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Biomedical subjects

E V Kuleshov

Publications and source records attributed to E V Kuleshov.

At least 19 recordsLinked to original sources

[Principles of the treatment of surgical diseases in elderly and aged patients with diabetes mellitus].

Based on his experience of treatment of more than 5000 diabetic patients with surgical diseases, the author describes basic principles of management of these patients before, during and after operation. Combined treatment is based on compensation of diabetes, fluid-and-electrolyte balance and acid-base equilibrium. Blood glucose before operation must be limited to 8.3-8.7 mmol/l, ketoacidosis must be absent. During 3-4 days after operation doses of insulin must increase from 0.4-0.5 to 0.8-0.9 U/kg. Energy value of the diet must be not less than 9375-10,450 kJ bearing in mind glucose administered intravenously. Choice of the anesthetic method which has the least negative influence on carbohydrate metabolism and hemostasis as a whole is analyzed. Diabetic patients with surgical diseases can be operated with favourable outcome only in compensated diabetes and balanced homeostasis.

Acid-Base Equilibrium↗

[Preoperative determination of the boundaries of soft tissue necrosis in patients with diabetes mellitus].

The authors examined 34 patients with diabetes mellitus and purulent diseases of the soft tissues and 40 persons who formed the control group. The study of local microcirculation in the purulent focus, in a purulent and closed wound by determining the oxygen tension in capillary blood (pO2) established by using an noninvasive method that a real possibility for determining the exact boundaries of tissue necrosis has appeared. This makes it possible to excise optimally the necrotic tissues and choose the techniques of applying primary, primary-delayed or early secondary sutures. In addition, the study of the dynamics of pO2 changes allows the course of the wound process to be followed up and, consequently, possible suppuration of the wound to be predicted.

Adult↗

[Study of regional blood flow in the prognosis of the process of healing of postoperative wounds].

The authors suggest using the regional blood flow in control over the course of the wound process after various types of laparotomy so as to prognosticate the possibility of suppuration of the postoperative wounds. Examination of 20 patients showed that the regional blood flow values depended on the operative trauma and the character of the inflammatory process in the abdominal cavity. Decrease of the regional blood flow in the wound to 24 ml/min/100 g and lower indicates that purulent inflammation will most probably develop in the postoperative wound.

Abdominal Muscles↗

[Early diagnosis of postoperative intestinal obstruction].

Forty-three patients were reoperated in the early postoperative period. In 27 of them the cause of early relaparotomy was postoperative intestinal obstruction. In 20 of these 27 patients the cause of postoperative obstruction were adhesive lesions. Of the 43 reoperated patients 31 showed distinct clinical signs and symptoms of postoperative obstruction. In 12 patients early diagnostic laparoscopy was performed due to unclear symptomatology. This allowed to obtain detailed information and to reduce the period of dynamic observation, to lessen postoperative risk, to avoid unnecessary relaparotomy.

Adult↗

[Treatment of non-clostridial anaerobic infections in patients with diabetes mellitus in an isolated controlled abacterial medium].

The work presents data on treatment of 28 patients with neclostridial anaerobic infection developed against the background of diabetes mellitus. It was shown that characteristics clinical symptoms of the ailment and express-microscopic examination of the native material from the wound facilitated making the correct diagnosis in most cases without using complicated microbiological and chromatographic investigations.

Adult↗