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Biomedical subjects

E Tunçbay

Publications and source records attributed to E Tunçbay.

6 recordsLinked to original sources

Spinal hydatid disease.

Vertebral hydatid cysts are rare and found in less than 1% of all the cases of hydatidosis. Neural compression is common in vertebral hydatidosis. The prognosis is generally regarded as very poor. This paper examines the natural history and complications which may arise during the treatment of vertebral hydatid cyst, and discusses their treatment. Thirteen cases of hydatid disease affecting the vertebrae are presented. The patients were admitted with symptoms of spinal cord compression. Twelve were treated by laminectomy and one by costotransversectomy. Low back pain radiating to the legs and lower extremity weakness were the predominant symptoms. Different degrees of pareses were present in 12 patients. Nine patients had impaired sensation in lower extremities. In 13 patients, 27 operations were performed. The major complication of surgery was the death of one patient due to the formaline irrigation. The surgical goal should be an extensive removal of the cysts and affected bone. The surgical area needs to be irrigated with hypertonic saline. Mebendazole or albendazole therapy seems to retard the recurrences and control the disease.

Adolescent↗

Surgery of intramedullary spinal cord tumors.

The diagnosis and management of intramedullary spinal cord tumors have been significantly influenced by new diagnostic and surgical tools such as MRI, ultrasonic aspiration, intraoperative ultrasound, and evoked potential monitoring. In this study we compared the surgical results of our earlier cases using conventional methods with more recent cases using these new methods. We report our experience based on 44 adult cases. Histologic diagnosis revealed ependymoma (20 cases), astrocytoma (15 cases), glioblastoma multiforme (1 case), and other histologic diagnoses (8 cases). We performed 20 gross total resections, 19 partial resections, and 5 biopsies. The mean follow-up period was 25.8 months (3 months-10 years). Surgical results were improvement in 11 patients (25%), stabilization in 24 (54%), and deterioration in 9 (20%). The first 28 cases (group A) were diagnosed using conventional myelography and CT myelography. The more recent 16 cases (group B) were diagnosed with MRI and operated on using techniques such as ultrasonic aspiration, intraoperative monitoring and ultrasound imaging. Radical surgery (total excision) was performed in 36% (n = 10) of group A, while it was possible in 62% (n = 10) of group B. Deterioration after operation was noted in 28% (n = 8) of group A, but only 6.2% (n = 1) of group B. These results stress the importance of a preoperative MRI scan and the positive effects of intraoperative ultrasound imaging, ultrasonic aspiration, and evoked potential monitoring on surgical results. With the help of these tools, most intramedullary spinal cord tumors may be diagnosed and treated surgically with significantly decreased risk. Radical surgery was possible in as many as 62% of our more recent patients. Partial resection with radiotherapy should be confined to patients with high-grade astrocytomas.

Adult↗

A prospective study on acute spinal injuries.

This work examines demographic and clinical characteristics of 163 consecutive cases of acute spinal injuries in a small area of Western Turkey, since 1982. These include all spinal injuries with or without neurological symptoms. Combined conservative and surgical methods were used for treatment. Age, sex, etiology, site of injury, radiologic findings, neurological status, and outcome are compared with the other studies. The results have been found to be parallel to those of the other studies except for some regional differences like an excess of tractor accidents.

Adolescent↗

A comparative study of brain-stem auditory evoked potentials and blink reflexes in posterior fossa tumor patients.

Brain-stem auditory evoked potentials (BAEP's) and blink reflexes (BR's) were recorded from 40 patients with clinical and radiological evidence of posterior fossa tumors. They were examined in three groups according to the anatomical location of the lesion: Group A included 15 patients with midline tumors; Group B included 14 patients with cerebellar hemispheric tumors; and Group C included 11 patients with cerebellopontine angle (CPA) tumors. More of the 40 patients had BAEP abnormalities (32) than BR abnormalities (24). All of the 11 patients with CPA tumors had some kind of BAEP and BR abnormalities. The 14 patients with cerebellar tumors showed the next most frequent abnormalities: 12 related to the BAEP's and seven to the BR's. The 15 patients with midline tumors showed the least number of abnormalities: nine related to BAEP's and six to the BR's. In the analysis of BAEP wave latencies and interpeak latencies, a wave III latency delay occurred in all groups; latencies of waves IV and V were more significantly delayed in patients with CPA and cerebellar hemispheric tumors, and the interpeak latencies of waves III-V and I-V were markedly prolonged only in patients with CPA tumors (p less than 0.01). In all tumor groups, early response (R1) of BR's was significantly delayed in comparison to a healthy volunteer control group (p less than 0.01), but R1 was more pronounced in cases of CPA tumors when compared with the other tumor groups. Although significant delays in direct and consensual late reflex components (R2) of BR's were noted in comparison to the control group, this delay could not differentiate one tumor group from another. In can be concluded that, while these tests reflect the functions of different cranial nerves and brain-stem tracts, BAEP monitoring is more sensitive than BR testing for the detection of brain-stem involvement in posterior fossa tumors. Cerebellopontine angle tumors almost always cause severe abnormalities in both tests. Cerebellar hemispheric tumors and midline tumors cause fewer changes in both BAEP's and BR's.

Adolescent↗

Orbito-cranial teratoma. A case report.

A case of congenital orbito-cranial teratoma is presented. Histological examination of this extremely rare tumour revealed unusual tissue elements derived from all three germinal layers.

Brain Neoplasms↗