Biomedical subjects
Publications and source records attributed to E V Andrienko.
The paper deals with historical information concerning the investigation of mycotoxins and mycotoxicoses at the Institute of Microbiology and Virology of the NAS of Ukraine, main results of the works fulfilled for the last 25 years and possible trends of further investigations.
The activities of key enzymes of main metabolic pathways: glycolysis, pentose phosphate pathway and tricarboxylic acid cycle, have been studied in dynamics of cultivation of toxin-producing fungus Stachybotrys chartarum 13959a. Aldolase activity increased while that of succinate dehydrogenase decreased during the fungal growth. The activity of glucose-6-phosphate dehydrogenase was high during the first days of cultivation and then it decreased. The maximum yield of acetaldehyde has been observed during the first stages of cultivation and it has not been connected with quantitative yield of pyruvate.