PubMed Health⌕ Search

Biomedical subjects

E V Kul'chavenia

Publications and source records attributed to E V Kul'chavenia.

At least 19 recordsLinked to original sources
PubMed2006

[A diagnosis for active urinary tract tuberculosis].

The paper details the procedure of a modified tuberculin challenge test, by keeping in mind the new parameters--the microcirculation of the urinary tract mucosa, which is recorded by Doppler laser flowmetry. The efficiency of the procedure was evaluated in 55 patients, including 25 patients diagnosed as having urinary tract tuberculosis and 30 with nonspecific infections. The urethral microcirculatory parameters studied during the tuberculin challenge confirmed the changes available in all the patients with urinary tract tuberculosis while they were absent in patients with nonspecific pathology. The proposed procedure may objectively record a diagnostic parameter. which improves the quality of diagnosis.

Adult↗
PubMed2003

[Extrapulmonary tuberculosis in West Siberia].

Nine hundred and seventy-three cases of extrapulmonary tuberculosis were analyzed by using the statistical reports from 14 West Siberian areas supervised by the Novosibirsk Research Institute of Tuberculosis, Ministry of Health of the Russian Federation. In 1999, extrapulmonary tuberculosis mortality again increased in Siberia, amounting to 4.4 cases per 100,000. Its incidence was 29.95 per 100,000. In the mortality structure, urogenital tuberculosis held the lead, peripheral lymph nodal tuberculosis and osteoarticular tuberculosis occupied the second and third places, respectively. Cases of advanced and complicated tuberculosis continue to be encountered; one of them is given as an illustration.

Adult↗
PubMed2003

[Significance of hematuria in phthisiourology].

The case histories of 299 patients examined at the Urogenital Department, Novosibirsk Research Institute of Tuberculosis, were analyzed to define the etiology of urogenital diseases. The diagnosis of urogenital tuberculosis was established in 112 (37.4%) patients; that of chronic nonspecific pyclonephritis was in 90 (30.1%) patients; chronic nonspecific prostatitis was detected in 49 (16.4%) males; urolithiasis was found in 20 (6.7%) patients. Twelve (4%) and 60 (20.1%) patients were diagnosed as having urinary system cancer and hematuria, respectively. Hematuria most frequently (75%) was indicative of the presence of a tumor. However, in renal tuberculosis, this sign was also revealed in 24.1% of the patients. It should be noted that there is a recent tendency for an increase in the incidence of diseases concurrent with hematuria: the kidney has been found to be concomitantly afflicted with tuberculosis and cancer in 2 patients; tuberculosis is concurrent with nephrolithiasis in 2 other patients.

Female↗
PubMed2002

[Toxic effect of antituberculous drugs on spermatogenesis].

To determine the impact of multidrug therapy on male sexual function, isoniazid was tested for their effects on spermatogenesis and the liver in an experiment on laboratory animals, then on spermatogenesis and spermatozoidal function by using the clinical data. There is evidence for that isoniazid given to mice produces no toxic effect on spermatogenesis. The drug in a dose of 0.5% fails to affect the mobility of spermatozoa in vitro. Combined antituberculous therapy does not cause any significant changes in the basic indices of a spermatogram in patients with different forms of tuberculosis. Intermittent combined antituberculous therapy does not result in the derangement of major constituents of a copulative act.

Adolescent↗
PubMed2001

[Ex juvantibus therapy in the differential diagnosis of urogenital tuberculosis].

To make a differential diagnosis, 274 patients were followed up. Of them 68 patients were further found to have urinary tuberculosis that was verified by hypodermic tuberculin test, 15 patients underwent tuberculin diagnosis without special preparation, and 20 required type 1 ex juvantibus therapy. Challenge treatment with low-spectrum antituberculous agents in usual doses for 2 months confirmed the diagnosis in 3 patients and excluded it in other 3.

Antitubercular Agents↗
PubMed1998

[Complications of polychemotherapy for renal tuberculosis].

