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Biomedical subjects

E V Minakov

Publications and source records attributed to E V Minakov.

10 recordsLinked to original sources

[Marked primary hyperparathyroidism not diagnosed before death].

A case of primary hyperparathyroidism (PHPT) in a patient 47 years of age diagnosed only at autopsy is reported. PHPT deposits of calcium into the muscles and heart vessels provoked irreversible cardiovascular disorders which caused death. Renal lesions were intravitally diagnosed as isolated urolithiasis but not as manifestations of PHPT. High blood levels of ionised calcium in this patient were thought a laboratory mistake though the above clinical symptoms should have excluded such opinion.

Adenoma↗

[Polymagnetolaser correction of vegetative and bioelectric imbalance in patients with duodenal ulcer].

90 patients with duodenal ulcer in exacerbation were divided into two groups. Control patients have received drugs against Helicobacter pylori (Hp). In addition to it, the test subjects were exposed to transcutaneous and reflex magnetolaser impact with consideration of baseline vegetative and bioelectric balance as shown by mathematical analysis of cardiac rhythm and Nakatani acupuncture diagnosis, monitoring of biopotentials of biologically active points. Impacts on general regulation systems in combined differential therapy of ulcer shorten ulcer healing, promote eradication of Hp, improve the condition of gastroduodenal mucosa.

Adult↗

[Methods of assessing the state of the digestive system in mass examinations of rural population].

On the basis of physician's logic a questionnaire has been elaborated for identifying the most common diseases of digestive system during mass medical check-ups of rural population. 98 combinations of signs were considered in the diagnostic algorithm for making conclusions regarding 11 diseases. The programme elaborated envisages recommendations on the volume of examinations necessary for verification of diagnoses. The questionnaire and rules governing it were verified for 152 patients. By means of mathematical statistics methods the informativeness of the signs used have been assessed. The analysis showed a great diagnostic value of choosing signs on the basis of physician's logic taking into account their pathogenetic correlation. The efficiency of questionnaires have been demonstrated and sufficient under conditions of automated examinations sensitivity (on the average for diseases 78.1%) and specificity (on the average for diseases 70.0%).

Algorithms↗

[Computer-assisted selection of therapeutic measures in ischemic heart disease and arterial hypertension during mass screening of a rural population].

Expert assessments of 537 case histories of patients with various coronary heart diseases made it possible to derive an algorithm for automatic choice of therapeutic and prophylactic measures. This approach was tested within the framework of the automatic system "Cardioscreening". It was shown that there was a good correlation between the automatic choice of therapeutic and prophylactic actions and the strategy of a skilled cardiologist.

Algorithms↗

[Results of automatic screening for ischemic heart disease and arterial hypertension among the rural population].

The results of automated screening for coronary disease and arterial hypertension within large-scale preventive checkups of rural populations are reported. A system was developed, on the basis of Rose's questionnaire and the Minnesota Code, for the assessment of resting ECG, using a remote-control advisory panel and new mini-computers of domestic manufacture. A total of 6133 residents from several districts were examined. The efficiency and quality of the operation of the automated screening system was assessed. The use of automated data collection and analysis in conditions of large-scale preventive checkups was shown to be an important contribution towards the objective of universal preventive medical examinations of the population, rural population in particular.

Angina Pectoris↗

[Use of an additionally intensified ECG in diagnosing ischemic heart disease].

The article deals with the use of the additionally intensified ECG while conducting the bicycle ergometric test in 92 patients with coronary heart disease. It has been shown that when additionally intensified ECG is combined with bicycle ergometry the use of such parameters as the value of ST segment depression and the average rate of ST integral increases the resolving capacity of the technique. In patients with a positive result of the test according to the criterion of ST segment depression (0.1 mV or more), the ischemic changes on the additionally intensified ECG are determined one grade earlier than the threshold exercise and precede the anginal attack. In patients with an anginal attack without diagnostically significant changes on the ECG during 1 mV = 10 mm intensification, the employment of additionally intensified ECG makes it possible to identify the ischemic changes and confirm the pain attack by objective findings.

Adult↗

[Possibilities of utilizing integral topography, vectorometry and spectral analysis of the complexograms for the diagnosis of ischemic heart disease].

Three approaches to the study of electric and mechanical heart activity were used, which were significant in the diagnosis of various variants of ischemic heart disease. The method of integral topography proved most applicable in the diagnosis of microfocal myocardial infarction. Infarctions which were marked by a typical clinical picture and the corresponding laboratory data (changes in enzymes, leukocytosis, etc)., but could not be sufficiently revealed in the commonly applied 12 leads of the ECG, were successfully identified due to changes in the ST--T zones of the topogram. In the diagnosis of ischemic heart disease attended with disorders of hemodynamics it is advisable to apply the histogram method of identification on the basis of spectral analysis of the complexograms, ballistocardiograms, arteriovenous pulsograms, and phonooscillograms. This method may also be used to assess the stage of circulatory insufficiency. In preventive examination for detecting ischemic heart disease, its painless variants in particular, it is advantageous to use the method of vectorometry of the ECG in in orthogonal leads with the subsequent solution of the diagnostic discrimination polynomials on a computer.

Ballistocardiography↗