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Biomedical subjects

E V Ermakov

Publications and source records attributed to E V Ermakov.

At least 19 recordsLinked to original sources

[Effectiveness of endobronchial administration of granulocyte concentrate in patients with various forms of chronic bronchitis].

The paper concerns the efficacy of endobronchial introduction of fresh donor leukocytic mass which was studied in 56 patients with chronic obstructive bronchitis and compromised immunity in hypoactivity of alveolar macrophages. The above treatment promoted correction of the immunity shifts, activation of alveolar macrophages and eventually better prognosis in relevant patients.

Adult↗

[Factors of protracted and recurrent course of chronic erosions of the stomach].

A study was made of the disease pathogenesis in 58 patients with recurrent chronic erosions of the gastric mucosa. It has been established that an important role in the relapses of the pathological process is played by pathological microflora, disturbances in humoral immunity and local microcirculation, and long existence of the zone of fibrinoid necrosis.

Adult↗

[Pathogenesis of acute pneumonia].

The patients with acute pneumonias demonstrated interdependent changes in lipid peroxidation (LPO), antioxidant system (AOS), immune system (IS), and in the pituitary-adrenocortical system (PAS), related to the character of the disease course. The most pronounced changes were seen in the patients with acute pneumonias eventuating in pneumofibrosis. The high level of LPO was combined with AOS depletion, immunodeficiency formation, and with dysfunction of the PAS. Antibacterial treatment did not exert any appreciable effect on the characteristics under study. Thus, the level of LPO and AOS status are important components in the pathogenesis of acute pneumonias, determining the character of the disease course and outcome. It is advisable that research work aimed at the design of the principles of antioxidant therapy may be intensified.

Acute Disease↗

[Evaluation of the effectiveness of differentiated therapy in patients with chronic erosions of the gastric mucosa].

Potentialities of differentiated therapy of patients with recurrent chronic erosions using medicinal and nonmedicinal methods in 119 patients were studied. During differentiated therapy one should take into account the condition of pathological microflora and circulatory disturbances. At the first stage routine therapy with subsequent incorporation of biogastrone was employed. At the second stage in the absence of a therapeutic effect local administration of a granulocytic concentrate was performed, and in insufficient effectiveness, electrocoagulation of chronic erosions of the gastric mucosa was indicated. The use of differentiated therapy contributed to a favorable prognosis of disease in these patients.

Adult↗

[Hemodynamics in viral-bacterial pneumonia in middle-aged patients].

Clinico-instrumental investigations were performed in 52 patients with virus-bacterial pneumonia in different periods of disease and 10-12 mos after discharge from hospital. Considerable changes in the hemodynamics of the lesser and greater circulation and left ventricular myocardial contractility preserving for a long time, particularly in a grave form of disease, were revealed. In long-term periods hypertension in the pulmonary artery system persisted. It could result in the occurrence of occult heart failure.

Acute Disease↗