PubMed HealthSearch

Biomedical subjects

E V Miller

Publications and source records attributed to E V Miller.

At least 19 recordsLinked to original sources

Should all in situ saphenous vein bypasses undergo permanent duplex surveillance?

OBJECTIVE: To evaluate the need for color duplex surveillance (CDS) for pure in situ bypasses beyond 6 months. DESIGN: We reviewed our in situ surveillance data from August 1987 to April 1994. Lower-extremity revascularization was performed using 245 pure in situ greater saphenous vein bypasses in 219 patients. The CDS of the entire bypass and inflow and outflow arteries was done prior to discharge, at 1 month, every 3 months in the first year, every 6 months in the second year, and annually thereafter. A peak systolic velocity of less than 45 cm/s throughout the bypass or a velocity ratio of greater than 3 (peak systolic velocity at the stenosis divided by peak systolic velocity at an adjacent normal bypass segment) were defined as abnormal during the review of this patient subset. The outcomes were analyzed. Patency and limb salvage rates were calculated by life-table analysis. PATIENTS: The mean age of this population (120 men and 99 women) was 67 years (range, 32 to 97 years). We analyzed all bypasses that were subjected to CDS for 6 months or more and identified 171 such bypasses. These bypasses were followed up for a mean duration of 30 months (range, 6 to 82 months). RESULTS: The primary and secondary patency and limb salvage rates at 5 years were 60.4%, 89%, and 92.1%, respectively (SE, < 10%). During the first 6 months of surveillance, 54 bypasses had abnormal CDS findings, and 117 had normal CDS findings. Arteriography was performed on 42 of these bypasses with abnormal CDS findings, and 37 had significant findings requiring direct surgical or endovascular intervention. Only two of 117 bypasses that had normal CDS findings for up to 6 months had to be revised later, compared with 43 of the 54 bypasses with abnormal CDS findings prior to 6 months, which were occluded or were revised (significantly different by chi 2 test [P < .001]). CONCLUSIONS: Vigorous CDS of pure in situ bypasses for up to 6 months is useful to detect bypass-threatening lesions. Continued CDS of a normal in situ bypass after 6 months may not be justifiable, as the incidence of lesions requiring later revision is minimal.

Adult

Skene's duct cyst.

Skene's duct cysts are rare. A review of the medical literature revealed Skene's duct cysts in 2 newborns and 1 adult in whom the cyst caused superficial external dyspareunia. A case of Skene's duct cyst is reported, which was associated with spraying of the urinary stream during voiding. Differential diagnosis includes urethral diverticulum, ectopic ureterocele, cystocele and Gartner's duct cyst.

Adult

Comparison of continuous-wave Doppler imaging, oculopneumoplethysmography, and the cerebrovascular Doppler examination.

Previous reports of continuous-wave Doppler imaging have combined that technique with periorbital Doppler studies. In the present report, 75 patients with findings suggestive of cerebrovascular insufficiency were evaluated using continuous-wave Doppler imaging, oculopneumoplethysmography (OPG-G) and the cerebrovascular Doppler examination (CDE). Each test was interpreted independently. Doppler imaging had an overall accuracy of 85%, with a 68% accuracy in identifying 50-70% stenoses and a 69% accuracy in identifying high-grade stenoses (greater than 70%) and occlusion. OPG-G had an overall accuracy of 85%, with a 55% sensitivity for 50-70% stenoses and an 89% sensitivity for high-grade stenoses and occlusion. The CDE had an overall accuracy of 84% and a 50% sensitivity for stenoses of 50-70% and an 88% sensitivity for high-grade stenoses and occlusion. As an independent technique, continuous-wave Doppler imaging achieves an overall accuracy comparable to that of OPG-G or the CDE. Its sensitivity to high-grade stenosis and occlusion, however, is less than that of the other techniques. Since CDE and OPG-G had a 94% sensitivity to carotid occlusion and a combined sensitivity to high-grade stenoses and occlusion of 88% and 89%, respectively, their combined use with Doppler imaging offers sensitivity to and differentiation of stenoses from occlusion.

Carotid Artery Diseases

Oculopneumoplethysmography, Doppler examination, and supraorbital photoplethysmography: a comparison of hemodynamic techniques in assessing cerebrovascular occlusive disease.

There noninvasive techniques used in the evaluation of carotid occlusive disease were compared in the same population group. The cerebrovascular Doppler examination (CDE) had an accuracy rate of 89%, oculopneumoplethysmography (OPG-Gee) an accuracy rate of 94%, and supraorbital photoplethysmography (SOPPG) an accuracy rate of 86%. With the combined use of the CDE and the OPG-Gee, the accuracy rate increased to 96% when the results were concordant, and the false-negative rate dropped to 3%. The data would suggest that the combined use of the CDE and the OPG-Gee offers an advantage over either technique used individually.

