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Biomedical subjects

E Thybo

Publications and source records attributed to E Thybo.

9 recordsLinked to original sources
PubMed1991

[Fetal hydronephrosis].

Antental intervention in cases where the foetus was suspected of having hydronephrosis has been the subject of intense discussion in recent years where the diagnosis was technically possible. The object of this investigation was to assess the end result in foetuses with hydronephrosis diagnosed prenatally and who were treated expectantly without intervention in utero. Fourteen consecutive cases of suspected foetal hydronephrosis are described. In four of the cases the hydronephrosis was transient without consequences for subsequent renal function. Three infants died, however, immediately after birth. All three were shown to have multiple malformations and/or chromosome anomalies. Unilateral dilatation of the upper urinary tract (seven cases) was by and large, associated with a good prognosis. Foetuses with bilateral dilatation of the upper urinary tract (seven cases) had poorer prognoses but this might also be related to other serious malformations. If this is compared with the disappointing result obtained by prenatal intervention in the form of foetal surgery or introduction of vesico-amniotic stents, very little evidence is found in favour of in utero intervention. In the great majority of cases, conservative prenatal regime is preferable.

Abnormalities, Multiple↗
PubMed1988

Functional results after ileocystoplasty.

The functional results after ileocystoplasty were studied in seven patients with interstitial cystitis, irradiated bladder and neurogenic bladder dysfunction. None of the patients had had symptomatic improvement by medical or surgical means. All patients were suffering from urinary frequency and five patients had severe urge incontinence or suprapubic pains. Postoperatively the patients were followed from 8 to 66 months and evaluated by urodynamic examinations and interviews. Urinary frequency was improved in all patients but one with interstitial cystitis who had persisting suprapubic pains. None had residual urine volume greater than 30 ml postoperatively. It is concluded that bladder augmentation by ileocystoplasty is an excellent method of treatment for patients with contracted bladder secondary to interstitial cystitis, irradiated bladder, and detrusor hyperreflexia and sphincter dyssynergia.

Adult↗
PubMed1979

Epodyl treatment of bladder tumours.

Multiple, non-invasive bladder papillomas were treated with intravesical instillation of Epodyl in 44 patients. Irritative cystitis occurred in 16 per cent of the series, and in these cases Epodyl treatment had to be stopped. Total or partial disappearance of the papillomas was seen after 16 months of treatment in 43% of the total series. This was the minimum success rate, since all the patients who left the study were counted as failures. When the treatment could be carried through, total or partial disappearance of papillomas occurred in 19 of 29 patients (66%). Epodyl has a place in the treatment of vesical papillomas when other methods have failed.

Administration, Topical↗
PubMed1977

Surface topography of the healthy and diseased transitional cell epithelium of the human urinary bladder.

51 biopsies from healthy and diseased epithelium from human urinary bladders were examined by scanning electron microscopy. The luminal surface of the cover cells was marked by microvilli and microplicae. The replacement of the cover cells takes place by simple desquamination. This exposes cover cells having numerous microvilli, and these later develop characteristic microplicae. The ability to form cover cells is lost by the transitional epithelium following tumour formation. No tumour-specific surface morphology was observed.

Carcinoma, Transitional Cell↗
PubMed1976

A controlled investigation of the value of anticoagulant therapy in cases of prostatectomy.

Prior to prostatectomy, 182 patients were classified into two groups of 90 and 92 patients. The classification was performed so as to make the groups mutually comparable with respect to factors considered significant in connection with the risk of thrombo-embolism. The group with 90 patients was anticoagulated with marcoumar. The other group served as a control. There was no significant difference in mortality or thrombosis incidence between the two groups. There was a significantly larger loss of blood in the anticoagulated group. Five of the patients in the anticoagulated group died, while in the control group, 3 patients died. Epsilon-aminocaproic acid was not used on a routine basis.

Aged↗