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Biomedical subjects

E Traey

Publications and source records attributed to E Traey.

5 recordsLinked to original sources

Endocrine profiles in early pregnancies with delayed implantation.

Delayed implantation in cycles with ovarian stimulation and ovulation induction was observed in eight patients. Endocrinological evidence for ovulation during pregnancy is presented in three cases; in one of them the implantation was evidently rescued by a new active corpus luteum. All pregnancies had the following factors in common: (1) A delay in the detection of the first positive serum human chorionic gonadotrophin (HCG) by 4-5 days. (2) The corpus luteum was not rescued initially and menstruation started at low serum concentrations of 17 beta-oestradiol and progesterone between 12 to 18 days (13.8 +/- 1.9 days) after induction of ovulation. (3) Because of the negative HCG, menstrual bloodloss and low steroid hormone concentrations, a new ovarian stimulation was started and continued for some days until pregnancy was detected. On the basis of the endocrine findings, three different forms of delayed implantation could be distinguished. Two of the eight pregnancies had a normal progression until full-term delivery, two developed into echographically-confirmed clinical pregnancies, but aborted at 9 and 11 weeks after the first menstrual period had started. The remaining four ended with a preclinical abortion between 7 and 8 weeks.

Adult↗

Eisenmenger's syndrome and pregnancy.

The Eisenmenger's syndrome (E.S.) was redefined by Wood (1958) as pulmonary hypertension with reversed or bidirectional shunt at the aortopulmonary, ventricular or atrial level. This eponym is applicable to 12 different congenital cardiac lesions. Pregnancy in patients with E.S. is a particularly hazardous situation in respect to the prohibitive features of maternal and perinatal mortality (Gleicher et al., 1979; Jones & Howitt, 1965; Neilson et al., 1971).

Adult↗

Follicular rupture changes the endocrine profile of peritoneal fluid.

We determined the concentration of progesterone (P) and 17 beta-estradiol (E2) in peritoneal fluid 32 hours after endogenous luteinizing hormone surge (LH) or 34 hours after injection of human chorionic gonadotropin (hCG) in 4 groups of patients: group A: 5 natural cycles, unruptured follicles, mean concentrations of P (1.48 micrograms/l) and E2 (169 ng/l); group B: 28 stimulated cycles, unruptured follicles after an endogenous LH surge, mean concentrations of P (5.33 micrograms/l) and E2 (1 344 ng/l); group C: 13 stimulated cycles, ruptured follicles after endogenous LH surge, mean concentrations of P (446 micrograms/l) and E2 (59 500 ng/l); group D: 8 stimulated cycles, unruptured follicles after injection of hCG, mean concentrations of P (8.21 micrograms/l) and E2 (551 ng/l). The variations of the hormonal concentrations in peritoneal fluid are discussed.

Ascitic Fluid↗

Success of in vitro fertilization and embryo transfer in relation to the causes of infertility.

In 1984 163 patients were treated in our in vitro fertilization program, including 4 patients accepting embryos from the oocyte and embryo donation program. Twenty pregnancies were achieved with an average chance per transfer of 16,6%. The final success of IVF strongly depends on the cause of infertility. The best results were obtained for patients with tubal infertility, with a pregnancy rate of 15% per laparoscopy and 19% per transfer. There is a significant decrease in oocyte cleavage rate from tubal (61%) to male infertility (13%). Once the barrier of embryo formation is taken, there is no marked difference in the mean number of embryos transferred on the pregnancy rate after transfer, among the different patient groups. In patients with tubal infertility the pregnancy rate per cycle remains constant, resulting in a cumulative pregnancy rate of 40% after 3 cycles.

Antibodies↗

[Appendicitis in children].

In 218 children of less than 16 years old appendectomy was performed. Presence of appendicitis was confirmed histologically in 199 cases. The ratio boys to girls was two to one. In one third the appendix had perforated. Administration of a combined Ampicillin-Metronidazole antimicrobial therapy, started during surgery, proved to be very efficacious in avoiding infectious complications. In this group the complication rate remained below 3%.

Adolescent↗