Visualization of herpes simplex virus type 1 attachment to target cells using Staphylococcus aureus as a morphologic tag.
Staphylococcus aureus was used as a morphologic tag to allow light microscopic localization of herpes simplex virus type 1 (HSV-1) binding and attachment to HEp-2 target cells. The virus was bound to S. aureus through an anti-HSV-1 linkage. The complex was stable and the attached virus still infectious.
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