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Biomedical subjects

E T Johnson

Publications and source records attributed to E T Johnson.

6 recordsLinked to original sources

Accidental falls among geriatric patients: can more be prevented?

The potential for accidental falls among geriatric patients is of mounting concern. Two hundred forty-one accidental falls over a 12-month period at the VA Medical Center were analyzed retrospectively and the literature reviewed in order to highlight factors that have bearing on the incidence and severity of falls. If a patient's potential for falling could be identified through a grading system based on these premonitory features, preventive measures might be more clearly focused where needed to reduce this frequent hazard in our hospital population.

Accident Prevention

The condom catheter: urinary tract infection and other complications.

A retrospective study of 64 geriatric patients on an extended care unit at the VA Medical Center strongly suggested that long-term use of a condom catheter drainage system (CCDS) (mean use, 35 months) was regularly associated with urinary tract infection. Common nosocomial pathogens were found, particularly Proteus-Providencia. The CCDS was also associated with significant penile complications. It is hoped that these hazards can be minimized by careful application and monitoring of the CCDS.

Aged

Nosocomial infection: update.

A preceptor program on nosocomial infection is offered at the Tuskegee VA Medical Center every six months. It is the only program of this type offered by any VA hospital. Enrollees include infection-control officers from regional hospitals who attend lectures and demonstrations covering a broad range of related issues. It is now accepted that such preceptorships, by increasing awareness of the risk factors and understanding of available preventive controls, can reduce the incidence of nosocomial infections.Up to 5 percent of the 40 million patients admitted to US hospitals each year are compromised by an infection acquired during the hospital stay. This leads to 70,000 deaths per year. The urinary tract is the origin of 40 percent of all nosocomial infections, and surgical wounds account for another 25 percent. Pneumonia is the culprit in 15 percent of cases. Primary bacteremias make up only 4 percent of nosocomial infections, but the mortality is 30 to 50 percent.Staphylococci and gram-negative bacilli, especially E coli, are the common organisms found in hospital-acquired infections. Opportunistic pathogens such as Pseudomonas, Serratia, Candida, and a host of others, including Legionella, are found in debilitated patients.

Cross Infection

Use of solid-phase extraction systems to improve the sensitivity of Artemia bioassays for trichothecene mycotoxins.

Solid-phase extraction was used to preconcentrate trichothecene mycotoxins from rivers and streams in order to develop and improve a rapid and sensitive bioassay using the brine shrimp Artemia salina. For T-2 toxin, HT-2 toxin, and 4,15-diacetoxyscirpenol, LC50 values obtained were 172, 600, and 700 micrograms/L, respectively. The LC50 for 4-deoxynivalenol was 21 mg/L. A more than 5-fold increase in sensitivity was observed when solid-phase extraction (SPE) was used in conjunction with the Artemia bioassay. For T-2 toxin, HT-2 toxin, and 4,15-diacetoxyscirpenol, LC50/SPE values after solid-phase extraction were 21, 83, and 130 micrograms/L. The use of river and stream waters and chlorinated water did not seem to interfere with the bioassay.

Animals