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Biomedical subjects

E V Loviagin

Publications and source records attributed to E V Loviagin.

At least 19 recordsLinked to original sources
PubMed2003

[Results of radiotherapy in patients with stage-II Hodgkin's lymphoma with mediastinal lymph node involvement].

Depending on size of intrathoracic lymph nodes, 65 patients with Hodgkin's disease (stage II) were divided into two groups using the mediastinal-thoracic index (MTI): MTI = 0.22-0.3 prior to irradiation and MTI (0.3. Mediastinal nodes showed complete regression immediately after therapy (34-49 Gy aimed at mediastinum) in 12.3% only. In 44 patients (67.6%), complete response was not observed until 3-6 months after treatment, sometimes 24 months. Tumor recurred outside area of exposure 2-4 years in 4 (10.8%) in group I and 2 (7%) in group II (p(3.841). No correlation between recurrence rates and intrathoracic lymph node size was established. 10-year survival in both groups was 89.1 and 92.8%, respectively.

Adult↗
PubMed2002

[Computerized and magnetic resonance tomography in the staging of lung cancer].

CT (157) and MRI (74) potential in lung cancer staging was studied. Central form was identified in 195 patients (75%). The data were compared in 34. Comparison with surgical evidence was carried out in 47 (CT) and 35 (MRI). Both procedures proved valuable. Use of CT cut down the gap between the results of clinical and surgical evaluation to 17%. Higher precision was achieved by MRI application which was demonstrated by a comparison of the sensitivities of both procedures attained in evaluating the three parameters. The sensitivities of MRI (96%) and CT (90%) in the detection of intrathoracic lymphadenopathy were almost identical. MRI was superior to CT in detecting large vessel involvements (sensitivities--91 and 42%, respectively) as well as those of the pleura, pericardium and thoracic wall.

Humans↗
PubMed1992

[Ultrasonic tomography of the mediastinum in the staging of lung cancer].

Results of standard X-ray tomography, computed tomography and ultrasonic tomography (UT) used for detecting mediastinal metastases from lung cancer were compared in 50 patients who were later operated on. UT sensitivity in the diagnosis of paravasal lymph node involvement proved superior to that of X-ray tomography and only slightly yielded to that of computed tomography. As regards bifurcation lymph node assessment, results of the radiation imaging techniques were similar to those obtained by surgery. Ultrasonographic signs of tumor spreading to the mediastinum were observed in cases of stage IIIa-IIIb tumors only. UT assured detection of metastases in normal-sized lymph nodes of the upper mediastinum. Combined application of standard X-ray and ultrasonic tomography of the mediastinum assured better staging of tumor roughly in half the patients. Absence of X-ray signs of mediastinal lymph node enlargement is considered a direct indication for UT.

Adenocarcinoma↗
PubMed1991

[Radiographic and endoscopic studies in the diagnosis of persistent growth and recurrence of central cancer of the lung after radiotherapy].

Roentgenologic and bronchoscopic examination was performed in 75 patients with central carcinoma of the lung 3-5 months following radiation treatment and every 3-4 months thereafter up to 36 months and longer to establish optimal schedule of those procedures to evaluate response and timely diagnosis recurrence or progression of disease. Complex application of X-ray and endoscopy in lung cancer patients every 3-4 months following radiotherapy assures timely diagnosis of relapse or progression.

Adult↗
PubMed1991

[Possibilities of contact chromatic thermography in the diagnosis of lung cancer].

Thermographic results were analyzed in 40 lung cancer patients and in 2 patients with acute pneumonia. The diagnosis and spreading of disease were established during x-ray, bronchological and morphological investigations. Normal temperature distribution was observed on the skin surface of lung cancer patients. The appearance of local hyperthermia did not depend on a stage of lung cancer. The sensitivity of chromo-thermography in establishing lung changes in tumors was 80% but thermosemiotics was not specific for cancer only. Similar thermosemiotics was noted in acute pneumonia. Comparative assessment of temperature distribution on the chest surface and perfusion scintigraphy in 24 patients made it possible to give correct interpretation of various temperature drop values in hyperthermia.

Adult↗
PubMed1989

[Organization of fluorographic examinations of the population in large cities].

A 5-year experience with fluorographic examination of the population of Leningrad is described. The data show that it is untimely to prolong the intervals between check fluorographic examinations. Difficulties in forming the risk groups are also indicated. Ways for improving organization of fluorographic examinations by using the available reserves are defined. On the whole, the present arrangement of prophylactic fluorographic examinations is rather efficient in regard to early detection of many pulmonary diseases including tuberculosis and peripheral cancer of the lungs.

Humans↗
PubMed1987

[Bronchoscopy in the outpatient examination of patients].

Diagnosis was improved and the duration of examination and costs reduced as a result of bronchoscopy carried out in outpatients. Lung cancer was frequent in males over 45 years with a long history of heavy smoking. In such cases, the disease presented as long-lasting acute pneumonia. The high diagnostic value of the procedure and freedom from complications suggest that it be more closely integrated with outpatient treatment practice.

Adult↗
PubMed1987

[The choice of surgical intervention in mitral defects].

