulmonary resection, and upper abdominal surgery, characterised by the greatest reduction in PO2 on the first two postoperative days, followed by a gradual return towards preoperative values. In addition, there was a marked similarity in the degree of hypoxaemia observed by Parfey et al and by ourselves. These findings are attributed to similar changes occurring in pulmonary function in both series of patients, caused at least in part by different factors associated specifically with the two surgical approaches involved. In our experience, left thoracotomy, even without pulmonary resection, is associated with significant postoperative hypoxaemia. Knowledge of this may assist in the selection of patients for surgery and in their subsequent management.

Adult↗
PubMed1976

Angiomatous lymphoid hamartoma of the pelvis.

A mass removed from the pelvic retroperitoneal tissues of a 24-year-old women was found to be an angiomatous lymphoid hamartoma. The clinical, radiological and histological features are described, and the problems encountered in diagnosis discussed.

Adult↗
PubMedDate not supplied

Inflammatory aneurysms of the abdominal aorta with associated ureteric obstruction or medial deviation.

Six cases of ureteric involvement in the retroperitoneal fibrosis associated with inflammatory aneurysms of the abdominal aorta are described. Though of uncertain aetiology, such aneurysms appear to constitute a distinct disease entity. The treatment of choice of an inflammatory aneurysm with ureteric obstruction is aneurysmectomy and ureterolysis. In unfit patients, ureterolysis alone or the administration of steroids is indicated. Pre-operative diagnosis of aneurysms of the inflammatory type may be possible with the aid of intravenous urography and erythrocyte sedimentation rate determination. The value of ultrasonography and computed tomography in diagnosis is still to be proven. Some modification of the standard technique of aneurysmectomy may be necessary when other retroperitoneal structures have been rendered inseparable from the aortic wall due to their involvement in the dense inflammatory fibrous reaction.

Aged↗