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Biomedical subjects

E Thiele

Publications and source records attributed to E Thiele.

At least 19 recordsLinked to original sources

[Chronic aspecific respiratory tract diseases in workers of pig-breeding farms].

To study chronic nonspecific respiratory diseases of people working in industrial swine confinement buildings, a cross sectional study was initiated. Based on history of diseases, clinical and parameters of ventilatory screening in 238 swine producers a frequency of chronic respiratory symptoms were found in 25.6%. The possible dependence on age, sex, smoking history, working conditions and duration of activity was investigated. The influence of professional and non professional factors had different intensity. The results of investigations of working conditions did not exceed the permitted maximal working place concentrations. So they could not prove the large frequency of respiratory diseases.

Age Factors

Prospective study of the incidence of ultrasound-detected hepatic hematomas 2 and 24 hours after percutaneous liver biopsy.

Recently, a high incidence of hepatic hematomas following percutaneous liver biopsy was reported. This induced us to undertake this prospective ultrasound examination before, as well as 2 and 24 h after, percutaneous liver biopsy, using a Menghini needle (O 1.4 mm), in 93 patients for diagnostic purposes. Two hours after biopsy a small subcapsular fluid margin was found in one patient (1.1%) which disappeared within 24 h. We conclude that hepatic hematomas are not frequent following percutaneous liver biopsy and that it remains a safe diagnostic procedure to find out the reason for chronically elevated liver enzymes and evaluate suspected diffuse parenchymal lesions of the liver.

Adolescent

[Permissible dermal exposure dose and safety level for herbicide residues as an occupational hygiene standard for the evaluation of exposure].

At preparing mixtures for spraying, application of pesticides and entering treated areas workers are subject of potential exposure, more than 90% via skin. The limitation of dermal exposure requires hygiene-toxicological threshold limit values. On the basis of toxicity data from experiments with animals a permissible dermal exposure dose for pesticide residues is determined. For that a safety and a resorption factor are used, which are fixed in dependence on the toxic effects. The permissible dermal exposure dose is the basis of the calculation of a safety value for residues on plant surfaces and reentry time.

Environmental Exposure

[Results of occupational medicine pesticide research].

The conditions of the pesticide exposition in agriculture are described, including results of analyses of acute consequences of expositions to selected agents as well as in workers exposed to pesticide application for several years.

Agricultural Workers' Diseases

[Respiratory function disorders caused by agrochemical exposure].

With the aim to evaluate possible influences of exposition to agrochemicals upon the respiratory system, the ventilatory parameters VC, FEV1,0, FIV1,0, and the values of PaO2 and PaCO2 were investigated in 93 males professionally exposed to mineral fertilizers, and in 69 males professionally exposed to pesticides--both groups working in agrochemical centres. A control group consisted of 162 males without exposition to agrochemicals. In exposed workers mean values of VC, FEV1,0, and PaO2 were lower (highly significant) compared with the control group. Mean values of FEV1,0, FIV1,0, and PaO2 in workers exposed to mineral fertilizers were in the borderline region. Influences upon the respiratory system should be further investigated with regard to long-term effects and to fitness for the job.

Adult

[Epidemiological study on the demonstration of precipitating antibodies against Micropolyspora faeni in agricultural workers].

The authors report on the frequency (as determined by the double diffusion test according to Ouchterlony) of circulating precipitating antibodies against thermophil actinomycetes of the genus Micropolyspora faeni in 1666 blood samples from 1376 agricultural workers. These workers belonged to the main professional categories in two districts of the German Democratic Republic and were examined by members of the Research Group on Occupational Medicine in Agriculture of the Ernst Moritz Arndt University during the years 1972-1975. 290 workers were examined twice or three times in a longitudinal study. Positive serological findings were obtained from 5.1% of the subjects under investigation. There were no statistically significant differences with regard to occupational category, sex, age, and season. Nevertheless, there were marked regional differences. The results obtained show that there is no need for special medical supervision of the agricultural workers with regard to thoracic actinomycosis (farmers' lung). Further examinations are of course necessary in case of suspected or clinically manifest affection.

Actinomycetales Infections

[Acute Hedolite poisoning in humans].

Severe intoxication was contracted by an agrochemist who had handled Dintro-O-kresol (DNOC) over several days. The symptoms are described in this paper. The half-life calculated from the blood level course amounte to 148 hours. The particular case of intoxication is evaluated, and reference is made to literature, before the reader's attention is drawn to certain major and crucial aspects that should be duly considered in any use of DNOC, such as limitation of exposure, blood level monitoring, and availability of adequate safety clothing.

Adult

[Electroneurographical examination of agricultural workers exposed to plant protective agents].

Clinical and neurological as well as electromyographic examinations were made on twenty-five subjects working in agriculture and handling plant protection products. Measurements of the rate of nerve conduction were made on the peroneal and median nerves. The average rate of conduction of the peroneal nerve was found to be reduced in persons who had been exposed o plant protectives for more than three years. Electroneurography appears to be useful method of recognizing polyneuropathic symptoms of chronic and toxic affections caused by insecticides.

Adult