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E Thaisz

Publications and source records attributed to E Thaisz.

7 recordsLinked to original sources
PubMed1991

[Experience with functional insulin therapy: metabolic follow up and patient cooperation].

Functional insulin substitution, an insulin regimen made up of two daily injections of intermedier acting insulin and prandial boluses of regular insulin, was to be introduced in 49 type 1 diabetic patients, as previous regimens consisting of two or three daily injections proved to be inefficient due to the patients' lifestyle or inherent metabolic lability. 45 patients were treated with human insulin injected by NovoPen. In 38 cases therapy was changed in the frame of a one-week, small-group, inpatient, structured educational course. After a mean 14 months of follow-up metabolic status improved in 33 cases while there was further derangement in 16. 18 patients were practicing true functional therapy ie. doing blood glucose tests before each injection. Another 22 diabetics were trying to achieve better metabolic control through 2-3 daily blood glucose tests and insulin dose corrections. Metabolic status was not affected by the frequency of blood glucose testing, rather by the raising of the daily dose of Actrapid insulin in conjunction with the switch in therapy acting beneficially. All patients insisted on using NovoPen further on.

Adult↗
PubMed1984

Non-specific cellular immunity in type I and type II diabetes.

Antibody-dependent cellular cytotoxicity (ADCC) against human erythrocytes was investigated in 39 type I and 63 type II diabetic patients in comparison to 177 healthy blood donors. The cytotoxic capacity of lymphocytes from diabetics was significantly increased. The highest values were measured in insulin-treated type II diabetics (after secondary failure of a previous sulfonylurea therapy).--It is suggested that in certain cases of type II diabetes an increased unspecific K cell-and/or antibody-dependent cellular cytotoxicity plays a pathogenetic role in the development of the disease. The latter might possibly be directed against insulin receptors.

Antibody-Dependent Cell Cytotoxicity↗
PubMedDate not supplied

Experiences with functional insulin substitution: a follow-up study on control and patient compliance.

Functional insulin substitution, an insulin regimen made up of two daily injections of intermediate-acting insulin and prandial boluses of regular insulin, was to be introduced in 49 type 1 diabetic patients, as previous regimens consisting of two or three daily injections proved to be inefficient due to the patients lifestyle or inherent metabolic lability. Forty-five patients were treated with human insulin injected by NovoPen. In 38 cases therapy was changed in the frame of a one-week, small-group, inpatient, structured educational course. After a mean 14 months of follow-up metabolic status improved in 33 cases while there was further derangement in 16. Eighteen patients were practising true functional therapy, i.e. doing blood glucose tests before each injection. Further 22 diabetics were trying to achieve better metabolic control through 2-3 daily blood glucose tests and insulin dose corrections. The metabolic status was not affected by the frequency of blood glucose testing, rather by raising of the daily dose of short acting insulin in conjunction with the switch in therapy acting beneficially. All patients insisted on using NovoPen further on.

Adult↗