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Biomedical subjects

E V Andrushchenko

Publications and source records attributed to E V Andrushchenko.

At least 19 recordsLinked to original sources

[The characteristics of the pharmacotherapy for patients with ischemic heart disease and hypertension in relation to age].

On the basis of literary and own findings the authors discuss disputable problems of the pharmacotherapy of ischemic heart disease and hypertensive disease in the age aspect including patients over 60 years of age. Approaches are analyzed to individual choice of adequate pharmacotherapy, criteria of selection and dosages with special emphasis of adreno-beta-blockaders and calcium antagonists as well as criteria of evaluation of pharmacotherapy.

Adrenergic beta-Antagonists↗

[Beta-adrenoblockaders and calcium antagonists in the treatment of patients with ischemic heart disease combined with hypertension].

The authors studied 67 patients with ischemic heart disease associated with hypertensive disease and revealed that the use of beta-adrenoblockaders and calcium antagonists resulted in a reduction of the manifestations of the disease, increase of physical load tolerance, optimization of its hemodynamic and oxygen provision. In patients under 60 years of age of beta-adrenoblockaders resulted in an increase of the myocardial contractility. This was not observed in those over 60 years of age. It is concluded that in patients combining IHD with hypertensive disease under 60 it is more preferable to use beta-adrenoblockers, in those over 60--calcium antagonists.

Adrenergic beta-Antagonists↗

[The hypotensive action of anaprilin in hypertension].

A study of the central hemodynamics in the course of treatment with anaprilin of 137 hypertensive patients with different clinico-pathogenetic variants and types of blood circulation indicates that the hemodynamic basis of hypotensive effect of the drug in patients with the hyperdynamic type is a reduction of the cardiac output and normalization of the changed general peripheral vascular resistance (GPVR) while patients with the hypodynamic type showed a distinct GPVR reduction and an increase of the cardiac output values. A hypotensive effect of anaprilin was noted in 82.5%.

Adolescent↗