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Biomedical subjects

E V Lutsevich

Publications and source records attributed to E V Lutsevich.

At least 19 recordsLinked to original sources
PubMed2001

[Pancreas as one of the targets of "auto-enzyme explosion" in pancreatitis].

The authors consider pancreatitis not as a nosological unity but as a clinical manifestation of enzymatic or autoenzymatic aggression. Based on clinical, histopathomorphological examinations, the authors describe pancreatogenous enzymatic injury of organs and tissues (pancreas, heart, kidneys, liver, gastrointestinal tract, etc). For 4-8 days to 2-10 years the syndrome may damage not only pancreatic parenchyma, but also vascular structures with formation of general vasculitis, lymphangitis and subsequent thrombotic microangiopathy. The authors regard pancreas as one of the target organs--of general disease, in which serious injuries of other organs and tissues may prevail over changes in the primary zone of aggression.

Adult↗
PubMed1997

[Combined surgical interventions in gastroduodenal ulcers].

Diagnosis and treatment of gastroduodenal ulcers combined with abdominal pathology are discussed. The results of combined operations in 158 patients are analysed. Most often gastroduodenal ulcers were combined with hiatal hernia (62%), peritoneal adhesions (17.7%), cholecystitis (17.7%), abdominal wall hernia (10.1%). Good long-term results were achieved in 69.7% of the patients, satisfactory results-in 26.9%, unsatisfactory-in 3.4%. Combined operations are effective in treatment of peptic ulcers and concomitant disorders.

Adult↗
PubMed1993

[Surgical treatment of diseases of the small intestine].

The article deals with experience in surgical treatment of 375 patients with various diseases of the small intestine, rare diseases (tuberculosis, enterolithiasis, tumors, etc.) among others. These diseases were usually manifested clinically in the late stages by ileus, peritonitis or bleeding into the gastrointestinal tract. Most patients with surgical diseases of the small intestine were subjected to operation for emergency indications. Such instrumental methods as laparoscopy, selective endoscopic radiocontrast study of the small intestine, angiography, etc. are important in the diagnosis of the diseases. The authors emphasize the high diagnostic efficacy of a special method of selective endoscopic radiocontrast study, especially in tumors of the small intestine. According to the authors, general mortality rate in diseases of the small intestine is high (13%) and is mainly due to such diseases as disorders of mesenteric blood circulation, incarceration of the intestine in a hernia, adhesive obstruction, volvulus, etc. The authors claim that mortality in diseases of the small intestine can be reduced if early diagnosis, early hospitalization, and adequate surgical interventions are ensured. Among the factors contributing to increase of the efficacy of surgical operations the authors indicate efficacy of surgical operations the authors indicate precision techniques of intestinal suture application with atraumatic suture material, the use of complex biological protection of the anastomosis including treatment with low-frequency ultrasound and subsequent application of collagenic films in which antibacterial agents are deposited, and measures for stimulating reparative regeneration.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1991

[Diagnosis and treatment of gastrointestinal hemorrhage].

The article analyses the results of treatment of 4,430 patients with gastrointestinal bleeding in the last four decades. Two periods, from 1950 to 1969 and from 1970 to 1990, are compared from the standpoint of change of the disease structure, the methods of diagnosis and hemostasis. The number of hemorrhages of ulcer genesis reduced from 80 to 40.3%. Changes in the pattern of the disease is associated with improved diagnostic methods and recognition of pathological processes which were previously inaccessible to radiological examination, such as the Mallory-Weiss syndrome, acute ulcerations of the mucosa. The age composition remains relatively stable. Just like in the previous years, each third patient is over 6.0 years of age. Despite introduction of new methods of treatment, such as endoscopic arrest of bleeding, enteral feeding, a new method for management of penetrating ulcers and others, the mortality rate reduced only from 4.5% (1950-1969) to 3.4% (1970-1990). It is noted, however, that fatal outcomes in the last years prevail among patients aged 65-70 or older.

Age Factors↗
PubMed1991

[Ultrasonic diagnosis of benign diseases of the gallbladder].

The authors discuss experience in ultrasonic examination (USE) of the biliary tract in 1,068 patients with various benign diseases of the gallbladder; 536 of them were treated by surgery. It is shown that USE is a highly informative and authentic method in the diagnosis of benign diseases of the gallbladder. The article deals with the USE semeiotics of acute destructive cholecystitis, its complications, as well as chronic calculous cholecystitis and various benign acalculous diseases of the gallbladder. Among the existing methods of examination of the biliary tract, the authors claim USE to be most important and the main method in patients with benign diseases of the gallbladder of acalculous genesis.

Acute Disease↗
PubMed1991

[Rheovasography in the evaluation of conservative treatment methods in obliterating atherosclerosis].

The work discusses the results of treatment of 65 patients for arteriosclerosis obliterans of the lower limb vessels by means of various nonoperative methods. The clinical indices improved within the shortest period of time in the group of patients treated by a complex of measures including reinfusion of blood irradiated by ultraviolet rays. According to the findings of rheovasography, the rheographic index increased to a greater degree (+0.4) in patients who were treated by infusion of their own blood, which had been exposed to ultraviolet light, in combination with intravenous injection of drugs. Application of quantum hemotherapy alone was also effective, which was confirmed by increase of the rheographic index by 0.2. It is pointed out that the therapeutic effect of the method is mainly due to improvement of the blood rheologic properties and provision for the flow of blood along the main channel.

Aged↗
PubMed1989

[Local administration of contrical in the complex treatment of gastrointestinal ulcers].

The authors report the results of experiments and of multiple-modality treatment of gastroduodenal ulcers with the use of local inhibitors of proteolysis, with contrykal among other drugs. Experimental ulcers have been induced in rats according to Okabe. Eighty-three patients have been treated with the suggested schemes. The activities of lysosomal proteinases have been studied both experimentally and clinically. Local injections of contrykal into the ulcer had inhibited proteinase activity and had a positive therapeutic effect.

Adolescent↗
PubMed1989

[Acute acalculous cholecystitis in emergency surgery].

The authors discuss their experience in surgical treatment of 297 patients who were operated on for acute acalculous cholecystitis. Pointing out the multifactorial development of the disease, they attribute the principle role to the vascular and enzymatic genesis. From their own clinical experience, they recommend laparoscopic examination in the diagnosis of difficult and uncertain cases. The authors emphasize that active surgical tactics is necessary and that the approach to the management of patients with acute acalculous cholecystitis must be differentiated.

Acute Disease↗