Arterial Occlusive Diseases

Performance evaluation: continuous lumbar epidural anesthesia skill test.

The evaluation of skills in anesthesiology residents is usually subjective and lacks demonstrable reliability. Therefore, an objective criterion-referenced skill test for measuring performance of continuous lumbar epidural anesthesia was developed. For such a test to be useful, it is necessary to demonstrate agreement among rater-observers. Eight performances of continuous lumbar epidural anesthesia were recorded on video tape and simultaneously rated by nine anesthesiology faculty observers to determine inter-rater reliability. Inter-rater agreement was analyzed by determining coefficient kappa for each item and the entire test. Coefficient kappa for the entire test was 0.82 indicating a high degree of agreement between raters on the performance or nonperformance of various items. Development and utility of skill tests are discussed.

Anesthesia, Epidural

Severe prostatic calcification after radiation therapy for cancer.

Severe symptomatic prostatic calcification was seen in 3 patients who had carcinoma of the prostate treated initially with transurethral resection, followed in 2 to 4 weeks by definitive radiation therapy. This complication is probably preventable if an interval of 6 weeks is allowed between transurethral resection of the prostate and radiation therapy.

Aged

Venous thromboembolism in the morbidly obese.

Obesity has been considered as a high risk factor in the development of thromboembolism. To test the validity of this hypothesis, the records of 564 morbidly obese patients who underwent gastric bypass for control of their obesity were reviewed. Four patients, 0.7 per cent, had proved fatal pulmonary emboli and three demonstrated detectable, but not fatal, embolization. Fifty-seven patients were studied prospectively with Doppler examinations of the lower extremities, and only one patient had a transient abnormality of venous thrombosis of the calf, which proved to be associated with a nonfatal pulmonary embolus. The morbidly obese patients are not at high risk from thromboembolism, and the prophylactic use of low dose heparin, which may increase known wound morbidity, is discouraged. Doppler ultrasound of the lower extremities, however, has proved usefulness to differentiate deep venous thrombosis of the lower extremity from other causes of pain in the leg of the morbidly obese.

Adolescent

Simultaneous adrenal and multiple bilateral renal cysts.

Benign cysts of the adrenal gland are rare. This is the first reported case of the simultaneous occurrence of an asymptomatic right adrenal cyst and bilateral multiple renal cysts. Excretory urograms with tomograms, renal aortography and ultrasound scanning were used to establish a non-invasive definitive diagnosis. There was no need for an operation since the lesions were benign.

Adrenal Gland Diseases

Doppler ultrasonic assessment of aortic stenosis by analysis of axillary arterial blood velocity upstroke time.

Rate-corrected velocity upstroke time (VUT) was calculated from analogue Doppler ultrasound recordings of axillary artery blood flow velocity in 25 patients with aortic stenosis documented by cardiac catheterization and in 14 normal individuals. The mean VUT in normal individuals was 0.11 +/- 0.02 second (+/- 1 SD), which was significantly lower than that of patients with aortic stenosis: 0.15 +/- 0.05 second (P less than 0.005). The VUT correlated with the aortic valve index and the aortic valve mean pressure gradient with correlation coefficients of 0.62 and 0.64, respectively (P less than 0.005). Arterial blood flow velocity assessment by Doppler ultrasound may be a useful noninvasive technique to evaluate patients with aortic valve disease.

Adult

Evaluation of cerebrovascular Doppler examination and oculopneumoplethysmography in a clinical perspective.

The cerebrovascular Doppler examination (CDE) and oculopneumoplethysmography (OPG-Gee) were compared in a single population group with no statistically significant difference found between the 2 studies. There appeared to be an advantage to combinant testing, for when the results of the 2 studies were concordant there was an accuracy of 94% and a false negative rate of 8%. Clinical correlation was available in 96% of the patients, providing adequate evidence to support the adjuvant role of non-invasive screening in the evaluation of symptomatic individuals. The percentage of false negative studies and the incidence of ulcerative disease make a diagnostic role impractical at present. For the asymptomatic individual, the diagnostic role of non-invasive screening seems justified. The false negative studies in the present series were confined to those vessels with 50-70% stenoses, which are difficult to assess angiographically and may be better characterized by hemodynamic evaluations.

Cerebral Angiography

Teaching effectiveness: evaluation of computer-assisted instruction for cardiopulmonary resuscitation.

Computer instruction for cardiopulmonary resuscitation (CPR), using a case-simulation program, was evaluated for its teaching effectiveness. First-month anesthesia residents, divided into two groups, A and B, underwent a cognitive evaluation on their 1st day of arrival and again on their 5th day. Both groups were provided with clear educational objectives and reading materials, a tutor was assigned to each student to answer specific questions. Students in group A, also given computer-assisted instruction (CAI), showed a significantly higher learning than those in group B, who served as controls. That CAI was a highly motivational form of learning was established by later voluntary participation in CAI of all group B students.

Anesthesiology