[The effect of hypnotics on the acetylcholine content of the brain in reflex dystrophies of the stomach wall].
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Biomedical subjects
Publications and source records attributed to E V Moreva.
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The development of experimental neurogenic gastric ulcers was followed by a reduction in the noradrenaline and cAMP levels in the gastric tissue. The energy deficiency and upset nucleic metabolism were shown to underlie the structural lesions of the gastric mucosa. L-DOPA and etimizol stimulating the metabolic processes and the function of the sympathetic nervous system intensify the reparative processes during gastric ulceration.
It has been established in experiments that as visceral pathology arising during excess exposures advances, the deficiency of energy resources develops in the tissues of damaged organs. Application of the agents that normalize the function of the sympathetic nervous system (L-DOPA) and stimulate energy formation processes (ethimizol) accelerated reparative processes in damaged stomach and myocardium. Application of L-DOPA and ethimizol to the treatment of peptic ulcer patients produced a good therapeutic effect--an increase in the creatine phosphate content in the gastric mucosa and removal of the niche symptom in 80% of cases.
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