[Hemodynamics and gas exchange in patients with chronic alcoholism during a controlled exercise test].
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Biomedical subjects
Publications and source records attributed to E V Gembitskiĭ.
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The main pathogenetic mechanisms and morphological picture of chronic asthmatic bronchitis are similar to those of bronchial asthma. The only difference is the absence of regular fits of asphyxia. Diagnosis of this disease is based upon the detection of the broncho-obstructive syndrome and verification of its allergic origin. Therapy of chronic asthmatic bronchitis is based on the same principles as that of bronchial asthma.
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Using a method of circadian ECG monitoring, the authors detected a peculiar phenomenon of frequent arrhythmic action of sympathomimetic inhalants in patients with bronchial asthma, mainly during remission. Possible interpretation of the results obtained was as follows: reduction during remission of functional beta block including heart block determining "cardioprotective" action in sympathomimetic inhalations; depletion of reserves of myocardial sympathetic mediators at the height of exacerbation of bronchial asthma; peculiarities of absorption of sympathomimetic inhalants with relation to a stage of disease. The authors discussed the potentialities and limitations of the use of sympathomimetic inhalants during exacerbation and remission of bronchial asthma with relation to patients' age and concomitant coronary heart disease.
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The article concerns one of the present-day problems in the teaching of the allergic diseases of the lungs, namely allergic bronchopulmonary aspergillosis. Discusses the disease diagnosis and clinical course, diagnostic approaches, efficient drug therapy, and prognostic aspects. Based on an analysis of the authors' own data, the problem of the possibility of the systemic pathoimmune manifestations associated with skin, eye and kidney injuries that occur during allergic bronchopulmonary aspergillosis is discussed.
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A parallel study of the activity of serum cholinesterase and excretion of cyclic guanosine monophosphate made it possible to distinguish 3 types of disorders of cholinergic regulation in exacerbation of bronchial asthma: cholinergic compensation, subcompensation and decompensation. The nature of correlations of the degree of disturbance of cholinergic regulation, intensity of allergic reaction and its type was established. The role and place of the choline blocking agents in multiple modality therapy of bronchial asthma were defined.
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