The paper analyzes the incidence of adverse reactions caused by tuberculostatics used in the treatment of renal tuberculosis by follow-ups of 117 patients. Current polychemotherapy for renal tuberculosis has been found to be complicated by drug intolerance in 40.1% of cases. Intermittent intravenous injection of tuberculostatics causes side effects in 36.8% of patients while conventional treatment does in 59.1%. Pyrazinamide, streptomycin, and ethambutol are most toxic to patients with renal tuberculosis. There is a higher likelihood of drug intolerance in females with bilateral nephrotuberculosis complicated by chronic renal failure.

Adult↗
PubMed1998

[Analysing effectiveness of traditional treatment for urogenital tuberculosis by outpatients follow-up].

The paper presents the social and clinical structure of patients with urogenital tuberculosis through studies of 518 outpatient case histories. It has been ascertained that there is a prevalence of common and complicated forms of nephrotuberculosis, 82.4% of patients undergo surgery. Taking into account the fact that a fifth of patients cannot have long-term inpatient treatment, the incidence of Mycobacteriuria (67.9%), the prevalence of the disease, requiring organ-saving operations, the high degree of patients' disability, methods for intensifying urinary tuberculosis should be developed.

Aged↗
PubMed1995

[Possibilities of the use of immobilized proteolytic enzyme immozymase in tuberculosis].

The paper summarises the experience gained in the use of immozymase in tuberculous patients to advance the disease diagnosis and treatment. Immozymase proved valuable in obtaining sputum enriched with M. tuberculosis in patients who were previously considered noncarriers. M. tuberculosis became detectable in 28.3% of them. Immozymase instillations of the urethra before its massage for stimulation of prostatic secretion led to getting secretion in all the patients (0.35 ml, on the average). Immuzymase inhalations were used in the treatment of purulent bronchitis in patients with destructive pulmonary tuberculosis in conservative and preoperative regimens. Postoperative immozymase inhalations promoted prevention of pleuropulmonary complications. Open treatment of the caverns with immozymase after cavernotomy shortens the treatment duration. Positive results were also reached in the treatment of pleural empyema.

Administration, Inhalation↗
PubMed1995

[Laser therapy in renal tuberculosis: mechanism of action].

Etiotropic therapy in urinary tuberculosis fails to provide adequate repair. Normalization of renal function requires additional pathogenetic measures, laser treatment, in particular. Experience with laser treatment is now available for respiratory tuberculosis only. Mechanism of action of low-intensity laser radiation in nephrotuberculosis and rationale for its use are described.

Antitubercular Agents↗
PubMed1992

[Extrapulmonary tuberculosis in children].

Extrapulmonary tuberculosis morbidity in children of the Novosibirsk region for the period of 10 years was analysed on the basis of the materials presented by the regional antituberculosis center. It was found that 44 children has extrapulmonary tuberculosis which accounted for 17.9% of the total number of sick children and 5.7% of all extrapulmonary tuberculosis patients. Tuberculous lymphadenitis was diagnosed in 50% and bone-and-joint tuberculosis in 27.3% of cases; nephrotuberculosis occupied the third and ocular tuberculosis the fourth place; 20% of sick children were detected after their examination and 80% after surgery for other general diseases. Complications of the main process at the moment of application for help had 18.2% of children. The basic causes of later extrapulmonary tuberculosis diagnosis in children is the absence of awareness for tuberculosis in the general practitioners and inadequate work carried out in tuberculosis infection foci.

Adolescent↗
PubMed1992

[State of nonpulmonary tuberculosis care in West Siberia].

Basic epidemiologic parameters in relation to extrapulmonary tuberculosis were analysed in 6 regions of West Siberia as well as the state of the material-technical base of extrapulmonary service in these areas. Despite a general reduction of the revealed incidence and morbidity of extrapulmonary tuberculosis, the true incidence persists at a high level with predominance of advanced forms of the process. One of the causes of this situation is insufficient material-technical support of extrapulmonary tuberculosis service in West Siberia.

Humans↗