Under analysis were clinical data and roentgencardiometric parameters in 181 patients with mitral diseases. The most informative roentgencardiometric parameters were established and a quantitative diagnostic algorithm was created with the help of a mathematical method for the choice of the operative procedure. The correct choice was made in 79% of the cases. The diagnostic algorithm developed is thought to be most expedient for use in patients with combined mitral defects. The procedure of quantitation of cardiometric parameters and summing their diagnostic coefficients is simple and not time-taking.

Algorithms↗
PubMed1987

[Scintigraphic and x-ray bronchologic evaluation of the spread of bronchogenic cancer].

The potentialities of perfusion and positive pulmonary scintigraphy for the determination of spreading of bronchogenic cancer were studied in 83 patients and in terms of the assessment of effectiveness of radiation therapy in 28 patients. The results obtained by means of radionuclide methods were compared with those of roentgenography, tomography and bronchofibroscopy. Disorder of perfusion in the lung was shown to depend on primary tumor spreading as well as on the involvement of some groups of lymph nodes. Changes in the blood flow were greater than a degree of primary tumor spreading. It was shown that perfusion pulmonary scintigraphy could be used to predict a volume of radiation therapy. Scintigraphy of the chest with 67Ga-citrate permitted the determination of tumor sizes which was important for central cancer. At the same time potentialities for the detection of lymph node involvement were limited resulting from difficulties in differentiation of the affected lymph nodes from a primary tumor.

Adenocarcinoma↗
PubMed1984

[Possibility of noninvasive determination of left ventricular volume from a single minor axis].

The authors analyzed the left cinoventriculography data in 425 patients with various heart diseases in whom the volumes of the left ventricle varied from the normal to considerably increased values. It was established that the ratio of the transverse axis to the longitudinal one varied from 0.25 to 0.85 which suggests that it is not advisable to calculate the volume of the left ventricular chamber according to the formula of the volume of the ellipsoid of revolution whose long axis is replaced by the double value of the minor axis. Actually, the acceptable accuracy of the calculation of the volume by this formula may be obtained only when the transverse axis equals 4-4.5 cm. The studies have shown that the formula suggested by L. Teichholz is most optimal. The results obtained with the formula showed a good correlation with the volumes determined with the help of the cinoventriculogram (r = 0.93 +/- 0.04). This formula (Formula: see text) should be used for calculating the volumes of the left ventricle during echocardiography.

Adolescent↗
PubMed1983

[Characteristics of the phase of blood expulsion from the left ventricle in arterial hypertension and aortic valve stenosis].

A study of 96 patients (23 controls, 57 patients with arterial hypertension and 16 with aortal stenosis) has shown the ascending aortal pressure curve to conform to the ascending exponent with different time constants in all cases. The expulsion time constant for middle age (44 +/- 4 years) was 0.063 +/- 0.002 s, with the expulsion time/time constant ratio of 4.01, in normal controls; 0.095 +/- 0.03 s and 2.6, respectively, in hypertensive patients; and 0.170 s and 1.72, respectively, in patients with aortal stenosis. The difference between ventriculographic and estimated left ventricular stroke volumes was not significant (p less than 0.001). Hemodynamic resistance to expulsion was 132 +/- 6 din X s X cm-5 in the controls, and 299 +/- 14 and 305 +/- 28 din X s X cm-5, respectively, in patients with arterial hypertension and aortal stenosis.

Adult↗
PubMed1982

[Effect of mitral and aortal regurgitation on the function of the left heart ventricle].

The paper is based on the data obtained through quantitative analysis of left cinoventriculograms and heart chamber catheterization in 136 patients with mitral and aortal regurgitation of the 2nd--4th degree. Left ventricular productivity was assessed on the basis of total stroke performance and capacity. Left ventricular productivity was found to be always increased in both kinds of regurgitation, irrespective of myocardial condition, and to increase further along with the increase in regurgitation volume. These hemodynamic parameters cannot be used for the assessment of myocardial contractility. In acquired valvular defects, myocardial contractility disorders may be diagnosed using the expulsion fraction, mean rate of muscular fibre shortening, relative mean expulsion rate and muscular contractility index as diagnostic parameters. The clinical value of contractility assessment is in that it can distinguish developing left ventricular failure from clinically similar symptom complexes and enables a more objective choice of treatment. Decreased myocardial contractility parameters in mitral and aortal regurgitation provide no counterindication for the correction of the defect.

Aortic Valve Insufficiency↗
PubMed1979

[Myocardial contractile capacity of the right ventricle in lesser circulation hypertension and in right ventricular insufficiency].

The informative value of some indices of myocardial contractility, calculated from curves of pressure in the right ventricle and pulmonary artery, was determined in 119 patients suffering from mitral heart disease with various grades of pulmonary hypertension in 25 patients who did not have a heart disease. The dependence of these indices on the grade of pulmonary hypertension and severity of the clinical symptoms of right-ventricular insufficiency was also studied. The Siegel-Sonnenblick contractility index proved to be the most informative index of myocardial contractile function. It was reduced in patients with right-ventricular insufficiency. With an increase in pulmonary hypertension, the average rate of increase in intraventricular pressure in the phase of isovolumic contraction grows sharply, which indicates to considerable hyperfunction of the right ventricle.

Blood Pressure↗